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All Journal Jurnal Kesehatan Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research
Vanny Syafitri
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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Gambaran Profil Lipid Pasien Perlemakan Hati Non-Alkoholik Vanny Syafitri; Arnelis Arnelis; Efrida Efrida
Jurnal Kesehatan Andalas Vol 4, No 1 (2015)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v4i1.234

Abstract

AbstrakPenyakit perlemakan hati non-alkoholik (non-alcoholic fatty liver disease) merupakan kondisi klinis yang sering ditemukan dalam bidang hepatologi. Salah satu faktor risiko penyakit ini adalah dislipidemia. Penelitian ini dilakukan untuk mengetahui distribusi frekuensi profil lipid pasien perlemakan hati non-alkoholik dengan dislipidemia. Penelitian dilakukan secara retrospektif di RS DR. M. Djamil Padang terhadap pasien perlemakan hati non-alkoholik dengan dislipidemia periode 2010–2013. Dari 118 pasien perlemakan hati non-alkoholik dengan dislipidemia hanya 43 subyek yang memenuhi kriteria penelitian. Rata-rata umur subjek penelitian pada laki-laki adalah 48,53±11,92 tahun dan perempuan 49,58±11,01 tahun. Subjek penelitian didominasi oleh perempuan dengan perbandingan 1,5:1 terhadap laki-laki. Didapatkan pasien hiperkolesterolemia sebanyak 61,82% , hipo-HDL-emia 86,05%, hiper-LDL-emia 44,19%, hipertrigliseridemia 55,81%. Kesimpulannya, pada perlemakan hati non-alkoholik ditemukan kadar kolesterol total dan trigliserida yang tinggi, kadar LDL yang normal serta kadar HDL yang rendah.Kata kunci: Profil lipid, perlemakan hati non-alkoholik, dislipidemiaAbstractNon-alcoholic fatty liver disease is a clinical condition that is often found in the field of hepatology. One of the risk factors for this disease is dyslipidemia. This study was conducted to determine distribution and frequency of the lipid profile patients non-alcoholic fatty liver with dyslipidemia.A retrospective study was conducted at DR. M. Djamil Padang hospital to patients of non-alcoholic fatty liver with dyslipidemia within 2010-2013. A total of 118 non-alcoholic fatty liver with dyslipidemia patients only 43 subjects who met the study criteria.The average age of the subjects were males 48.53±11.92 years and women 49.58±11.01 years. Subject is dominated by women against men with 1.5:1 ratio. This study observed that patient with hypercholesterolemia as much as 61.82%, hypo-HDL-emia 86.05%, hyper-LDL-emia 44.19%, hypertriglyceridemia 55.81%.It can be concluded patient of non-alcoholic fatty liver disease with dyslipidemia has high total cholesterol and triglyceride levels, normal LDL levels and low HDL levelsKeywords:Lipid profile, non-alcoholic fatty liver disease, dyslipidemia
Catamenial Pneumothorax in a Patient with Adenomyosis: A Case Report on a Successful Multidisciplinary Approach with Pleurodesis and Hormonal Therapy Vanny Syafitri; Suyastri
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 11 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i11.1423

Abstract

Background: Catamenial pneumothorax, a rare manifestation of thoracic endometriosis syndrome (TES), presents a significant diagnostic and therapeutic challenge. It is characterized by recurrent spontaneous pneumothorax occurring in temporal relation to menstruation in women of reproductive age. The underlying pathophysiology is complex, often involving the ectopic presence of endometrial tissue within the thoracic cavity. Coexisting pelvic pathologies, such as adenomyosis, may be associated, further complicating the clinical picture. Case presentation: We present the case of a 38-year-old woman with a four-month history of recurrent, right-sided pneumothorax, with symptoms consistently commencing 24 to 48 hours prior to the onset of her menstrual cycle. Initial investigations, including high-resolution computed tomography of the thorax performed between menstrual cycles and microbiological analysis for tuberculosis, were unremarkable. The diagnosis of catamenial pneumothorax was established based on the distinct cyclical pattern of her symptoms. A subsequent gynecological evaluation, prompted by a history of secondary dysmenorrhea and menorrhagia, revealed uterine adenomyosis via transvaginal ultrasonography. The patient was managed through a collaborative, multidisciplinary approach involving pulmonology, thoracic surgery, and gynecology. Treatment consisted of chemical pleurodesis with doxycycline, administered via a chest tube, followed by continuous hormonal suppression therapy with oral progestin (2 mg/day). Conclusion: This case highlights the critical importance of maintaining a high index of suspicion for catamenial pneumothorax in women of reproductive age presenting with recurrent pneumothorax. A successful outcome was achieved through a coordinated, multidisciplinary strategy combining definitive pleural symphysis via pleurodesis with systemic hormonal therapy to suppress the underlying endometriotic process. This dual approach effectively prevented pneumothorax recurrence over a 12-month follow-up period, underscoring its efficacy in managing this complex condition.
Catamenial Pneumothorax in a Patient with Adenomyosis: A Case Report on a Successful Multidisciplinary Approach with Pleurodesis and Hormonal Therapy Vanny Syafitri; Suyastri
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 11 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i11.1423

Abstract

Background: Catamenial pneumothorax, a rare manifestation of thoracic endometriosis syndrome (TES), presents a significant diagnostic and therapeutic challenge. It is characterized by recurrent spontaneous pneumothorax occurring in temporal relation to menstruation in women of reproductive age. The underlying pathophysiology is complex, often involving the ectopic presence of endometrial tissue within the thoracic cavity. Coexisting pelvic pathologies, such as adenomyosis, may be associated, further complicating the clinical picture. Case presentation: We present the case of a 38-year-old woman with a four-month history of recurrent, right-sided pneumothorax, with symptoms consistently commencing 24 to 48 hours prior to the onset of her menstrual cycle. Initial investigations, including high-resolution computed tomography of the thorax performed between menstrual cycles and microbiological analysis for tuberculosis, were unremarkable. The diagnosis of catamenial pneumothorax was established based on the distinct cyclical pattern of her symptoms. A subsequent gynecological evaluation, prompted by a history of secondary dysmenorrhea and menorrhagia, revealed uterine adenomyosis via transvaginal ultrasonography. The patient was managed through a collaborative, multidisciplinary approach involving pulmonology, thoracic surgery, and gynecology. Treatment consisted of chemical pleurodesis with doxycycline, administered via a chest tube, followed by continuous hormonal suppression therapy with oral progestin (2 mg/day). Conclusion: This case highlights the critical importance of maintaining a high index of suspicion for catamenial pneumothorax in women of reproductive age presenting with recurrent pneumothorax. A successful outcome was achieved through a coordinated, multidisciplinary strategy combining definitive pleural symphysis via pleurodesis with systemic hormonal therapy to suppress the underlying endometriotic process. This dual approach effectively prevented pneumothorax recurrence over a 12-month follow-up period, underscoring its efficacy in managing this complex condition.
Co-Authors Arnelis Arnelis Efrida Efrida Suyastri