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D Nilasari
Rheumatology Division of the Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo National Central General Hospital
Medicine & Pharmacology

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Systemic sclerosis in two generations family: a mother and offspring D Nilasari; Laniyati Hamijoyo; Yoga I Kasjmir; Bambang Setiyohadi
Indonesian Journal of Rheumatology Vol. 1 No. 1 (2009): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (188.963 KB) | DOI: 10.37275/ijr.v1i1.18

Abstract

Systemic sclerosis (SSc) is uncommon connective tissue disease characterized by a pathological thickening and tethering of the skin and involvement of internal organ (i.e gastrointestinal tract, heart, lungs, and kidneys). Systemic sclerosis seems to result from a multifactorial process (alteration of the immune system, genetic, and  environmental factors) but its pathogenesis remains unclear. A familial history of SSc represents an important risk factor for developing the disease.1 We describe two generations family who developed SSc.
Co-Authors Bambang Setiyohadi Laniyati Hamijoyo, Laniyati Yoga I Kasjmir