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Hastuti Herman
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Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Energy Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences

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Efek Pemberian Induksi Etanol Absolut terhadap Perubahan Histologi Jaringan Gaster pada Tikus Model Gastritis Hastuti Herman
Majalah Kedokteran Andalas Vol 45, No 3 (2022): Online July 2022
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v45.i3.p367-373.2022

Abstract

Tujuan: Penelitian ini bertujuan untuk menilai pengaruh pemberian etanol absolut pada perubahan histologi dinding gaster. Metode: Tikus (Rattus norvegicus) jantan dengan berat badan 220g sebanyak delapan ekor dibagi kedalam dua kelompok (n = 4) yaitu kelompok kontrol tanpa pemberian etanol absolut dan kelompok gastritis yang diberi etanol absolut 1 ml. Setelah proses pembedahan dinding gaster dievaluasi secara makroskopik dan mikroskopik. Hasil: Induksi etanol absolut menyebabkan lesi hemoragik pada mukosa luminal gaster secara makroskopik. Sedangkan pengamatan histologi menunjukkan adanya tanda ulserasi, deskuamasi epitel, hemoragik akut pada mukosa, dan edema sub-mukosa, sedangkan muskularis tidak ditemukan kelainan pada lapisan muskularis dan serosa.  Kesimpulan: Etanol absolut yang diberikan pada tikus model gastritis menunjukkan lesi makroskopik berupa hemoragik mukosa luminal dan perubahan histologis berupa ulserasi, deskuamasi epitel, hemoragik akut, dan edema sub-mukosa, sedangkan lapisan muskularis dan serosa tampak normal.
Histopathology Of Organ Tissues In Dengue Fever Patients: A Narrative Review Herman, Hastuti; Sunarto , Sunarto
Jurnal Indonesia Sosial Sains Vol. 6 No. 7 (2025): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v6i7.1815

Abstract

Dengue hemorrhagic fever is one of the tropical diseases that is still a global public health problem, this is closely related to the environmental conditions that support the life cycle of the Aedes species mosquito, which is the vector of its spread. Laboratory testing to support diagnosis is generally by examining viral or serological components. The technique is limited to the acute phase, so the role of histopathological aspects that explain changes in tissue structure in organs is significant. The histopathology reports of dengue hemorrhagic fever patients in this literature review will be summarized so that they can be used as a reference source for medical laboratory technology students, strengthening understanding of the tissue pathology of dengue virus infection. A total of ±126 million academic articles, reduced to the 50 papers most relevant to the research question. There are 7 articles that meet the criteria. Post-infectious organ tissue in dengue hemorrhagic fever patients, showing various conditions such as necrosis, edema, hemorrhage, vascular congestion in various organs; infiltration of inflammatory cells; viral replication characterized by the expression of dengue virus antigens in various cells; as well as the expression of chemokines and cytokines.
Histopathology Of Organ Tissues In Dengue Fever Patients: A Narrative Review Herman, Hastuti; Sunarto , Sunarto; Fitriana, Fitriana; Alam, Nur; Tupanwael, Fenti A.
Jurnal Indonesia Sosial Sains Vol. 6 No. 7 (2025): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v6i7.1815

Abstract

Dengue hemorrhagic fever is one of the tropical diseases that is still a global public health problem, this is closely related to the environmental conditions that support the life cycle of the Aedes species mosquito, which is the vector of its spread. Laboratory testing to support diagnosis is generally by examining viral or serological components. The technique is limited to the acute phase, so the role of histopathological aspects that explain changes in tissue structure in organs is significant. The histopathology reports of dengue hemorrhagic fever patients in this literature review will be summarized so that they can be used as a reference source for medical laboratory technology students, strengthening understanding of the tissue pathology of dengue virus infection. A total of ±126 million academic articles, reduced to the 50 papers most relevant to the research question. There are 7 articles that meet the criteria. Post-infectious organ tissue in dengue hemorrhagic fever patients, showing various conditions such as necrosis, edema, hemorrhage, vascular congestion in various organs; infiltration of inflammatory cells; viral replication characterized by the expression of dengue virus antigens in various cells; as well as the expression of chemokines and cytokines.
Co-Authors Fitriana Fitriana Nur Alam Sunarto , Sunarto Tupanwael, Fenti A.