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Aminudin Sulaeman
Department of Chemistry, Institute Technology of Bandung, Jl Ganesha 10 Bandung
Chemical Engineering, Chemistry & Bioengineering Chemistry

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THE EFFECT OF CONCENTRATION OF CARRIER, pH AND TIME OF EXTRACTION ON SEPARATION'S FACTOR OF PENICILLIN G - PHENYL ACETATE BY REACTIVE EXTRACTION Imam Santoso; Buchari Buchari; M. Bachri Amran; Aminudin Sulaeman
Indonesian Journal of Chemistry Vol 7, No 2 (2007)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (130.06 KB) | DOI: 10.22146/ijc.21696

Abstract

The aim of this research is to study the effect of concentration carrier, pH and time of extraction on separation's factor of penicillin g - phenyl acetate by reactive extraction technique. The 10 mL  aqueous  solution with variation of  pH : 5, 6 contains 0.001 M penicillin G and 0.001 M phenyl acetate has been extracted with 10 mL n-butyl acetate contains dioctylamine as carrier. Variation concentration  of carrier were 0.000; 0.002; 0.004; 0.006 and 0.008 M. Variation time of extraction were 1, 5, 10, 15 and 20 min. The penicillin G and phenyl acetate that dissolved in organic phase ha been  reextracted with 10 mL aqueous with variation of pH : 7, 8. The optimum condition obtained as follow : concentration dioctylamine was 0.002M ; pH the first phase water was 5 and the second phase water was 8 ; and the time of extraction was 10 min.
Co-Authors Buchari Buchari Imam Santoso M. Bachri Amran