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All Journal The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Untung Sudomo
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Medicine & Pharmacology

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Do Hepatic Encephalopathy Patients Really Need a Low Protein in Their Diet Untung Sudomo; Syafruddin AR Lelosutan; Ruswhandi Ruswhandi; Nurul Akbar
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 8 ISSUE 2 August 2007
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/82200753-56

Abstract

Hepatic encephalopathy (HE) is an extra hepatic complication of liver cirrhosis. The clinical manifestation of HE is a reflection of a low-grade cerebral edema due to astrocyte swelling as a consequence of hyperammonia. HE mostly is induced by precipitating factors. Correcting these identifiable precipitating factors can alleviate this complication. In the past, liver cirrhosis patients were recommended to lower their protein intake. It was assumed that by limiting protein intake, the ammonia production would lower, which can lead to HE recovery. This approach, on the other hand, had worsened the nutritional status that already present in most patients with HE. There are some ways to overcome these problems without restricting protein intake including balance diet, using Branch Chain Amino Acids (BCAA), and frequent small portion diet.   Keywords: hepatic encephalopathy, astrocytes swelling, ammonia, liver cirrhosis, BCAA
Co-Authors Nurul Akbar Nurul Akbar Ruswhandi Ruswhandi Syafruddin AR Lelosutan