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All Journal Indonesian Journal of Cardiology
Alexander Edo Tondas
Unknown Affiliation
Health Professions Medicine & Pharmacology

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Traumatic Coronary Artery Dissection as A Potential Cause of Acute Myocardial Infraction in Motorcycle Accident Tondas, Alexander Edo; Tandri, Fredy; Zulkarnain, Edrian
Jurnal Kardiologi Indonesia Vol 43 No 1 (2022): Indonesian Journal of Cardiology: January - March 2022
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1140

Abstract

Background: Chest pain in blunt chest trauma can be caused by various intrathoracic injuries. Pneumothorax, hemothorax, and rib fractures are commonly seen in the emergency department. Although cardiac involvement is very rare, the probability should not be excluded. Case Illustration: A-31-years-old male who complained of chest pain and diaphoresis was brought to the emergency department after a high-speed motorcycle collision. Chest X-ray revealed no abnormality but a 12-lead Electrocardiogram (ECG) demonstrated ST-segment elevation in lead I, AvL, V2-6, and atrial fibrillation. Because of the unusual presentation, the decision was to proceed with percutaneous coronary intervention (PCI). Coronary Angiography detected a thrombus at proximal LAD and spiral dissection at mid LAD (TIMI 2 Flow). After the procedure, he was transferred to the High Care Unit. Conclusion: Following blunt chest trauma, chest pain in the setting of a vehicle collision can be caused by dissection of the coronary artery. Prompt cardiac workup (ECG, cardiac enzyme, and echocardiography) must be done in a highly suspected patient.
Perbandingan dua aplikasi penapis fibrilasi atrium berbasis ponsel cerdas pada populasi Indonesia Tondas, Alexander Edo; Halim, Rolando Agustian; Felani, Muhammad Rizki; Caesarani, Fianirazha Primesa; Puspita, Indah; Toruan, Mangiring Lumban
Jurnal Kardiologi Indonesia Vol 42 No 1 (2021): Indonesian Journal of Cardiology: January - March 2021
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1066

Abstract

Background: Due to its adverse outcomes and thromboembolic complications, early detection of atrial fibrillation (AF) is advisable in the general population. This study aims to compare the diagnostic ability of two distinct method in smartphone application format, namely : AliveCor KardiaMobile and FibriCheck. Methods: This study was conducted in Mohammad Hospital General Hospital Palembang with convenience sampling of 170 participants aged 18 years or older. The subjects underwent Fibricheck and KardiaMobile recordings followed by 12 lead electrocardiogram read by board-certified cardiologist as the diagnostic standard. Results: After the exclusion of previous pacemaker implantation (n=7), 163 patients were included in the study. The mean age was 51±15 years with gender distribution of 74.8% men and 25.2% women. Most of the subjects were asymptomatic (87.1%) with mean blood pressure of 130/80 mmHg. The Fibricheck readings showed sensitivity of 73% and specificity of 93%, meanwhile Kardiamobile was able to detect AF with sensitivity of 77% and specificity of 98%. Conclusion: In our study, KardiaMobile demonstrated overall greater sensitivity and specificity when compared to FibriCheck. However, KardiaMobile requires an external metal sensor that must be puchased separately. To the best of our knowledge, this is the first study to directly compare both methods in the Indonesian population.
Predictive Value of Bazett-Corrected QTc for Chemotherapy-Induced Cardiotoxicity in Breast Cancer: A Retrospective Cohort Study Lerista, Maria; Soniya, Firinda; Salsabila, Zeta Reihan; Putra, Justian Ananda; Agustine, Vania; Banun, Syahri; Felani, Muhammad Rizky; Puspita, Indah; Tondas, Alexander Edo
Jurnal Kardiologi Indonesia Online First
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1896

Abstract

Background : Cardiotoxicity remains a major concern in breast cancer patients receiving anthracycline-based chemotherapy. Meanwhile, prolongation of the QTc interval has been associated with an increased risk of torsades de pointes; however, the clinical evidence for its role as a predictor of subclinical cardiotoxicity remains limited. This study aims to evaluate the association between Bazett-corrected QTc and the incidence of subclinical left ventricular dysfunction, as measured by strain echocardiography. Methods : This single-center retrospective cohort study was conducted at Dr. Mohammad Hoesin General Hospital, Indonesia (January 2022–December 2023). Female breast cancer patients aged ≥18 years who received anthracycline or non-anthracycline chemotherapy and completed baseline and third-cycle echocardiography were included. QTc was measured from 12-lead ECGs before and after chemotherapy using Bazett’s formula. Subclinical cardiotoxicity was defined as a >15% relative reduction in global longitudinal strain (GLS) from baseline. Logistic regression and ROC analyses assessed the predictive value of baseline QTcB. Result : In 32 breast cancer patients on anthracycline therapy (mean age 49.5 ± 9.0 years) were analyzed; 59.4% developed subclinical cardiotoxicity. Prolonged baseline QTcB, older age, and obesity were significantly associated with subclinical cardiotoxicity (p < 0.05). In multivariate analysis, QTcB remained an independent predictor (OR = 21.09; 95% CI: 0.979–454.4; p = 0.05). ROC analysis showed moderate discrimination (AUC = 0.717; 95% CI: 0.50–0.92; p = 0.04). Conclusion : Prolonged QTc appears to be a promising predictor of subclinical cardiotoxicity with fair diagnostic accuracy. However, it should be considered alongside other modalities. Further studies with larger populations are needed to control for other risk factors.
Co-Authors Agustine, Vania Banun, Syahri Caesarani, Fianirazha Primesa Felani, Muhammad Rizki Felani, Muhammad Rizky Halim, Rolando Agustian Indah Puspita, Indah Lerista, Maria Putra, Justian Ananda Salsabila, Zeta Reihan Soniya, Firinda Tandri, Fredy Toruan, Mangiring Lumban Zulkarnain, Edrian