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All Journal Jurnal Penelitian Farmasi Indonesia
Haris Nanda Prayoga
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Medicine & Pharmacology

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Isolasi dan Uji Aktivitas Antioksidan Senyawa Metabolit Sekinder dari Fraksi n-Butanol Daun Tin (Ficus carica L.) Varietas Brown Turkey Haris Nanda Prayoga; noveri rahmawati
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 1 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (377.68 KB) | DOI: 10.51887/jpfi.v8i1.625

Abstract

Tin leaf (Ficus carica L.) is one of the traditional medicines that has potential as an antioxidant. The purpose of this study was to isolate secondary metabolites and to test the antioxidant activity of pure isolates from the n-butanol fraction of tin leaves. Extraction was carried out by the fractionation method using n-hexane, ethyl acetate and n-butanol. Then the n-butanol fraction was separated by column chromatography and antioxidant activity was tested using the DPPH method. Pure isolate compounds labeled HNF-3, in the form of crystals, white with a melting point 189-191 ° C. Based on phytochemical examination data analysis, UV spectroscopy, FT-IR and 1H-NMR it can be concluded that the HNF-3 compound is a flavonoid glycoside group and has a moderate category of antioxidant activity with an IC50 value of 160.613 µg / mL.
Co-Authors Noveri Rahmawati