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Chulabhorn Mahidol
Chulabhorn Research Institute, Kamphaeng Phet 6 Road, Laksi, Bangkok 10210, Thailand
Chemical Engineering, Chemistry & Bioengineering Chemistry

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A New Polyketide from the Endophytic Fungus Penicillium chermesinum Cici Darsih; Vilailak Prachyawarakorn; Chulabhorn Mahidol; Somsak Ruchirawat; Prasat Kittakoop
Indonesian Journal of Chemistry Vol 17, No 3 (2017)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (299.473 KB) | DOI: 10.22146/ijc.22273

Abstract

A new polyketide derivative, 2-chloro-3,4,7-trihydroxy-9-methoxy-1-methyl-6H-benzo[c]chromen-6-one (1), was isolated from the endophytic fungus Penicillium chermesinum. The structure was established on the basis of UV, IR, HR-ESI MS, and 1D and 2D NMR experiments. The cytotoxicity against four cancer cell lines (HuCCA-1, HepG2, A-549, and MOLT-3) of compound 1 are 14.94-115.71 µM.
Co-Authors Cici Darsih Prasat Kittakoop Somsak Ruchirawat Vilailak Prachyawarakorn