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PERAN GLUKOSAMIN PADA OSTEOARTRITIS Utami, Pratiwi; Kalangi, Sonny J.R.; Pasiak, Taufiq
Jurnal Biomedik : JBM Vol 4, No 3 (2012): JURNAL BIOMEDIK : JBM Suplemen
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/jbm.4.3.2012.1202

Abstract

Abstract: Osteoarthritis is a degenerative disease and manifests itself as the most common type of arthritis affecting older people. This disease can cause significant pain and functional disability in the affected individuals. The therapy for osteoarthritis is easily available but the results are without certainty. Symptomatically therapeutic agents such as acetaminophen and NSAIDs are only beneficial for relieving the symptoms. Unfortunately, these agents can trigger severe side effects in some patients or may be contraindicated. Glucosamine has been evaluated in several studies as an agent to relieve pain, increase functional activity, and slow the progression of osteoarthritis, especially in the knees. Studies have reported some improvement in pain and disability in osteoarthritic patients related to the use of glucosamine. Based on the current evidence, a combination of glucosamine sulfate and chondroitin sulfate shows the greatest potential as a therapeutic intervention for patients who might risk side effects from other oral medications currently in vogue. However, research is still needed to explore the benefits of glucosamine or its combination forms in order to ensure safety for long-term use. Keywords: osteoarthritis, glucosamine, pain.     Abstrak: Osteoartritis merupakan penyakit degeneratif yang menyebabkan rasa nyeri dan cacat fungsional pada individu yang terkena dan umumnya mempengaruhi lanjut usia. Kemajuan dalam pengobatan osteoartritis relatif tersedia tetapi belum secara pasti untuk mengobatinya. Terapi andalan seperti asetaminofen dan obat NSAID hanya untuk mengobati gejala, tetapi dapat memicu efek samping yang parah pada pasien atau mungkin merupakan kontraindikasi. Beberapa studi mengemukakan glukosamin sebagai agen untuk menghilangkan rasa nyeri, meningkatkan aktivitas fungsional, dan memperlambat progresivitas osteoarthritis, terutama pada lutut. Juga telah dilaporkan perbaikan dalam rasa nyeri dan kecacatan yang terkait dengan penggunaan glukosamin baik sebagai agen tunggal maupun bentuk kombinasi glukosamin sulfat dengan kondroitin sulfat. Penggunaan produk kombinasi tersebut tampaknya memiliki potensi besar untuk pasien yang berisiko akibat efek samping terapi oral. Masih dibutuhkan penelitian lanjut mengenai manfaat dan kemanan glukosamin terutama pada pemakaian jangka panjang. Kata kunci: osteoartritis, glukosamin, nyeri.
Proyek Pembangunan Jalan Masuk Di Pantai Koala Martika, Aprilia; Utami, Pratiwi; Helen, Princes; Trimanda Yolanda, Silvi; Afdal Samsuddin, M.
BINER : Jurnal Ilmu Komputer, Teknik dan Multimedia Vol. 2 No. 4 (2024): BINER : Jurnal Ilmu Komputer, Teknik dan Multimedia
Publisher : CV. Shofanah Media Berkah

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The construction of the entrance road at Koala Beach aims to increase accessibility and support the development of natural tourism potential in this coastal area. This project involves planning, design and construction of roads taking into account technical, environmental and social aspects. This study discusses the stages of development which include location analysis, material selection, and the application of environmentally friendly construction technology. In addition, special attention is paid to environmental impacts, including mitigation efforts for coastal erosion and protection of coastal ecosystems. This research also evaluates the technical and topographic aspects required for constructing an access road. By considering many factors the optimal location for the construction of the driveway was identified. This study uses quantitative descriptive methods with secondary data collection and financial analysis involving parameters such as Net Present Value (NPV), Internal Rate of Return (IRR), Benefit Cost Ratio (BCR), and Payback Period (PP). The analysis results show that this project is financially feasible, with an NPV of IDR 1,277,944,618.73 (10% discount) and IDR 1,426,570,044.87 (15% discount), IRR of 12%, BCR of 2.04, and Payback Period 2.22 years. With a well-structured entrance, it is hoped that it can increase local tourism, open up new economic opportunities for the surrounding community, and strengthen the sustainability of natural resource management on Koala Beach. This research also offers recommendations regarding sustainability-based infrastructure planning for similar projects in other coastal areas.
Analisis Respons Publik di Media Sosial Terhadap Proses Legislasi RUU TNI Dalam Kerangka Demokrasi Deliberatif Utami, Pratiwi
Communicology: Jurnal Ilmu Komunikasi Vol. 13 No. 1 (2025): Communicology: Jurnal Ilmu Komunikasi, Volume 13 No. 1 Juli 2025
Publisher : Sarjana Terapan Prodi Humas dan Komunikasi Digital Fakultas Ilmu Sosial Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/COMM.034.09

Abstract

This article analyzes public responses to the legislative process of the revision of the Indonesian National Armed Forces Law (RUU TNI), highlighting a gap between public rejection and the political decision to proceed with its ratification. Using a qualitative-critical approach and the framework of deliberative democracy, the study draws on secondary data from Social Network Analysis (SNA) by Drone Emprit. Findings show that 81% of public sentiment in digital spaces was negative, driven by concerns over the return of the military’s dual function and the lack of public participation in the legislative process. This reflects a legitimacy crisis, as deliberative democracy emphasizes that legal validity must be accompanied by public engagement and acceptance. The article contributes to the discourse on weak policy communication and the urgent need to open deliberative spaces in public policymaking. However, the study relies on digital data, which may not fully capture the broader spectrum of societal aspirations. Future research should adopt a communication ethnography approach and conduct quantitative studies on public perceptions across regions to gather more geographically and demographically representative data.                                                                                                       ABSTRAK Artikel ini menganalisis respons publik terhadap proses legislasi Revisi Undang-Undang Tentara Nasional Indonesia (RUU TNI), yang menunjukkan ketimpangan antara penolakan publik dan keputusan politik untuk tetap mengesahkannya. Menggunakan pendekatan kualitatif-kritis dan kerangka demokrasi deliberatif, studi ini memanfaatkan data sekunder dari Social Network Analysis (SNA) oleh Drone Emprit. Temuan menunjukkan bahwa 81% sentimen publik di ruang digital bersifat negatif, dipicu oleh kekhawatiran terhadap kembalinya dwifungsi TNI dan minimnya partisipasi publik dalam proses legislasi. Kondisi ini merefleksikan krisis legitimasi, karena dalam demokrasi deliberatif, legalitas formal tidak cukup tanpa keterlibatan dan penerimaan masyarakat. Artikel ini berkontribusi pada diskursus tentang lemahnya komunikasi kebijakan dan urgensi membuka ruang deliberatif dalam legislasi publik. Keterbatasan kajian terletak pada basis data digital yang belum mencerminkan keseluruhan spektrum aspirasi masyarakat. Studi lanjutan disarankan menggunakan pendekatan etnografi komunikasi atau kajian kuantitatif terhadap persepsi masyarakat lintas wilayah untuk memperoleh data yang lebih representatif secara geografis dan demografis.    
Service Quality and E-Health Literacy Impact on Elderly Patient Loyalty at Hospital X Utami, Pratiwi; Ardi, Ardi; Waisan, Dewi Sri Surya; Sumaryo, Richard Andre
Indonesian Interdisciplinary Journal of Sharia Economics (IIJSE) Vol 8 No 3 (2025): Sharia Economics
Publisher : Sharia Economics Department Universitas KH. Abdul Chalim, Mojokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31538/iijse.v8i3.7551

Abstract

The aging population increasingly relies on healthcare services, demanding hospitals to identify factors influencing elderly patients' revisit intentions. However, limited studies integrate service quality and digital literacy factors. Thus, this research addresses how service quality dimensions and e-health literacy affect elderly patients' revisit intentions mediated by customer perceived value (CPV) and customer satisfaction (CS). The objectives were to examine the direct and indirect effects of service quality and e-health literacy on revisit intention, with CPV and CS as mediators. A cross-sectional survey employing standardized questionnaires was conducted among approximately 300 elderly outpatients at Hospital X. Partial Least Squares Structural Equation Modeling (PLS-SEM) was utilized to analyze the data. Results demonstrated significant positive effects of service quality on both CPV and CS, while e-health literacy positively influenced CPV. CPV significantly predicted CS, and CS was the strongest predictor of revisit intention, fully mediating the effects of service quality and CPV on revisit intention. The key significant path coefficients were service quality to satisfaction (β ≈ .50, p<.01), CPV to satisfaction (β ≈ .60, p<.01), and satisfaction to revisit intention (β ≈ .52, p<.001). These findings highlight the crucial role of enhancing service quality and e-health literacy among elderly patients to improve their perceived value and satisfaction, ultimately increasing revisit intentions. The implications suggest healthcare management should prioritize high-quality services and digital health literacy programs for elderly patients.