Garuda - Garba Rujukan Digital

p-Index From 2020 - 2025

0.659

P-Index

This Author published in this journals

All Journal Medical Journal of Indonesia Sari Pediatri Oto Rhino Laryngologica Indonesiana Cermin Dunia Kedokteran Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)

Saptawati Bardosono

Department Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta

Author-ID : 240837

Health Professions Medicine & Pharmacology Public Health

Published : 21 Documents Claim Missing Document

Claim Missing Document

Articles

1 2 3

Association between dietary intake of vitamin A, C, and E as antioxidants and cognitive function in the elderly at a nursing home Tani, Jowy; Widjaja, Ivan R.; Tedja, Irwin; Pratomo, Irandi P.; Siagian, Ira; Fahri, Indra; Amri, Zarni; Bardosono, Saptawati
Medical Journal of Indonesia Vol 16, No 4 (2007): October-December
Publisher : Faculty of Medicine Universitas Indonesia

As oxidative stress is considered one of the major mechanisms underlying degenerative changes, antioxidants from dietary sources, such as vitamin A, C, and E, may have protective effects against oxidative stress and thus be able to prevent or delay cognitive impairment in the elderly. This cross sectional study was designed to determine the association between dietary intake of vitamin A, C, and E and the presence of cognitive impairment in the elderly, along with other factors. Subjects included 36 residents from a nursing home in Jakarta, Indonesia. The data obtained including daily nutrition intake values one week prior to sampling converted from semi- quantitative food frequency questionnaire (SFFQ) results, Mini Mental State Examination (MMSE) scores, and anthropometrical measurement results. This study showed that while sex, age, education, nutritional status, and macronutrients intake were not significantly associated with presence of cognitive impairment, significant positive correlation existed between education and MMSE score (p=0.036, r=0.351). Higher vitamin A and vitamin C intake were shown to be significantly associated with lower incidence of cognitive impairment (p=0.022 and p=0.045, respectively). Moreover, vitamin C was shown to have significant positive correlation with MMSE score (p=0.031, r=0.359). However, the association between vitamin E and the presence of impairment was not significant (p=0.129). Higher intake of vitamin A and C may delay or prevent cognitive impairment in the elderly. Higher intake of vitamin C may contribute to better cognitive functioning. The findings may be explained by the two antioxidant vitaminsâ protective effects against neurode generative processes cause by oxidative stress. (Med J Indones 2007; 16:261-6)Keywords: antioxidant, vitamin A, vitamin C, vitamin E, cognitive impairment, the elderly

Relationship between plasma lipid profile and the severity of diabetic retinopathy in type 2 diabetes patients Rianita, Rianita; Bardosono, Saptawati; Victor, Andi A.
Medical Journal of Indonesia Vol 17, No 4 (2008): October-December
Publisher : Faculty of Medicine Universitas Indonesia

This study aimed to determine the relationship between plasma lipid profile and the severity of diabetic retinopathy in type 2 diabetes patients. A cross sectional study was done inÂ Ophthalmologic Clinic, Cipto Mangunkusumo General Hospital, Jakarta for 52 diabetic retinopathy (DR) patients. Data collected were demographic, life style, duration of diabetes, physical and antropometric examinations, fat, fatty acid and cholesterol intake, fasting plasma glucose, A1C, total-, LDL-,HDL-cholesterol and triglyceride level, and fundus examination. Statistical analysis was done using chi-square test to see the associations between plasma lipid profile and DR in type 2 diabetes patients. Subjects comprised of 20 males and 32 females diabetes patients with mean age of 53.8 Â± 5.2 years. As much as 53.8% had been diagnosed as DM for >10 years. The mean value of BMI was 24.1 Â± 3.3 kg/m2 and 38.5% were classified as obese I and II. The mean value of fasting plasma glucose was 157.5 Â± 71.8 mg/dL, and A1C was 9.1 Â± 2.4 %. For lipid profile, 40.4% had high total cholesterol level (>240 mg/dL), 34.6% had high and very high LDL-cholesterol level (â¥160 mg/dL), and 65.4% had normal HDL-cholesterol (40-60 mg/dL) and triglyceride level (<150 mg/dL). For the severity of retinopathy, 61.6% had severe non-proliferative diabetic retinopahy (NPDR) and proliferative diabetic retinopahy (PDR). In conclusion, there were no significant associations between plasma lipid profile and the severity of diabetic retinopathy. (Med J Indones 2008; 17: 221-5)Keywords: Fat intake, lipid profile, diabetic retinopathy

The effect of indigestible dextrin and phytosterol on serum LDL-cholesterol level on hypercholesterolemic subjects Then, Anna H.; Bardosono, Saptawati; Harahap, Indriati P.
Medical Journal of Indonesia Vol 18, No 2 (2009): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Aim To investigate the effects of indigestible dextrin 2x2.3g/day and phytosterol 2x0.6g/day provided for 6 weeks in lowering serum LDL-cholesterol levels amongs hypercholesterolemic subjects.Methods A randomized clinical trial, two pararel groups, double blinded and randomly assigned to each different group was done in 16 subjects per-group.Results Before the, intervention the level of LDL cholesterol of both ID and FS group were 158.81 Â± 17.74 mg/dL and 176.18 Â± 25.31 mg/dL, respectively. After the intervention there was a significant reduction in LDL cholesterol level in both groups, i.e. among the ID group by 20.93 Â± 12.65 mg/dL (13.24%) with p value of <0.001, while the reduction of LDL cholesterol level among the PS group was 21.87 Â± 28.76 mg/dL (11.21%) with p value of 0.008. However, the reduction of cholesterol level between the two groups did not show any significant difference.Conclusion Consuming indigestible dextrin 2x2.3g/day and 2x0.6g/day phytosterol (PS) for 6 weeks will have the same ability to decrease the serum cholesterol level in hypercholesterolemic subjects. (Med J Indones 2009; 18: 114-9)Key words: indigestible dextrin, phytosterol, cholesterol

The effects of phytosterol in low fat milk on serum lipid levels among mild-moderately hypercholesterolemic subjects Sukmaniah, Sri; Bardosono, Saptawati; Oetoro, Samuel; Permadhi, Inge; Lestarina, Leilani
Medical Journal of Indonesia Vol 17, No 1 (2008): January-March
Publisher : Faculty of Medicine Universitas Indonesia

One of the most important risk factors for CHD is dyslipidemia, among others hypercholesterolemia or high LDL-cholesterol. Plant-sterols or phytosterols (PS) are among dietary factors known to lower blood cholesterol as part of therapeutic life-style changes diet. This study was aimed to evaluate the effect of PS properly solubilized in a-partly vegetable oil-filled low fat milk, on serum lipid levels in mild-moderate hypercholesterolemic subjects. Randomized, two-arm parallel control group trial was conducted at Department of Nutrition-University of Indonesia in Jakarta from June to November 2006. Each subject was randomly assigned to receive dietary life-style changes counseling plus 1.2 g phytosterol/day in low-fat milk (PS-group) or control group receiving the counseling alone for six weeks period. There were no significant changes of serum total and LDL-cholesterol of control group after a six week of dietary counseling (respectively 218.3 Â± 18.6 mg/dL to 219.6 Â± 24.3 mg/dL and 164.7Â±21.8 mg/dL to 160.0Â±26.4 mg/dL). There were a significant decreases of serum total and LDL-cholesterol (respectively p=0.01 and p=0.004) among subjects receiving PS after a six weeks observation period (respectively 233.5Â±24.6 mg/dL to 211.2Â±30.3 mg/dL and 176.9Â±24.7 mg/dL to 154.5Â±24.3 mg/dL). There was a significant difference in the LDL-lowering effects (p=0.024) among the PS-group after a six weeks (22.4Â±27.9 mg/dL) as compared to the control group (4.7Â±17.2 mg/dL). No significant changes were found on serum HDL-cholesterol and triglyceride levels in both groups. Although there was no significant difference found in daily nutrients intake between the-2 groups, however, significant reductions in body weight, body mass index and waist circumference were found only in the PS group (p=0.000; 0.000; 0.003, respectively). It is concluded that the lowering of total and LDL-cholesterol in those receiving life-style changes counseling plus 1.2 g PS daily for six weeks was significantly higher as compared to those of receiving counseling alone. (Med J Indones 2008; 17: 5-12) Keywords: TLC Diet, LDL-cholesterol, HDL-cholesterol, triglyceride, phytosterol, body mass index, waist-circumference

Serum folate levels among healthy infants aged 6â8 months: relation to infantsâ nutritional status indicators and maternal knowledge-attitude-practice Ernawati, Tutik; Bardosono, Saptawati; Sekartini, Rini
Medical Journal of Indonesia Vol 20, No 2 (2011): May
Publisher : Faculty of Medicine Universitas Indonesia

Background: Vitamin B12 and folate deficiency can cause anemia which may lead growth and developmentÂ impairments. This study was aimed to determine serum folate levels among infants aged 6â8 months and the relationÂ to infantsâ nutritional indicators and maternal knowledge-attitude-practice about infant feeding.Methods: A crossâsectional design was implemented in infants aged 6â8 months and their mothers as respondents whoÂ met the study criteria. Data collected among the infants included sex, age, length, weight, intake of energy, protein andÂ folate (based on a oneâmonth semiâquantitative FFQ and a 24âhour food recall), serum folate and hemoglobin levels.Â Data collected among the mothers included age, education level, income based on average minimum monthly wage,Â knowledge, attitude and behavior concerning infantâs feeding, i.e. breast milk and complementary feeding practices.Results: This study found that the median of serum folate levels was 43.05 nmol/L with values ranging from 19.92 nmol/LÂ to 104.24 nmol/L. Serum folate level had a strong positive correlation with its related factors, protein and folate intake.Conclusions: Protein-folateârich complementay food should be provided to infants aged 6 months and over toÂ maintain serum folate level. (Med J Indones 2011; 20:138-42)Keywords: Folate, infants, nutrient intake, nutritional status

Effect of a six-month iron-zinc fortified milk supplementation on nutritional status, physical capacity and speed learning process in Indonesian underweight schoolchildren: randomized, placebo-controlled Bardosono, Saptawati; Dewi, Lestari E.; Sukmaniah, Sri; Permadhi, Inge; Eka, Andayani D.; Lestarina, Leilani
Medical Journal of Indonesia Vol 18, No 3 (2009): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Aim to evaluated the effect of milk supplementation enriched with iron and zinc on indicators of growth, physical capacity and cognitive performance in underweight school-children.Method Two-armed, randomized controlled double-blind trial was performed in several primary schools in Jakarta and Surakarta, Indonesia. A total of 245 underweight schoolchildren aged 7-9 years living in urban poor areas of Jakarta and Solo were randomly allocated to receive two cups of iron-zinc fortified-milk (n = 121) or non-iron-zinc fortified milk (n= 124) supplementation daily for six months. Biochemical indicators, anthropometric indices, physical capacity and cognitive performance were measured at before and after the supplementation.Results The study shows that between the fortified and non-fortified milk group, there was no significant different in haemoglobin increase (0.01 + 0.96 mg/dL versus 0.17 + 0.81 mg/dL) nor serum ferritin increase (12.77 + 25.50 mcg/dL versus 14.99 + 29.56 mcg/dL). Unexpectedly, decreased in serum zinc was found in both groups (3.01 + 3.24 mMol/dL and 3.12 + 3.71 mMol/dL). There was significant higher increment (P=0.045) in body weight among the fortified milk group (1.31 + 0.69 kg) as compared to the non-fortified group (1.13 + 0.69 kg). Consistently, there was significant increase (P=0.025) in the indicator of underweight (WAZ) among the fortified milk group (1.47 + 0.50) as compared to the non-fortified group (1.33 + 0.47). There was significant improvement (P=0.001) of cognitive performance, i.e. coding test-score among the fortified group (12.74 + 11.76) as compared to the non-fortified group (8.31 + 9.60), but there was no significant difference found in the improvement of physical capacity score in both groups (10323.77 + 9253.83 versus 8435.94 + 8824.55).Conclusion Among underweight schoolchildren aged 7-9 y, supplementation of milk fortified with iron and zinc can provide better growth, and better speed processing of learning ability.Â (Med J Indones 2009; 18: 193-202)Key words: Iron and zinc, underweight, growth, physical capacity, cognitive function, schoolchildren

Dietary iron intake, serum ferritin and haemoglobin levels, and cognitive development scores of infants aged 6â8 months Kusumadewi, Dian; Bardosono, Saptawati; Sekartini, Rini
Medical Journal of Indonesia Vol 20, No 1 (2011): February
Publisher : Faculty of Medicine Universitas Indonesia

Background: Iron deficiency during infancy may lead to negative effect on cognitive function and psychomotor development. This study aimed to investigate serum ferritin, haemoglobin level and its relation to cognitive development score in infants aged 6â8 months.Methods: This cross-sectional study was done on 76 infants recruited from several selected community health center in Kampung Melayu Village, Jatinegara Jakarta who had fulfilled the study criteria. Data collected consist of age, weight, height, head circumference, energy, protein and iron intake, serum feritin levels, haemoglobin levels and cognitive development score using Capute Scales method (Cognitive Adaptive Test/ Clinical Linguistic Auditory Milestone Scales/ CAT-CLAMS).Results: Among 74 infants aged 6-8 months, 73% had less dietary iron intake as compared to its RDA (7 mg/d), 18.9% were with serum ferritin less than normal value (20 Î¼g/L), and 56.7% with haemoglobin levels less than normal value (11 mg/dL). In relation to cognitive development score, this study revealed that the CAT score was significantly lower among subjects with hemoglobin value less than 11 mg/dL (p = 0.026).Conclusion: Early prevention of impaired cognitive development is urgently needed by providing iron-rich complementary foods to infants since 6 months (mo) old to maintain the normal level of hemoglobin. (Med J Indones 2011; 20:46-9)Keywords: cognitive score, ferritin, hemoglobin, infants

Health, nutrition and hydration status of Indonesian workers: a preliminary study in two different environmental settings Bardosono, Saptawati; Ilyas, Ermita
Medical Journal of Indonesia Vol 23, No 2 (2014): May
Publisher : Faculty of Medicine Universitas Indonesia

Background: Hydration status in the working environment of hot and conveniently cool may influence the health status of workers, including their hydration status. This study aimed to determine the health, nutrition and hydration status of workers in two different working environment, i.e. hot and conveniently cool environment.Methods: A cross-sectional comparative study was done on apparently healthy male subjects, age 25-45 years. Two groups of factory workers consisted ofÂ 39 subjects working in environment exposed directly to heat and the other doing administrative work in cool environment. Data on their health status (physical examination), weight, height, waist circumference, fat body composition, laboratory result, were collected. The data was presented as average value andÂ proportion; statistical analysis with unpaired-t (Mann-Whitney test) and chi-square test was used.Results: Subjects working in a hot environment were more prone to dehydrationÂ in comparison to their counterparts, as was shown by significantly higher values of several hydration status biomarkers: hemoglobin (15.6 vs 14.8 g/dL, p = 0.017), hematocrit (46 vs 44.5%, p = 0.040), blood viscosity (23 vs 12 mEq/L, p < 0.001), and blood sodium concentration (140 vs 138 mEq/L, p < 0.001). In contrast, subjects working in a conveniently cool environment who did more administrative tasks were physically less active, had significantly lower HDL-cholesterol level (43 vs 52.1 mg/dL, p = 0.005), higher body and visceral fat compositions (21.6 vs 17.6%, p = 0.008, and 10 vs 8%, p = 0.015, respectively) compared to their counterparts.Conclusion: Workers in hot and cool working environment are prone to nutrition- and health problems as well as dehydration, suggesting special attention to the provision of timely drinking water, and physical activity during working time.

Modified exorotation graft tension for tibial fixation in anterior cruciate ligament reconstruction: a randomized controlled trial Pontoh, Ludwig A.P.; Dilogo, Ismail H.; Bardosono, Saptawati; Lubis, Andri M.T.; Harahap, Alida R.; Pandelaki, Jacub; Hidayat, Mohammad
Medical Journal of Indonesia Vol 27, No 3 (2018): September
Publisher : Faculty of Medicine Universitas Indonesia

Background: The inability of anterior cruciate ligament reconstruction (ACLR) surgery to reduce tibial internal rotation causes many problems. A large tibial internal rotation will result in a patellofemoral pain syndrome. This study aimed to introduce a new technique of modified exorotation graft tension at tibial fixation to minimize endorotation, reduce tibial internal rotation, and prevent patellofemoral pain syndrome.Methods: This study was a randomized double-blind controlled clinical trial. ACL rupture patients underwent ACLR surgery between December 2014 and Februrary 2015. They were randomized to standard endorotation group or modified exorotation group. Hamstring autograft was used and fixed with an EndoButton® and bioabsorbable interference screw. Tibial tubercle to trochlear grove (TTTG) was used to evaluate rotation, whereas cartilage oligomeric matrix protein (COMP) was employed to analyze cartilage breakdown. The functional outcome was measured using the Kujala score to assess patellofemoral joint function. Evaluations were conducted before the surgery and at 6 months postoperation.Results: A total of 29 subjects were recruited. Sixteen subjects were allocated into the standard endorotation group, and 13 were assigned to the modified exorotation group. The exorotation group demonstrated better results than the endorotation group in all three parameters: TTTG (p=0.028), COMP (p<0.001), and Kujala score (p=0.015).Conclusion: A new technique of modified exorotation direction of graft tension for ACL reconstructive surgery at tibial fixation showed a significant reduction in tibial internal rotation and cartilage breakdown. The proposed method could significantly improve the functional outcome of those with total ACL rupture.

The effect of fiber-rich milk and equi-carbohydrate snack on glycemic and insulin response and satiety feeling Chandra, Dian N.; Bardosono, Saptawati
Medical Journal of Indonesia Vol 25, No 2 (2016): June
Publisher : Faculty of Medicine Universitas Indonesia

Background: Additional dietary fibers which can decrease the glycemic response by slowing down digestion whilst maintaining the available carbohydrate content is one approach of healthy diet. This study aimed to compare post-prandial glycemic and insulin response, hunger and satiety feeling after consuming fiber-rich milk compare with equi-carbohydrate food as morning snack in healthy adults.Methods: Cross-over study was conducted on 12 healthy subjects who fulfilled the criteria. Each test food was given after consuming standard breakfast. Venous blood samples for insulin and glucose level were taken before consuming test food, at 30, 60, 120, and 180 minutes after, and plotted against time to generate a curve. Hunger and satiety assessments were taken by visual analog scale (VAS) after each blood sampling.Results: In average, age was 30.8+4.3 years old, body mass index was 20.6±1.6 kg/m2. Seven of twelve subjects were females. There were significantly differences in postprandial glycemic response (p<0.001), insulin response (p=0.045) and hunger feeling (p=0.021) between the two foods. However, postprandial satiety feelings were not different significantly (p=0.357). The glycemic response area under the curve of fiber-rich milk was significantly lower than the equi-carbohydrate snack (p=0.010). Conclusion: Differences in glycemic and insulin response, and hunger feeling between two test foods, suggesting that fiber-rich milk can be used as an alternative snack for healthy adults. Further study is needed for the use of fiber-rich milk as an alternative snack for pre-diabetic patients.

Co-Authors Abd. Rasyid Syamsuri Achmad, Harry R. Agus Firmansyah Ali Sungkar Alida R Harahap, Alida R Andayani D. Eka Andi A. Victor Andri M.T. Lubis Angela BM Tulaar Anggreani, Lenny Anna H. Then Antonius H. Pudjiadi Arwin A.P. Akib, Arwin A.P. Atmarita Atmarita Audy Alexander, Ruth Basrowi, Ray W. Chandra, Dian Novita Chozie, Novie A. Devina, Almira Dewanto, Naomi E.F. Dharma, Rahayuningsih Dian Kusumadewi Diana Aulia Diana Sunardi Djajadiman Gatot Duki, M. I Zulkarnain Dwi Prasetyo Dwirestuti, Ratna Ermita Ilyas Gutama, Gutama Harahap, Alida R. Hindra I. Satari, Hindra I. Hutauruk, Syahrial Indra Fahri Indriati P. Harahap Inge Permadhi Ira Siagian Irandi Putra Pratomo Irwin Tedja Ismail Hadisoebroto Dilogo Ivan R. Widjaja Jowy Tani Kusnandi Rusmil Leilani Lestarina Lestari E. Dewi Lindawati Wibowo Ludwig A. Pontoh Lugyanti Sukrisman Marcel Prasetyo Marlinda Adham Mohammad Hidayat Munar Lubis Nani Dharmasetiawani Nasution, Dina Putri Noroyono Wibowo Padmonodewo, Suminarti Pandelaki, Jacub Ponpon S Idjradinata Prameswari, Natasya Putri, Atikah S. Rianita Rianita Rima Irwinda, Rima Rina A.C. Saragih, Rina A.C. Rini Hildayani Rini Sekartini Rulina Suradi, Rulina Samuel Oetoro Sari, Teny T. Sartika, Ratu Ayu D Siti B. Kresno Sitorus, Rita Soedjatmiko Soedjatmiko Sri R.S. Hadinegoro Sri Sukmaniah Sudigdo Sastroasmoro Surjadi Handoko, Iwan Syafitri, Inayah Tamin, Susyana Taralan Tambunan Teny T Sari1, Teny T Tutik Ernawati Widjaja Lukito Yulianti Wibowo, Yulianti Zakiudin Munasir Zanil Musa Zarni Amri

Title

Found 21 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 21 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 21 Documents
Search