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LITERATURE REVIEW : PENGARUH KONSUMSI KOPI TERHADAP KADAR KOLESTEROL PADA PENGKONSUMSI KOPI Anjelia Krispila; Donna Novina Kahanjak; Dian Mutiasari
Jurnal Kedokteran Universitas Palangka Raya Vol 10 No 2 (2022): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v10i2.5522

Abstract

Cholesterol is a complex problem for humans when LDL levels dominate causing heart disease and hypertension as a result of atherosclerosis. Prevalence in the United States adults has increased cholesterol levels > by 12%. Central Kalimantan cholesterol sufferers data reached 54.2%. Cholesterol 2/3 is produced by the liver while 1/3 is absorbed by the digestive system from the food consumed. Coffee does not contain cholesterol, but coffee contains cafestol and fat- soluble kahweol, often called diterpenes. The purpose of this review is to determine the effect of coffee on increasing cholesterol levels. This study uses a systematic review approach with the keywords coffee, cholesterol levels, and the effect of coffee consumption, with the PRISMA method. From the search results, obtained 14 journals discussing the effect of coffee consumption on cholesterol levels and how much coffee consumption can affect cholesterol levels, and the effect of coffee consumption on LDL levels. A total of 12 journals (85.2%) stated that there was a significant effect while 2 journals (14.2%) stated that there was no significant effect. As for the results of a literature review, it can be concluded that there is an effect of coffee consumption on cholesterol levels, the amount of coffee consumption that can affect cholesterol levels, and the effect of coffee on LDL levels
Uji aktivitas antibakteri ekstrak etanol daun sungkai (Peronema canescens Jack) terhadap pertumbuhan Escherichia coli dengan metode difusi cakram Kirby-Bauer Desta Fransisca; Donna Novina Kahanjak; A Frethernety
Jurnal Pengelolaan Lingkungan Berkelanjutan (Journal of Environmental Sustainability Management) JPLB, Vol 4, No 1 (2020)
Publisher : Badan Kerjasama Pusat Studi Lingkungan (BKPSL) se-Indonesia bekerjasama dengan Pusat Penelitian Lingkungan Hidup IPB (PPLH-IPB)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36813/jplb.4.1.460-470

Abstract

Diarrhea is a serious and dangerous condition that could be caused by Escherichia coli. Sungkai is a plant that easily could be found in Indonesia, especially in Central Borneo. The young leaf of sungkai usually used as traditional medicine and potentially as an antibacterial. Aim of this study was to determine the antibacterial activity from the ethanol extract of sungkai (Peronema canescens Jack) leaf to inhibit the growth of E. coli, examined by Kirby-Bauer’s disc method. Post-test only control group design was the method used in this study. The ethanol extract of sungkai (P. canescens) leaf was tested with various concentration (25%, 50%, 75% and 100%). The results showed that the E. coli’s growth could be inhibited by ethanol extract of sungkai (P. canescens) leaf with a concentration of 25%, 50%, 75% and 100%, proved by 3,75 mm, 3,5 mm, 3,5 mm and 7,75 mm inhibition zone in each of concentration sequentially, with the effective concentration of 25%. It is concluded that the ethanol extract of sungkai (P. canescens) leaf could inhibit the growth of E. coli. Further research should be developed to determine the minimum levels needed to obtain the antibacterial activity of sungkai extract.