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All Journal Jurnal technoscientia JURNAL TEKNOLOGI TECHNOSCIENTIA Indonesian Journal of Pharmacology and Therapy
Samekto Wibowo
Lab/Bag.I.Penyakit Saraf FK UGM/RS Dr. Sardjito Yogyakarta
Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Earth & Planetary Sciences Engineering Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology

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APLIKASI STREAMING MULTIMEDIA PADA M-DOCTOR DENGAN SELULAR WCDMA Santoso, Gatot; Sutanta, Edhy; Wibowo, Samekto
JURNAL TEKNOLOGI TECHNOSCIENTIA Technoscientia Vol 3 No 1 Agustus 2010
Publisher : Lembaga Penelitian & Pengabdian Kepada Masyarakat (LPPM), IST AKPRIND Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (222.34 KB) | DOI: 10.34151/technoscientia.v3i1.432

Abstract

Information technology and ielecommunications to the Internet becomes the main priority in the development of world progress. These developments provide new break-through in health care services mobile using mobile IT devices or socalled mobile doctor (m-doctor). M-doctor has some excess capacity for health care services that can be accessed anytime, anywhere, by anyone. The problems that still esist on still on m-doctor is that the lack of hardware and platforms that required by the system design and ease of access. One also needs a special study of each section dealing with the existing m-doctor in order to get comfortable for the user. The aim of this study is to address the issue by using streaming multimedia as content that can offer a more clear and specific infor-mation. Streaming multimedia services m-doctor require internet connection and good access, and also requires capable hardware to enjoy the overall bias with good services by using phones that support streaming multimedia mobile facilities. Expected results of this study is a software-based content cellular WCDMA, and the main target is to design m-doctor with streaming multimedia services.
APLIKASI STREAMING MULTIMEDIA PADA M-DOCTOR DENGAN SELULAR WCDMA Santoso, Gatot; Sutanta, Edhy; Wibowo, Samekto
JURNAL TEKNOLOGI TECHNOSCIENTIA Technoscientia Vol 3 No 1 Agustus 2010
Publisher : Lembaga Penelitian & Pengabdian Kepada Masyarakat (LPPM), IST AKPRIND Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34151/technoscientia.v3i1.432

Abstract

Information technology and ielecommunications to the Internet becomes the main priority in the development of world progress. These developments provide new break-through in health care services mobile using mobile IT devices or socalled mobile doctor (m-doctor). M-doctor has some excess capacity for health care services that can be accessed anytime, anywhere, by anyone. The problems that still esist on still on m-doctor is that the lack of hardware and platforms that required by the system design and ease of access. One also needs a special study of each section dealing with the existing m-doctor in order to get comfortable for the user. The aim of this study is to address the issue by using streaming multimedia as content that can offer a more clear and specific infor-mation. Streaming multimedia services m-doctor require internet connection and good access, and also requires capable hardware to enjoy the overall bias with good services by using phones that support streaming multimedia mobile facilities. Expected results of this study is a software-based content cellular WCDMA, and the main target is to design m-doctor with streaming multimedia services.
Potential neurological applications of Centella asiatica: a brief review Gofir, Abdul; Wibowo, Samekto; Hakimi, Mohammad
Indonesian Journal of Pharmacology and Therapy Vol 2 No 3 (2021)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.1693

Abstract

Centella asiatica (C. asiatica) or gotu kola has been used traditionally in many Asian countries as herbal medicines for many conditions, such as headache, asthma and memory enhancement. Centella asiatica has been also widely investigated for its neuroprotective effects in animal disease model including epilepsy, Alzheimer’s and Parkinson’s diseases. A brief review of neurological effects studies of C. asiatica in animal model was reported. Eligible studies published through December 2020 from PubMed and EMBASE journal data base were collected. Any keywords related to C. asiatica or gota kola AND neurological conditions were used. The results showed that several experimental studies concerning the neuroprotective properties of C. asiatica have been reported. Phytochemical studies reported that C. asiatica contained many bioactive compounds in which triterpenoids are the most identified. Furthermore, the triterpenoids have proven to have neuroprotective effect due to their effects of anti-inflammatory, antioxidant, improvement of mitochondrial dysfunctions, and increased brain-derived neurotrophic factors. Further studies are needed to investigate the neuroprotective mechanisms of C. asiatica. In conclusion, C. asiatica might have potential as an alternative medicine for neurological conditions, such as stroke, epilepsy, Alzheimer’s and Parkinson’s disease.
The effect of Centella asiatica L. Urban. and Curcuma longa L. extracts combination in improving memory performance in stroke model rats and its acute toxicity Gofir, Abdul; Ar Rochmah, Mawaddah; Wibowo, Samekto; Hakimi, Mohammad; Mustofa
Indonesian Journal of Pharmacology and Therapy Vol 2 No 2 (2021)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.1765

Abstract

Post-stroke cognitive impairment involves memory, visuoconstructional, and spatial dysfunctions. Centella asiatica L. Urban. and Curcuma longa L. are both well-known herbs in South and South-East Asia countries that are believed to possess neuroprotective properties as memory enhancers. This study aimed to investigate the effects of C. asiatica L. Urban. and C. longa L. extracts combination in improving memory performance in stroke model rats and its acute toxicity. Twenty-five Wistar rats underwent transient bilateral common carotid artery occlusion. Y-maze pre-test was performed 24 h after the occlusion. The rats were then divided into five groups i.e. Group 1 received NaCMC dilution, Group 2 received donepezil 0. 7 mg/kg BW/day, and Groups 3, 4, and 5 received the extracts combination with dose of 59; 118; and 236 mg/kg BW/day, respectively. Y-maze post-test was performed 24 h after the last dose had been given. Spontaneous alternation behavior was used as the indicator of working memory measurement. The fixed-dose method according to OECD Guideline was used to estimate the LD50 in acute toxicity testing on Wistar rats. There was a significant difference in the delta spontaneous alternation percentage among groups tested (p<0. 05). Group 1 had significant difference with any other group (compared to Groups 2 to 5; p<0.05). No significant difference could be found between groups of the extracts combination and donepezil group suggesting that the effect is not more inferior nor dose-dependent in improving memory performance. The extracts combination at a single dose of 2000 mg/kg BW did not show related signs of toxicity or mortality in any of the rats during the 14-day observation period. In conclusion, the C. asiatica L. Urban. and C. longa L. extracts combination can improve performance of memory on stroke model animal. According to Globally Harmonized Classification System, the extracts combination can be classified as Category 5/unclassified.
Co-Authors Abdul Gofir Edhy Sutanta (Jurusan Teknik Informatika IST AKPRIND Yogyakarta) Gatot Santoso Mawaddah Ar-Rochmah Mohammad Hakimi Mustofa Mustofa