Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Paediatrica Indonesiana
Sri Rezeki Hadinegoro
Unknown Affiliation
Health Professions Medicine & Pharmacology

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Assessing the quality of life of asthmatic children using the PedQLâ„¢ Yulia Wigoeno; Rini Sekartini; Darmawan Budi Setyanto; Sri Rezeki Hadinegoro
Paediatrica Indonesiana Vol 51 No 5 (2011): September 2011
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (394.525 KB) | DOI: 10.14238/pi51.5.2011.245-51

Abstract

Background Asthma is the most common chronic respiratory illness in childhood. Its prevalence in Indonesia is 6.7 - 10%. Asthma influences growth, development and quality of life in affected children. Studies abroad have shown that children with asthma have a decreased quality of life (QoL), yet such data is limited in Indonesia.Objective To assess quality of life of asthmatic children in Indonesia, the influence of sociodemographic and medical characteristics on QoL, and to compare child self-reporting to their parents’ proxy-reporting.Methods This descriptive analysis, cross-sectional study was conducted from May to July 2010. We assessed the quality of life of asthmatic children aged 2-18 years using the PedsQLTM 4.0 generic scale.Results A total of 100 asthmatic children and their parents were included, with 43% of the subjects aged 8-12 years and a male to female ratio of 1.7:1. We observed that 26.8% of children who self-reported had impaired QoL, while 35% of children who reported by proxy had impaired QoL. In a multivariate analysis, we found the following characteristics to independently influence QoL: male gender (P 0.018 OR 0.26 95% CI 0.08 to 0.9) based on child self-report, and having partly controlled/uncontrolled asthma based on self-report and proxy-report (P 0.013 OR 6.24 95% CI 1.48 to 26.37 and P 0.018 OR 3.43 95% CI 1.24 to 10.05, respectively). There was good correlation between the self-report and the proxy-report on emotional and social functioning (r > 0.5), yet we found physical and school functioning to be weakly correlated (r < 0.5).Conclusions We observed a relatively high (26.8-35%) impaired QoL in asthmatic patients. Parental assessment of their child’s QoL was generally lower than the child’s self-assessment. Male gender is a protective factor against impaired QoL, but having partly controlled/uncontrolled asthma is a risk factor for lower QoL. [Paediatr Indones. 2011;51:245-51].
Adverse events following immunization (AEFI) reports of extended program immunization (EPI) in Indonesia during 1998-2002 Nastiti Kaswandani; Sri Rezeki Hadinegoro; Rulina Suradi
Paediatrica Indonesiana Vol 44 No 4 (2004): July 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (458.4 KB) | DOI: 10.14238/pi44.4.2004.153-9

Abstract

Background The incidence of adverse events following immuni-zation (AEFI) increased in correlation with the number of vaccinedoses. Meanwhile AEFI reports should be managed properly tomaintain the compliance and immunization coverage.Objectives The aims of this study were to investigate the inci-dence and profile of AEFI, its onset, severity, classification, andoutcome.Methods This study was a passive surveillance of AEFI reportsreceived by the National Committee on AEFI, Ministry of Health ofIndonesia, during 1998 to 2002.Results Two hundreds and four AEFI cases were reported; 4 casesas zero reports, 182 cases as individual reports, and 18 clusterreports. The AEFI incidence was 0.44 per 1 million doses of vac-cines. Vaccine reaction rate was 1 per 2.3 million vaccine doses.The most common vaccines reported as the causes of AEFI wereDTP, Polio, and TT. Among 182 reported cases, local or mild AEFIreactions were observed in 45, moderate in 49, and severe in 88.Based on WHO field classification, this study reported that 84 casesbelonged to coincidence, 72 to vaccine reactions, 13 to program-matic errors, 7 to injection reactions, and 6 to unclassified reac-tions. Forty-seven patients died, 12 had some sequelae, and 123completely recovered. Meanwhile, among the death cases, 70%occurred coincidently, 17% due to vaccine reactions, and 6 wereunclassified.Conclusions The incidence of AEFI in the extended program im-munization (EPI) in Indonesia during the period of 1998-2002 were182 cases, thus vaccine reaction rate was 1 per 2.3 million vac-cine doses. The most common vaccine which caused AEFI wasDTP. Most AEFI with severe symptoms happened in 4-24 hoursafter immunization.
The efficacy of suppository versus oral ibuprofen for reducing fever in children Suhesti Handayani; Sri Rezeki Hadinegoro; Sudigdo Sastroasmoro
Paediatrica Indonesiana Vol 45 No 5 (2005): September 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi45.5.2005.211-6

Abstract

Background Ibuprofen suppository is used to reduce fever inchildren who are unable to receive it orally. The effectiveness ofibuprofen suppository compared to that of oral ibuprofen has notbeen documented in Indonesian children.Objective The aim of this study was to compare the efficacy ofibuprofen suppository with that of oral ibuprofen for reducingfever in children.Methods This study was a randomized clinical trial without blind-ing on children aged 2-5 years with body weight of 12.5 to 16 kgwho had fever. Subjects received ibuprofen in either oral (7.5mg/kg) or suppository (125 mg) form. The temperature was mea-sured prior to ibuprofen administration, 30 minutes afterwards,and every subsequent half hour until the end of the sixth hour.Any observed adverse effects were recorded.Results Mean time needed for fever reduction was 2.72 (SD 1.1)hours in the suppository group, compared to 3.43 (SD 0.9) hoursin the oral group (P=0.004). The mean rate of fever reduction inthe suppository group was 0.90 (SD 0.4) °C/hour, while in theoral group it was 0.61 (SD 0.3) °C/hour. However, mean maxi-mum temperature lowering ability did not differ significantly [2.11(SD 0.7) °C for the suppository group and 1.99 (SD 0.7) °C, forthe oral group (P=0.489)]. There was no significant difference inmean duration of effect [220.8 (SD 83.0) hours for the supposi-tory group and 196.6 (SD 92.7) hours for the oral group (p=0.231)].Conclusions There was no significant difference between bothpreparations in maximum temperature lowering ability and dura-tion of effect. Temperature reduction was significantly fasterwith the administration of ibuprofen suppository
Randomized controlled trial of Phyllanthus niruri Linn extract Patria Vittarina Sarisetyaningtyas; Sri Rezeki Hadinegoro; Zakiudin Munasir
Paediatrica Indonesiana Vol 46 No 2 (2006): March 2006
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi46.2.2006.77-81

Abstract

Background Clinical benefits of antiviral treatment in childrenexperience varicella without complications, remains controversial.Phyllanthus niruri Linn extract as a natural medicine is used toincrease cellular and humoral immunity.Objective To determine the efficacy and safety of Phyllanthusniruri Linn extract in the treatment of varicella in children comparedto placebo.Methods This was a double-blind randomized controlled trial onchildren ages 2-14 years who experienced varicella without com-plications. Subjects were randomly assigned to receive eitherPhyllanthus niruri Linn extract syrup (5 mg/5ml, 3 times daily) orplacebo. Efficacy was measured by calculating the number of pap-ules and crusts after taking the extract for 4 days of administration.A five-day monitoring sheet to record daily follow up and adverseeffects of the subjects were given to their parents.Results Efficacy of Phyllanthus niruri Linn measurement basedon no more new papules occurred at the five-day monitor was de-tected in 46 subject (51.1%) of the Phyllantus niruri Linn groupcompared to the placebo group (P=0.723). Meanwhile, the differ-ence of efficacy based on time of crusts disappear in Phyllanthusniruri Linn and placebo group were 22 subjects (43.1%) and 15subject (30.0%), respectively (P=0.053). This finding proved haveclinical benefit (NNT=7.6).Conclusion There was no significant difference between the ef-ficacy of Phyllanthus niruri Linn and placebo in terms of the pre-vention appearing new papules and crusts. However, clinicallyPhyllanthus niruri Linn accelerates appearing and aborting crustcompared to placebo
Co-Authors Nastiti Kaswandani Patria Vittarina Sarisetyaningtyas Rini Sekartini Rulina Suradi Setyanto, Darmawan Budi Sudigdo Sastroasmoro Suhesti Handayani Yulia Wigoeno Zakiudin Munasir