Siska Mawaddatunnadila
Fakultas Kedokteran Universitas Muhammadiyah Surabaya

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Coronavirus Disease 2019 (COVID-19): Patogenesis, Manifestasi Klinis dan Pilihan Terapi Yelvi Levani; Aldo Dwi Prastya; Siska Mawaddatunnadila
Jurnal Kedokteran dan Kesehatan Vol 17, No 1 (2021): JURNAL KEDOKTERAN DAN KESEHATAN
Publisher : Faculty of Public Health, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/jkk.17.1.44-57

Abstract

Coronavirus Disease 2019 (COVID-19) ditemukan pada akhir tahun 2019 tepatnya bulan Desember di Kota Wuhan, Provinsi Huebei, China dan kemudian menyebar ke hampir seluruh dunia. Covid-19 disebabkan oleh betacoronavirus jenis baru yang cenderung mirip SARS-CoV dan MERS-CoV. Tujuan penulisan ini untuk memberikan telaah mengenai patofisiologi, manifestasi klinis, dan perkembangan penelitian tatalaksana Covid-19. Jenis review yang digunakan dalam artikel ini berbentuk literature review terhadap 41 artikel Covid-19 dengan menggunakan database PubMed dan Google Scholar. Covid-19 termasuk dalam genus betacoronavirus, hasil anasilis menunjukkan adanya kemiripan dengan SARS. Gejala umum di awal penyakit adalah demam, kelelahan atau myalgia, batuk kering. Serta beberapa organ yang terlibat seperti pernapasan, gastrointestinal, dan neurologis. Sampai saat ini, WHO dan beberapa Negara sedang melaksanakan uji klinis untuk menemukan obat yang tepat untuk Covid-19, studi ini bernama SOLIDARITY. Terdapat 4 kelompok dalam studi ini, yaitu kelompok LPV/r dan Interferon-beta, Remdesivir, Klorokuin dan Hidroksiklorokuin. Faktor virus dengan respon imun menentukan keparahan dari infeksi Covid-19. Gejala umum di awal penyakit adalah demam (83-98%), kelelahan atau myalgia, batuk kering (76-82%) dan sesak napas (31-55%). Dari telaah terhadap studi yang ada didapatkan bahwa sampai saat ini Remdesivir adalah obat yang paling berpotensi efektif terhadap Covid-19, walaupun begitu, masih dibutuhkan penelitian lebih lanjut dengan melakukan uji klinis yang lebih luas.
Hubungan Faktor Pelayanan Internal Kefarmasian Dengan Tingkat Kepuasan Orangtua Pasien Di Rumah Sakit Aisyiyah Siti Fatimah TJATUR PRIJAMBODO; MUSA GHUFRON; YELVI LEVANI; SISKA MAWADDATUNNADILA
HANG TUAH MEDICAL JOURNAL Vol 18 No 2 (2021): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

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Abstract

Abstract Background: Adequate health and well-being is a human right that has been recognized throughout the world. Indonesia has agreed to this as evidenced by the existence of Law No.36 of 2009. Hospital is one of the public health services that has pharmaceutical installation facilities, outpatient care, and so on. Objective: To determine the characteristics of pediatric specialist clinic patients and to determine the relationship between internal pharmaceutical service factors and the satisfaction level of pediatric specialist clinic patients at Aisyiyah Siti Fatimah Tulangan Hospital. Methods: This study is a descriptive analytic study with a cross sectional approach. The technique used is total sampling. The sample size was taken from all parents of pediatric specialist clinic patients who took medicine at the Pharmacy Installation at Aisyiyah Siti Fatimah Tulangan Hospital and met the inclusion criteria. The instrument used was satisfaction questionnaire that was collected from November to December 2019. The data obtained in this study were analyzed using the Chi Square method. Results: Based on the Chi Square test between Human Resources, Medicine, and Process, it shows p> 0.05, so there is no significant correlation between these variables and patient satisfaction. The results of the Chi Square test between the facilities and infrastructure variables showed p <0.05, which means that there is a significant correlation between the variable facilities and infrastructure for the pharmaceutical installation of Aisyiyah Siti Fatimah Tulangan Hospital and patient satisfaction. Conclusion: Internal service factor of pharmacy that has influence is infrastructure, while other factors in the form of human resources and processes have no relationship