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All Journal Jurnal Ilmu Alam dan Lingkungan
Sry Sukmawaty
Departemen Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Hasanuddin, Makassar 90245 Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Immunology & microbiology Veterinary

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Efektivitas Ekstrak Daun Eceng Gondok Eichornia crassipes Sebagai Bahan Antikanker pada Sel Tumor MCF-7 dengan Metode In Vitro dan In Silico Eva Johannes; Andi Ilham Latunra; Mustika Tuwo; Sry Sukmawaty
Jurnal Ilmu Alam dan Lingkungan Vol. 12 No. 1 (2021): Jurnal Ilmu Alam dan Lingkungan
Publisher : Universitas Hasanuddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jal.v12i1.13095

Abstract

The use of water hyacinth Eichhornia crassipes bioactive compounds has been developed, including as an anti-cancer base material. This study aims to examine the potential of water hyacinth leaf extract on MCF-7 tumor cells with the MTT method and the affinity of the water hyacinth leaf compound using molecular docking methods. The results showed the effect of water hyacinth leaf extract on MCF-7 cancer cell death due to the active compounds stigmasterol and phytol, while the docking results showed the best binding affinity value on stigmasterol and its receptor 1QR1 which was -9.4.
Co-Authors Andi Ilham Latunra Eva Johannes Mustika Tuwo