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All Journal Jurnal Respirasi (JR)

Isnu Pradjoko

Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Hospital, Surabaya, Indonesia.

Author-ID : 4146912

Health Professions Medicine & Pharmacology Public Health

Published : 5 Documents Claim Missing Document

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Articles

Aspirasi Jarum Pentul yang Tertanam 10 Hari di Bronkus Kanan Seorang Remaja: [Aspiration of Implanted Pin in the Right Bronchus of a Teenager for More than a Week: A Case Report] Isnu Pradjoko; Irmi Syafa’ah; Aries Subianto
Jurnal Respirasi Vol. 3 No. 2 (2017): Mei 2017
Publisher : Faculty of Medicine Universitas Airlangga

Background: Foreign bodies can come from outside the body (exogenous) and in the body (endogenous). Foreign bodies can cause total obstruction resulting in atelectasis or partial obstruction with emphysema. Case: A 14-year-old girl with a cough with phlegm mixed with blood spots one day before admission. Patients swallowed needle 10 days ago while wearing jilbab while joking at school. Chest X-rays appear density of a metal with a long straight form of about 3.5 cm projected in the lower right hemitorac. Discussion: Performed Fiber Optic Bronchoscopy (FOB) with diagnostic and therapeutic indications for picking up foreign objects. In patients there is minimal bleeding post extraction pentul needle. Bleeding can be overcome by administering a cold sterile NaCl solution to the airway. Thoracotomy is not performed on the patient because the needle can be taken using FOB. Conclusion: Foreign bodies of the airways can be harmful. The needle extraction using FOB can rule out the need for thoracotomy in patients.

Sindrom Hepatopulmoner: [Hepatopulmonary Syndrome] Kowiy Akbar; Isnu Pradjoko
Jurnal Respirasi Vol. 1 No. 2 (2015): Mei 2015
Publisher : Faculty of Medicine Universitas Airlangga

Hepatopulmonary syndrome (HPS) is an important complication of liver disease on pulmonary organ; characterized by the triad of liver disease, pulmonary vascular dilatation, and oxygenation defect. Clinical signs and symptoms include dyspnea, platypnea, orthodeoxia, cyanosis, and clubbing finger. The underlying patophysiology involves abnormal vasodilation and angiogenesis in the pulmonary vascular bed, which leads to ventilation-perfusion mismatch, diffusion limitation to oxygen exchange, and arteriovenous shunting. This disorder is thought to be linked to liver cell injury, which stimulates release of endothelin-1 and results in increased expression of endothelin receptors on pulmonary endothelial cells, leading to upregulation of endothelial-nitric-oxide-synthase (eNOS) and subsequent increased production of nitric oxide (NO), ultimately causing vasodilation. Laboratory studies to establish diagnosis includes blood gas analysis and echocardiography, supported by radiology and pulmonary vascular cathetherization. Despite accumulated knowledge about the pathogenesis of HPS, currently there is still no established medical therapy, and liver transplantation remains the definitive treatment for this syndrome. Supportive therapy consists oflong term oxygen administration to prevent desaturation and alleviate dyspnea.

Nilai Diagnostik Adenosine Deaminase (ADA) Cairan Pleura pada Penderita Efusi Pleura Tuberkulosi: [The Value of Adenosine Deaminase of Pleural Fluid in Tuberculosis Patient] Rizki Nur Amalia; Isnu Pradjoko
Jurnal Respirasi Vol. 2 No. 2 (2016): Mei 2016
Publisher : Faculty of Medicine Universitas Airlangga

Background: Tuberculosis pleural effusion is the most common extrapulmonary TB after lymphadenitis TB. Limited diagnostic methods make TB pleural effusion hard to diagnose. Adenosine deaminase ADA is an enzyme in purin catabolism process which catalyze adenosine into inosine and deoksiadenosine into deoksiinosin. This process is important in lymphoid cell differentiation. ADA is elevated in TB pleural effusion. Method: This study was a cross sectional analytic observational. Statistic analysis was using two independent samples T test. ROC curve was used to determine cut off value of ADA. Kappa test was used to determined the level of agreement of ADA cut off value. Results: Forty eight samples were included in this study, 18 samples with TB pleural effusion and 30 samples with non TB pleural effusion. There was significant difference between pleural fluid ADA in TB and non TB. Positivity of AFB sputum and MTB culture did not show any significant differences. Cut off ADA value for TB pleural effusion diagnosis was 39,19 with sensitivity 88,9% and spesificity 90%. Conclusion: Examination of ADA level in pleural fluid is a usefull tool to diagnose TB pleural effusion.

Manajemen Ekstravasasi Kemoterapi: [Extravasasion Chemoteraphy Management] Nur Nubli Julian Parade; Isnu Pradjoko
Jurnal Respirasi Vol. 5 No. 1 (2019): Januari 2019
Publisher : Faculty of Medicine Universitas Airlangga

Extravasation is a problem for patient receiving chemotherapy. This will cause pain, ulcer, necrosis and might be a permanent disability. Extravasation is a leakage of a fluid or medicine to the surrounding subcutaneous tissue of the vein or vascular, that may cause skin or tissue necrotic. There was a wide span of incidence data of extravasation on the literature, between 0,01% and 11% reported from child to adult. Management of extravasation was based on proper maintenance of the intravenous (IV) line and application of cold or warm compresses, plus the use of antidotes when available. Antidotes for extravasation that have been shown to be useful are sodium thiosulfate for nitrogen mustard, dimethylsulfoxide for anthracyclines and mitomycin, and hyaluronidase for the vinca alkaloids. New treatments include dexrazoxane, sargramostim, and hyperbaric oxygen for doxorubicin extravasations. In order to improve patient service quality and reduce morbidity, every medical staff handle cancer patient receiving chemotherapy should have sufficient knowledge about how to manage extravasation event.

Nutrisi pada Penderita Kanker Paru : [Nutrition Management in Lung Cancer Patients] Risnawati Risnawati; Isnu Pradjoko; Farah Fatma Wati
Jurnal Respirasi Vol. 5 No. 3 (2019): September 2019
Publisher : Faculty of Medicine Universitas Airlangga

World Health Organization data shows that lung cancer is the leading cause of death in the group of deaths due to malignancy. Weight loss is common in lung cancer. Known side effects of chemotherapy and those that affect nutritional status include anorexia, nausea, vomiting, satiety and mucositis. In total 40-60% of lung cancer patients experience unintentional weight loss. Weight loss and reduced nutritional status have been identified as negative prognostic variables for patients. Nutritional disorders during chemotherapy if left untreated can cause interference and delay treatment. Therefore there is a need for nutritional management in patients with lung cancer so that treatment runs smoothly and supports patient health.

Co-Authors Aries Subianto Farah Fatma Wati Kowiy Akbar Nur Nubli Julian Parade Risnawati Risnawati Rizki Nur Amalia Syafa’ah, Irmi

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