I Made Swastika
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DYNAMICS OF DENGUE HEMORRHAGIC FEVER INCIDENCE WITH SPATIO-TEMPORAL APPROACH IN MARITENGNGAE SUBDISTRICT, SIDENRENG RAPPANG DISTRICT, SULAWESI SELATAN PROVINCE, IN 2008-2009 I Made Swastika; Tri Baskoro Tunggul Satoto; Anis Fuad
Tropical Medicine Journal Vol 1, No 2 (2011): Tropical Medicine Journal
Publisher : Pusat Kedokteran Tropis

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1733.507 KB) | DOI: 10.22146/tmj.4570

Abstract

Introduction: Dengue Hemorrhagic Fever (DHF) causes 40% of world population at risk for infection, and 50 million people get infection with as many as 24,000 die every year. Incidence rate in Indonesia, particularly in Maritengngae Subdistrict, Sidenreng Rappang District, is increasing and needed to be controlled. Disease distribution has not been documented regionally. The dynamics of the incidence,that comprises the characteristics of the patient, environmental conditions, susceptibility of mosquitoes resulted from insecticide use, transovarial infectivity, and the incidence pattern were unknown.Objectives: To identify the dynamics of DHF incidence with spatio-temporal approach, includes gender, age, the habit of cleaning the water containers, house density, the density of water containers within the radius of 100 meters from the house of the patient, resistance of the mosquito, and transovarial transmission of Dengue virus.Methods: Subjects were DHF patients in Maritengngae Subdistrict. It was an epidemiological observational study with cross-sectional design and spatio-temporal approach to variables of the study, which included the patient characteristics (age, gender, habit of cleaning the water containers), environmental conditions (house density, water container density within 100 meter radius around the patient’s house), and vector conditions (resistance status to organophosphate insecticide, and transovarial transmission of Dengue virus).Results: Cases of DHF in Maritenggae Sub district, Sidenreng Rappang District, South Sulawesi decreased from 95 cases in 2008 to 38 cases in 2009, except in Kelurahan Majeling. Incidence distribution of DHF in 2008-2009 based on gender were not different (p=1.000), patients with age <15 years old were different from age ≥15 years (P=0.016 and p = 0.013), house density and density of water containers around the patient’s house were not different (p=0.829 and p = 0.538). The habit of cleaning water containers at the house was 43.84%. There were 1.94% of Aedes aegypti samples showed medium resistance (tolerance) status against organophosphat insecticide and 33.33% of samples showed transovarial transmission of Dengue virus. The highest of transovarial transmission occured in Kelurahan Majeling with transovarial transmission index of 100%.Conclusion: The transmission dynamic of DHF in Maritengngae sub district is not influenced by gender, house densities, water container densities, and the frequency of source reduction, but influenced by ages. Most of Ae. aegypti mosquitoes are still susceptible against organophosphate insecticides. The highest of transovarial transmission of dengue virus in Ae. aegypti in Kelurahan Majeling with Transovarial transmission index of 100% may contribute in the increasing of DHF cases in the Kelurahan Majeling in 2009.Keywords: dynamics, dengue, spatio-temporal, Ae. aegypti, Maritengngae.
Factors associated with oral Candida colonization in neonates at intensive care unit I Putu Wijana; Hendra Santoso; I Made Swastika
Paediatrica Indonesiana Vol 44 No 5 (2004): September 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (342.886 KB) | DOI: 10.14238/pi44.5.2004.188-92

Abstract

Background Oral candidiasis still has high prevalence andfrequently causes problems in the neonatal period.Objective To evaluate some factors associated with the occurrenceof oral Candida colonization in neonates.Methods A cross sectional study was performed at the IntensiveCare Unit, Neonatology Division, Department of Child Health,Medical School, Udayana University/Sanglah Hospital Denpasar,from November 2002 to April 2003. Eighty neonates were enrolled.Oral mucous swabs were obtained and examined for Candidacolonization using potassium hydroxide (KOH). Data were analyzedby prevalence ratio and logistic regression; a p value of <0.05 wasconsidered significant.Results The prevalence of oral Candida colonization was 55%(44/80). The colonization was significantly associated with age of>1 week, male sex, gestational age of <37 weeks, Apgar score of<7, birth weight of <1500 grams, oral mucous pH of <7, systemicantibiotic use, and steroid use by mother. Breastfeeding was aprotective factor. Correlation between variables using Spearmantest revealed correlation coefficient of <0.5. By logistic regres-sion, birth weight of <1500 grams (p=0.04) and systemic antibi-otic use (p=0.01) were significant associated factors of oralCandida colonization, while breastfeeding was a significant pro-tective factor (p=0.03).Conclusion Birth weight of <1500 grams and systemic antibioticuse were significant associated factors of oral Candida colonizationand breastfeeding was a significant protective factor of oral Candidacolonization in neonates