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Ernawaty Tamba
Universitas Kristen Krida Wacana
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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analisis respon imunitas terhadap infeksi sars-cov-2 pada manusia Nainggolan, Edward Anderson; Tamba, Ernawaty; Susilowati, Rina Priastini
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.2998

Abstract

Understanding the immune response to COVID-19 is critical to help develop appropriate management. Understand the description and response of the immune system that is formed in humans through COVID-19 infection. Conduct a critical review of research journals on the immune response to SARS-CoV-19. Search for articles in research journal databases using the keywords COVID-19, SARS-CoV-2, and Immunity. COVID-19 patients have increased serum cytokine levels (TNFα, IL-2, IL-6, IL-10, IFNγ) compared with healthy patients. IL-6, IL-10, and CRP increased significantly with disease severity. The number of T cells decreases in COVID-19 patients, especially those who are more severe. There were no significant differences in antibody titers based on gender, age, or BMI in post-vaccine individuals. Smokers had significantly lower antibody titers after the second dose of vaccination. COVID-19 patients experience a decrease in the number of lymphocytes and an increase in CRP and cytokines such as TNFα, IL-2, IL-6, IL-10, and IFNγ, especially in severe cases. A positive correlation exists between CRP and IL-10. The number of T cells such as CD4+T and CD8+T also decreases in COVID-19 patients, especially those who are more severe. This could be a diagnostic and prognostic marker for COVID-19.
Risk Factors for Urinary Incontinence in the Elderly Regina, Kezia; Tamba, Ernawaty; Soesanto, Aries
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3145

Abstract

Individuals aged sixty years or older who require more care are referred to as seniors. Urinary incontinence in the elderly is a common problem. Uncontrolled urine production is known as urinary incontinence. Elderly people often experience this health problem. As we age, pelvic muscles weaken, resulting in changes in the anatomical function of the urinary tract organs and an increased risk of urinary incontinence. The aim of the research is to review related research on risk factors for urinary incontinence in the elderly. This research uses literature study. Where using a search for journals in Indonesian and English for 2013 - 2023 which was carried out using the WHO, PubMed, NCBI databases with the keywords Urinary incontinence in the elderly and found 10 journals selected according to the inclusion criteria with elderly subjects ≥ 45 years, cross sectional design and descriptive. The results show that urinary incontinence in the elderly has a significant relationship with risk factors for urinary incontinence such as diabetes, smoking, vaginal delivery and quality of life in the elderly. It can be concluded that there is a relationship between the two variables and most studies show that urinary incontinence is an important factor that can cause stress in the elderly.  
Description of the Level of Knowledge and Behavior of Type Two Diabetes Mellitus Patients Regarding Diabetic Foot at Koja Regional Hospital in June 2023 Tamba, Ernawaty; Bo, Alexandra Giacintya Bulan; Hamka, Aldo Muhammad; Mustamu, Swesty Bian; Suryawati, Esther
Jurnal MedScientiae Vol. 2 No. 3 (2023): Desember
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i3.3112

Abstract

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. In the Southeast Asia region, Indonesia is ranked 3rd with a prevalence of 11.3%. Previous studies have shown that the level of knowledge and behavior of type 2 diabetes mellitus patients regarding diabetic foot is still inadequate. This study aims to describe the level of knowledge and behavior of patients with type 2 diabetes mellitus regarding diabetic foot. The research design is descriptive with a cross-sectional approach. The reachable population for this study were all type two diabetes mellitus patients at Koja Hospital who the researchers could meet when conducting the study in June 2023. The sampling technique used was purposive sampling with a sample size of 40 patients. The research subjects were 40 people with type 2 Diabetes Mellitus. The results showed that in terms of knowledge, 50% of sufferers had a high level of knowledge. However, negative behavior is more dominant with a percentage of 57.5%. Although the level of knowledge and type two diabetes mellitus patients about diabetic feet at Koja Hospital in June 2023 is still high, patient behavior is still low, so it is necessary to train and empower health service providers to deliver adequate health messages regarding the prevention of diabetic feet
Co-Authors Bo, Alexandra Giacintya Bulan Hamka, Aldo Muhammad Mustamu, Swesty Bian Nainggolan, Edward Anderson Regina, Kezia Soesanto, Aries Suryawati, Esther Susilowati, Rina Priastini