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The effects of phytosterol in low fat milk on serum lipid levels among mild-moderately hypercholesterolemic subjects Sukmaniah, Sri; Bardosono, Saptawati; Oetoro, Samuel; Permadhi, Inge; Lestarina, Leilani
Medical Journal of Indonesia Vol 17, No 1 (2008): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.486 KB) | DOI: 10.13181/mji.v17i1.294

Abstract

One of the most important risk factors for CHD is dyslipidemia, among others hypercholesterolemia or high LDL-cholesterol. Plant-sterols or phytosterols (PS) are among dietary factors known to lower blood cholesterol as part of therapeutic life-style changes diet. This study was aimed to evaluate the effect of PS properly solubilized in a-partly vegetable oil-filled low fat milk, on serum lipid levels in mild-moderate hypercholesterolemic subjects. Randomized, two-arm parallel control group trial was conducted at Department of Nutrition-University of Indonesia in Jakarta from June to November 2006. Each subject was randomly assigned to receive dietary life-style changes counseling plus 1.2 g phytosterol/day in low-fat milk (PS-group) or control group receiving the counseling alone for six weeks period. There were no significant changes of serum total and LDL-cholesterol of control group after a six week of dietary counseling (respectively 218.3 ± 18.6 mg/dL to 219.6 ± 24.3 mg/dL and 164.7±21.8 mg/dL to 160.0±26.4 mg/dL). There were a significant decreases of serum total and LDL-cholesterol (respectively p=0.01 and p=0.004) among subjects receiving PS after a six weeks observation period (respectively 233.5±24.6 mg/dL to 211.2±30.3 mg/dL and 176.9±24.7 mg/dL to 154.5±24.3 mg/dL). There was a significant difference in the LDL-lowering effects (p=0.024) among the PS-group after a six weeks (22.4±27.9 mg/dL) as compared to the control group (4.7±17.2 mg/dL). No significant changes were found on serum HDL-cholesterol and triglyceride levels in both groups. Although there was no significant difference found in daily nutrients intake between the-2 groups, however, significant reductions in body weight, body mass index and waist circumference were found only in the PS group (p=0.000; 0.000; 0.003, respectively). It is concluded that the lowering of total and LDL-cholesterol in those receiving life-style changes counseling plus 1.2 g PS daily for six weeks was significantly higher as compared to those of receiving counseling alone. (Med J Indones 2008; 17: 5-12) Keywords: TLC Diet, LDL-cholesterol, HDL-cholesterol, triglyceride, phytosterol, body mass index, waist-circumference
Effect of a six-month iron-zinc fortified milk supplementation on nutritional status, physical capacity and speed learning process in Indonesian underweight schoolchildren: randomized, placebo-controlled Bardosono, Saptawati; Dewi, Lestari E.; Sukmaniah, Sri; Permadhi, Inge; Eka, Andayani D.; Lestarina, Leilani
Medical Journal of Indonesia Vol 18, No 3 (2009): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (159.308 KB) | DOI: 10.13181/mji.v18i3.361

Abstract

Aim to evaluated the effect of milk supplementation enriched with iron and zinc on indicators of growth, physical capacity and cognitive performance in underweight school-children.Method Two-armed, randomized controlled double-blind trial was performed in several primary schools in Jakarta and Surakarta, Indonesia. A total of 245 underweight schoolchildren aged 7-9 years living in urban poor areas of Jakarta and Solo were randomly allocated to receive two cups of iron-zinc fortified-milk (n = 121) or non-iron-zinc fortified milk (n= 124) supplementation daily for six months. Biochemical indicators, anthropometric indices, physical capacity and cognitive performance were measured at before and after the supplementation.Results The study shows that between the fortified and non-fortified milk group, there was no significant different in haemoglobin increase (0.01 + 0.96 mg/dL versus 0.17 + 0.81 mg/dL) nor serum ferritin increase (12.77 + 25.50 mcg/dL versus 14.99 + 29.56 mcg/dL). Unexpectedly, decreased in serum zinc was found in both groups (3.01 + 3.24 mMol/dL and 3.12 + 3.71 mMol/dL). There was significant higher increment (P=0.045) in body weight among the fortified milk group (1.31 + 0.69 kg) as compared to the non-fortified group (1.13 + 0.69 kg). Consistently, there was significant increase (P=0.025) in the indicator of underweight (WAZ) among the fortified milk group (1.47 + 0.50) as compared to the non-fortified group (1.33 + 0.47). There was significant improvement (P=0.001) of cognitive performance, i.e. coding test-score among the fortified group (12.74 + 11.76) as compared to the non-fortified group (8.31 + 9.60), but there was no significant difference found in the improvement of physical capacity score in both groups (10323.77 + 9253.83 versus 8435.94 + 8824.55).Conclusion Among underweight schoolchildren aged 7-9 y, supplementation of milk fortified with iron and zinc can provide better growth, and better speed processing of learning ability. (Med J Indones 2009; 18: 193-202)Key words: Iron and zinc, underweight, growth, physical capacity, cognitive function, schoolchildren
Efek Bubuk Susu Kedelai terhadap Kadar Kolesterol LDL dan HDL Serum Wanita Perimenopause dengan Hiperkolesterolemia Retno Kuntarti; Sri Sukmaniah; Sri Widia A. Jusman
Majalah Sainstekes Vol 4, No 2 (2017): Desember
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (388.123 KB) | DOI: 10.33476/ms.v4i2.908

Abstract

Perimenopausal women is at risk of atherosclerosis as a result of the increase of LDL cholesterol level and the decrease of HDL cholesterol level.  Soy milk powder consumption may protect toward these risk factors. This purpose of study is to investigate the effects of 2x30 g/d soy milk flour for eight weeks on serum cholesterol LDL and HDL levels in hypercholesterolemic perimenopausal women. The 19 subjects received 2x30 g/d soy milk powder for eight weeks. LDL and HDL serum cholesterol levels were determined at 0, 4, 9 weeks. Dietary intakes were assesed using 1x24 hours food recall. Statistical analysis used t Test. After eight weeks intervention, Soy milk powder decreases significant (p less than 0.05) LDL cholesterol levels at the 4th  week (8.59 plus-minus 17.31%), and the8th week (7.81 plus-minus 11.32%). Soy milk powder can’t increase HDL cholesterol levels at the 4th and 8th weeks significantly.  Soy milk decrease significant the ratio of LDL to HDL (7,03 plus-minus 16,82%) at the 4th week. Consuming soy milk powder 2 x 30 g/d during eight weeks can reduce the LDL cholesterol level and LDL/HDL ratio significantly.
Hubungan antara Asupan Makronutrien dan Status Nutrisi Dengan Kekuatan Otot Pada Lansia di Panti Werdha Jakarta halim, Rita halim; Sukmaniah, Sri
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 8 No. 2 (2020): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (187.932 KB) | DOI: 10.22437/jmj.v8i2.10665

Abstract

Background: The decrease of muscle mass and strength in elderly people will affect the functional capacity and increase the risk of sarcopenia. One factor that can affect the loss of muscle mass and strength in elderly is the decrease in nutrition intake i.e macronutrient especially protein and branched chain amino acids (BCAA). The aim of this study is to examine the association between muscle strength intake with macronutrient intake and nutritional status in elderly people. Methods: The methodology of this research is a cross-sectional study with 52 elderly people from April-May 2016. Macronutrient intake is obtained from 2x24 hours food records. Anthropometric measurement is performed by using Seca electrodigital scale and knee height caliper. Blood sampling to measure prealbumin was performed after the subjects fasted for ± 8 hours, and muscle strength was measured with a Jamar’s handgrip dynamometer. Results: The results show significant possitive correlation between handgrip strength with energy intake( r=0,32 dan p=0,02) and carbohydrate intake (r=0,46 dan p=0,01). However, fat intake, protein intake, BCAA intake, serum prealbumin, and BMI have no correlation with handgrip strength. Conclusion: This study concludes that energy intake, especially from carbohydrate intake, can affect muscle strength in elderly. Keywords: macronutrient intake, nutritional status, serum prealbumin, muscle strenght