Catur Suci Sutrisnani
Program Studi Dokter Fakultas Kedokteran Unibraw Malang

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FAKTOR-FAKTOR YANG MELATARBELAKANGI MOTIVASI SESEORANG UNTUK MENGGUNAKAN SUNTIKAN SILICONE CAIR DI MALANG TAHUN 2001 Asmika, Asmika; Chuluq, Chusnul; Sutrisnani, Catur Suci
Jurnal Kedokteran Brawijaya Vol 21, No 2 (2005)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.276 KB) | DOI: 10.21776/ub.jkb.2005.021.02.7

Abstract

ABSTRACT Recently it has been reported that some women have suffered from illness complication as the effect of the use the liquid silicone to beautify themselves. Knowledge deprivation and eagerness to achieve complete beauty in an easy and cheap way makes them undertake a short cut which is getting the injection. The research is intended to know some factors underlying a person’s motivation to use liquid silicone injection in Malang in 2001. The research was a descriptive cross sectional method. The population was person who use liquid silicone injection in Malang 2001, this assume were 20 persons during the research (June – December 2001). This research showed that 15 respondents (75 %) of the samples knew the benefits of liquid silicone injection but did not know the effect of the injection, the education of this respondents were secondary and tertiary level 13 respondents (65 %), 6 respondents (30 %) of the sample working as beauticians, 6 respondents (30 %) of the samples having salary  Rp. 250.000,00 - Rp.500.000,00 per month,  9 respondents (45 %) of the samples feeling more beautiful and self confident after getting liquid silicone injection, 6 respondents (30 %) of the samples getting family permission, 12 respondents (60 %) of the samples having a social network to use the injection, 5 respondents (25 %) of the samples getting secondary health services and 4 respondents (20 %) of the samples getting
Precocious Puberty in a 4-year-old Child with 46,XX Disorder of Sexual Development: A Case Report Aini, Fitria Nugraha; Sutrisnani, Catur Suci
Jurnal KESANS : Kesehatan dan Sains Vol 5 No 3 (2025): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v5i3.500

Abstract

Introduction: Disorders of sex development (DSD) are congenital conditions in which there is a mismatch between chromosomal, gonadal, and phenotypic sex. Among 46,XX patients, the leading underlying disorder is congenital adrenal hyperplasia (CAH) secondary to 21-hydroxylase deficiency. Precocious puberty in 46,XX DSD is rarely documented, particularly in Indonesia. Case description: A four-year-old girl presented with atypical genitalia noted since birth with progressive enlargement resembling clitoromegaly. Physical examination revealed ambiguous genitalia, pubic hair development, and obesity. Laboratory results showed hyponatremia, markedly elevated estradiol, progesterone, and 17-hydroxyprogesterone, with suppressed gonadotropins. MRI demonstrated a uterus, ovary, cervix, vagina with clitoromegaly, and the absence of testicular tissue. Karyotyping confirmed 46,XX with negative SRY gene. Bone age was advanced, corresponding to an 11.5-year-old boy. Discussion: These findings indicated 46,XX DSD due to classical salt-wasting CAH with precocious puberty. In this patient, androgen excess may have induced early puberty through aromatization to estrogen. Pubertal development in DSD can be absent, delayed, incomplete, or prematurely triggered. Conclusion: This case highlights a rare presentation of precocious puberty in a child with 46,XX DSD. It underscores the inherent complexity of DSD, where misalignment between chromosomal, gonadal, and phenotypic sex creates substantial challenges for both diagnosis and clinical management.