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All Journal JURNAL ILMIAH KESEHATAN SANDI HUSADA Jurnal Ilmiah Kesehatan Sandi Husada
Ravinder Singh
Universitas Prima Indonesia
Health Professions Nursing Public Health

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Pengaruh Ekstrak Ikan Gabus (Channa striata) dan Metformin Terhadap Kontrol Glikemik Tikus Model Diabetes Melitus OK Yulizal; Ravinder Singh; Hendra Salim; Hendy Million
Jurnal Ilmiah Kesehatan Sandi Husada Vol 10 No 2 (2021): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v10i2.639

Abstract

Introduction; Diabetes mellitus (DM) is still a major problem where people with DM today range from 463 million adults aged 20-79 years (9.3%). Cork fish (Channa striata) is one of the natural ingredients containing albumin that is reviewed to have antioxidant activity in beta-pancreatic cells so it is believed to treat DM. Snakehead fish has some efficacy including; has antinociceptive activity, accelerates wound healing, and is an anti-inflammatory. Objective; To determine the effect of snakehead fish extract and metformin on glycemic control of male rats with diabetes mellitus. Methods; This study used an experimental method with a post-test-only control group design. Results; Based on the Kruskal Walis test, it showed (p < 0.05) meaning that there was an effect of EIG administration on reducing blood glucose levels in rats, and there was a reduction of HbA1c but not significant. Conclusion; The combination of snakehead fish extract 300mg/kg BW and metformin 45 mg/kg BW was superior in lowering blood glucose and HbA1c levels compared to single therapy with snakehead fish extract or metformin.
Pengaruh Ekstrak Ikan Gabus (Channa striata) dan Metformin Terhadap Kontrol Glikemik Tikus Model Diabetes Melitus OK Yulizal; Ravinder Singh; Hendra Salim; Hendy Million
Jurnal Ilmiah Kesehatan Sandi Husada Vol 10 No 2 (2021): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v10i2.639

Abstract

Introduction; Diabetes mellitus (DM) is still a major problem where people with DM today range from 463 million adults aged 20-79 years (9.3%). Cork fish (Channa striata) is one of the natural ingredients containing albumin that is reviewed to have antioxidant activity in beta-pancreatic cells so it is believed to treat DM. Snakehead fish has some efficacy including; has antinociceptive activity, accelerates wound healing, and is an anti-inflammatory. Objective; To determine the effect of snakehead fish extract and metformin on glycemic control of male rats with diabetes mellitus. Methods; This study used an experimental method with a post-test-only control group design. Results; Based on the Kruskal Walis test, it showed (p < 0.05) meaning that there was an effect of EIG administration on reducing blood glucose levels in rats, and there was a reduction of HbA1c but not significant. Conclusion; The combination of snakehead fish extract 300mg/kg BW and metformin 45 mg/kg BW was superior in lowering blood glucose and HbA1c levels compared to single therapy with snakehead fish extract or metformin.
Co-Authors Hendra Salim Hendy Million Yulizal, Ok