Indonesian Journal of Chemistry
Vol 17, No 3 (2017)

A New Polyketide from the Endophytic Fungus Penicillium chermesinum

Cici Darsih (Research Unit for Natural Products Technology, Indonesian Institute of Sciences, Gading, Playen, Gunungkidul, Yogyakarta 55581, Indonesia)
Vilailak Prachyawarakorn (Chulabhorn Research Institute, Kamphaeng Phet 6 Road, Laksi, Bangkok 10210, Thailand)
Chulabhorn Mahidol (Chulabhorn Research Institute, Kamphaeng Phet 6 Road, Laksi, Bangkok 10210, Thailand)
Somsak Ruchirawat (Chulabhorn Graduate Institute, Chemical Biology Program, Kamphaeng Phet 6 Road, Laksi, Bangkok 10210, Thailand)
Prasat Kittakoop (Chulabhorn Graduate Institute, Chemical Biology Program, Kamphaeng Phet 6 Road, Laksi, Bangkok 10210, Thailand)

Article Info

Publish Date
30 Nov 2017

Abstract

A new polyketide derivative, 2-chloro-3,4,7-trihydroxy-9-methoxy-1-methyl-6H-benzo[c]chromen-6-one (1), was isolated from the endophytic fungus Penicillium chermesinum. The structure was established on the basis of UV, IR, HR-ESI MS, and 1D and 2D NMR experiments. The cytotoxicity against four cancer cell lines (HuCCA-1, HepG2, A-549, and MOLT-3) of compound 1 are 14.94-115.71 µM.

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Journal Info
Indonesian Journal of Chemistry
Website

Abbrev

ijc

Publisher

Universitas Gadjah Mada

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

Indonesian Journal of Chemistry is an International, peer-reviewed, open access journal that publishes original research articles, review articles, as well as short communication in all areas of chemistry including applied chemistry. The journal is accredited by The Ministry of Research, Technology ...