Kuldeep Dhama
Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India

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Bibliometric analysis of the top 100 most cited studies in apolipoprotein E (ApoE) research Tauseef Ahmad; Kuldeep Dhama; Ruchi Tiwari; Wanpen Chaicumpa; Jin Hui
Narra J Vol. 1 No. 1 (2021): April 2021
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narraj.v1i1.2

Abstract

The apolipoprotein E (ApoE) is a glycoprotein which plays a vital role in different inflammatory conditions and in the catabolism of lipids and triglycerides. The aim of this study was to identify and evaluate the top 100 most cited studies on ApoE research. A bibliometric study was conducted. On January 18, 2021, studies published on ApoE were searched in the Web of Science Core Collection database without any limitations. The obtained data were analyzed for a number of attributes using HistCiteTM and VOSviewer software. The search yielded a total of 16,242 results. Of the total retrieved results, the top 100 most cited studies were selected. The top 100 most cited studies on ApoE were published from 1977 to 2017 and were cited 86,181 times. Single study citations ranged from 426 to 6,327. The studies were published in 41 journals authored by 589 authors. The study “Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families” was cited 6,327 times. Mahley RW, Roses AD, and Saunders AM were the most prolific authors who published ten studies each. Most of the studies were published in Proceedings of the National Academy of Sciences of the United States of America. A total of 151 institutions were involved, and the USA was the most productive country. Our finding provides valuable insight on ApoE research which may be useful for researchers, academia, and funding agencies to identify new future research domains.
SARS-CoV-2 and Orientia tsutsugamushi co-infection in a young teen, Nepal: Significant burden in limited-resource countries in Asia? Anup Bastola; Ranjit Sah; Sagar K. Rajbhandari; Runa Jha; Zareena Fathah; Bimal S. Chalise; Bikesh Shrestha; Rajesh K. Shah; Pujan Balla; Richa Nepal; Bipin Adhikari; Ali A. Rabaan; Kuldeep Dhama; Alfonso J. Rodriguez-Morales
Narra J Vol. 1 No. 2 (2021): August 2021
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narraj.v1i2.34

Abstract

Scrub typhus is caused by Orientia tsutsugamushi, transmitted through bites of infected chiggers (larval mites). During the coronavirus disease 2019 (COVID-19) pandemic, reports of co-infections with endemic pathogens are increasing around the world. Disease with similar clinical presentation may mask other disease diagnosis and increase the morbidity and mortality of the patients. We report co-infection between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and O. tsutsugamushi in a patient in Nepal presenting with fever, headache, retro-orbital pain, generalized body ache, and knee joints pain with a history of dry cough and dyspnea at night. Since scrub typhus is prevalent and considerate as one of the public health consents in Asian countries and the possible overlapping clinical manifestation with other infections including COVID-19, a further investigation required to determine the burden of SARS-CoV-2 and O. tsutsugamushi co-infection in scrub typhus-endemic countries in Asia.
Hepatitis E virus in pigs and the environment: An updated review of public health concerns Tauseef Ahmad; Hui Jin; Kuldeep Dhama; Mohd. Iqbal Yatoo; Ruchi Tiwari; Muhammad Bilal; Manish Dhawan; Talha B. Emran; Jeehan H. Alestad; Hatem M. Alhani; Habib K. BinKhalaf; Ali A. Rabaan
Narra J Vol. 2 No. 2 (2022): August 2022
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v2i2.78

Abstract

Hepatitis E virus (HEV) is an important public health problem and is responsible for both acute and chronic viral hepatitis. Public health implications of HEV are derived from its transmission route, either water-borne or food-borne, and its zoonotic potential. Not only in developing countries, but HEV cases are also found in a high number in developed countries. The spread of HEV to the environment might pollute surface waters, which could act as the source of infection for both humans and animals. Identification of the virus in animal products suggests the circulation of HEV within water and food chains. High seroprevalence and circulation of HEV in livestock, in particular pigs, as well as in environmental samples warrants further investigation into pig markets. HEV virulence in different environments and meat supply chains could shed light on the possible sources of infection in humans and the degree of occupational risk. The purpose of this review is to discuss HEV infections with an emphasis on livestock- and environment-related risk factors, and food-borne, water-borne, and zoonotic transmissions.
Ramadan and Eid al-Fitr: Population movement, mass gathering and escalating of COVID-19 – A perspective from Indonesia Dian Sidik Arsyad; Firzan Nainu; Abram L. Wagner; Kuldeep Dhama
Trends in Infection and Global Health Vol 1, No 1 (2021): June 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i1.22421

Abstract

In Indonesia, the most populous Moslem-majority country, despite the possibility of underreported coronavirus disease (COVID-19) cases, 6,248 confirmed cases and 535 deaths have been recorded. With upcoming Ramadan and Eid al-Fitr, between 18-23 million of Indonesians may move from urban locations (with high counts of COVDI-19) to rural areas with fewer cases currently but less laboratory capacity to diagnose cases. This review summaries the current situation of CO.VID-19 in Indonesia and discusses the possible impacts of mass population movement, Ramadan-related activities, and Eid al-Fitr celebration days on COVID-19 transmission in the country.