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All Journal Media Kesehatan Masyarakat Indonesia PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia)
Akrom Akrom
University of Ahmad Dahlan
Materials Science & Nanotechnology Public Health

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The Effect of Black Cumin Seed Oil on Alanine Aminotransferase Levels which are Influenced by Nutritional Status in Active Smokers Arif Santoso; Titiek Hidayati; Akrom Akrom; Laela Hayu Nurani
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 18 No. 02 Desember 2021
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v18i2.13256

Abstract

Black cumin seed oil (BCSO) has the main compound thymoquinone which is thought to have hepatoprotective activity through an antioxidant mechanism. Exposure to cigarette smoke can cause cellular oxidative stress which is the key to the inflammatory process of liver cells and an increase in the activity of the Alanine aminotransferase (ALT) enzyme. Vitamin C and folic acid are nutrients that affect ALT levels through antioxidant activity. The main objective of this study was to see the effect of BCSO administration on ALT levels which were influenced by the intake of vitamin C and folic acid in healthy respondents who were active smokers for 30 days. This study used a single-blind Randomized Controlled Trial (RCT) method, with a total of 39 test subjects divided into four groups. Group 1 received 3x1 placebo, group 2 received BCSO 3x1, group 3 received BCSO 3x2, group 4 received BCSO 3x3. Investigation based on the ANOVA test, it turned out that there was no significant difference in the mean ALT levels in both the placebo group and the treatment group with p value = 0.452. For the p value of the intake of vitamin C and folic acid were 0.359 and 0.669, respectively. Based on the results of the study showed that the administration of BCSO for 30 days had no significant effect on the average activity of ALT in healthy active smokers and there was no significant difference in the intake of vitamin C and folic acid.
Supports and Barriers Regarding The Iron-Folic Acid Supplementation Adherence Level in Anemic Pregnant Women: Indonesian’s Perspective Rizka Novia Atmadani; Akrom Akrom; Dhea Ananda; Laila Yoga Saputri; Alvina Arum Puspitasari; Siti Urbayatun
Media Kesehatan Masyarakat Indonesia Vol. 20 No. 2: JUNE 2024
Publisher : Faculty of Public Health, Hasanuddin University, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30597/mkmi.v20i2.32569

Abstract

Anemia is a worldwide public health issue that affects various groups in low, middle, and high-income nations. Anemia is linked to pregnancy and is influencing poor cognitive and motor development outcomes in children. A recommended intervention to reduce anemia prevalence during pregnancy is the universal administration of Iron-Folic Acid (IFA) supplements. This study investigated supports and barriers regarding iron-folic acid supplementation adherence levels in pregnant women recorded in public health centers in Malang, Indonesia. This research was conducted using qualitative methods with in-depth interviews using semi-structured open-ended questions from July to September 2023. Twenty-five participants from four public health centers was included. The interview guide's content was developed using World Health Organization’s framework as well as other pertinent themes. Data analysis was processed from verbal record transcription, generating the codes into the outcomes. Five main themes with a total of eleven subthemes were highlighted from interview process. These themes was further classified into barriers and supports. Side effect, forgetfulness, boredom, laziness, and insufficient understanding of disease recorded as barriers. In contrast, husband and family support, health care team motivation, affordability of access, knowledge and education background included in supports. These findings enlighten the barriers encountered by the pregnant women in IFA supplementation adherence. However, the effectiveness of treating anemia during pregnancy might be influenced by fundamental elements that support IFA supplementation adherence. Therefore, to tackle the this issue, the pregnant women requires a proper therapy and all key points mentioned in support group must be applied.
Co-Authors Alvina Arum Puspitasari Arif Santoso Dhea Ananda Laela Hayu Nurani Laila Yoga Saputri Rizka Novia Atmadani Siti Urbayatun Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati