Winariani Koesoemoprodjo
Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine, Universitas Airlangga/Dr. Soetomo General Hospital, Surabaya, Indonesia.

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Diagnosis and Outcome of Tuberculosis of Knee Joint (Gonitis Tuberculosis) with Pulmonary Tuberculosis after Completing Anti-Tuberculosis Therapy: A Case Report Anita Nur Charisma; Winariani Koesoemoprodjo
Jurnal Respirasi Vol. 7 No. 1 (2021): January 2021
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (543.426 KB) | DOI: 10.20473/jr.v7-I.1.2021.19-26

Abstract

Background: Tuberculosis (TB) in extra-pulmonary organs, such as bone and joint TB, has an incidence rate of 19% of the cases and represents 11-15% of all extra-pulmonary TB. The predilection of bones and joints is the most common predilection with more than 10% of the cases. Gonitis TB is a monoarthritis, chronic progressive, and intermittent disease. Hematogenous spreads through synovial or subchondral or as a focus in the juxta-articular bone. The spread can also occur indirectly from osseous lesions of the epiphyseal bone in adults or metaphysis in children, which causes erosion in the joint space and becomes arthritis.Case: A 19-year-old female with a chief complaint of swelling in the right knee joint accompanied by pain and difficulty in the legs to move and straighten the body. Another complaint was cough with whitish sputum, fever and night sweating, decreased appetite, and loss of body weight. Radiological chest X-ray showed fibro-infiltrates in both hemithoraces and radiological of the right genu, impression like joint effusion and mass density opacity in the popliteal, and suspicious abscess in the soft tissue. GeneXpert MTB/RIF examination of genu tissue and sputum: medium  Mycobacterium tuberculosis (M.Tb) was detected, rifampicin sensitive. Histopathology from the open biopsy showed the tissue consisted of epitheloid-shaped histiocyte cells forming granulomas. Ziehl Neelsen staining of the tissue obtained acid-fast bacillus (AFB).Conclussion: Gonitis TB is a hematogenous spread of M.Tb from infection with a deep primary focus on the joint that is chronic progressive and generally affects one joint. The management can be done by administering anti-tuberculosis and clinical monitoring.
Seorang Laki-laki Usia 16 Tahun yang Mengalami Drowning dan Pneumotoraks Paska Pemasangan Ventilator Mekanik: [Pneumothorax in a Ventilated Young Man after Drowning: A Case Report] Ira Nurrasyidah; Winariani Koesoemoprodjo
Jurnal Respirasi Vol. 1 No. 1 (2015): Januari 2015
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.775 KB) | DOI: 10.20473/jr.v1-I.1.2015.15-21

Abstract

Background; Drowning is defined as respiratory impairment due to submersion/immersion in liquid. The liquid/air interface at the entrance of the airway prevents the victim from breathing air. According to the World Health Organization (WHO), 0.7% of all deaths worldwide - or more than 500,000 deaths each year - are due to unintentional drowning. Drowning is the second leading cause of unnatural death after road traffic injuries. Most of these deaths occur in countries with low or middle per capita income. Case; A16-years-old man rescued after drowning in the mud puddle for 15 minutes. He was unconscious, cyanosis, dyspnea and cough with blood and mud. After receiving oxygen in the nearest hospital he got conscious but still dyspnea. He came to our hospital and after undergone several examination we concluded that he had lung edema, ARDS and pneumonia aspiration. Patient immediately intubated and got mechanical ventilation. Five days later patient encounter pneumothorax on the right hemithorax, maybe due to barotrauma and we perfomed a chet tube insertion for three days. Patient had a good progression, there was no deficit neurologic and injury in the other organ. On follow up five months after patient hospitalized revealed normal condition on chest x ray.
Peranan Ultrasonografi Toraks dalam Menegakkan Diagnosis Beberapa Kelainan pada Paru: [The Role of Ultrasound in Diagnosing Pulmonary Diseases] Erwin Winaya; Winariani Koesoemoprodjo
Jurnal Respirasi Vol. 1 No. 1 (2015): Januari 2015
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (733.611 KB) | DOI: 10.20473/jr.v1-I.1.2015.29-39

Abstract

Ultrasound is useful in the diagnosis of cases in the field of lung disease, such as pleural effusion, pneumothorax, consolidation, atelectasis, pulmonary edema, and others. The advantages of thoracic ultrasound is a low cost, radiation is small, easy to carry, short examination time and has a dynamic aspect that can be seen at the time of examination. Thoracic ultrasound is an inexpensive tool and can be used to assist in intervention, especially in cases of peripheral lung, pleura and chest wall diseases, such as thoracocentesis, chest tube installation and aspiration lung abscess. Ultrasound can also replace aspiration and biopsy with CT-scan guidance in cases involving the pleura, chest wall, and lung tumors that invade the pleura and chest wall. With the ultrasound portable and compact form, in the future is possible if the ultrasound will be a routine part of the examination as well as a stethoscope. However, ultrasound also has limitations which in patients with subcutaneous emphysema, peripheral edema and obesity, lung ultrasound is hard to do. Ultrasound examination is also highly dependent on the experience and ability of the ultrasound operator.
Seorang Perempuan Terinfeksi Tuberkulosis dengan Manifestasi Sindroma Distres Napas Akut (ARDS): [Acute Respiratory Distress Syndrome as a Manifestation of Tuberculosis in a Woman: A Case Report] Putu Dyah Widyaningsih; Winariani Koesoemoprodjo
Jurnal Respirasi Vol. 2 No. 1 (2016): Januari 2016
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (610.108 KB) | DOI: 10.20473/jr.v2-I.1.2016.6-13

Abstract

Tuberculosis remains a global issue throughout the world. Indonesia currently ranks 4th worldwide. Although rarely reported, TB could be one of the etiologies of Acute Respiratory Distress Syndrome. A 27-year-old woman was admitted with shortness of breath 12 days post partum with cough, loss of appetite and malaise. Chest examination revealed increased fremitus on both lungs and rhonchi on 2/3 lower part of the lung. There was edema on both of the leg. Radiologic finding suggested reticulogranuler pattern on both lungs. Laboratory showed granulocytosis, anemia and hypoalbumin with severe hypoxemia and PaO2/FIO2 ratio of 107. Transthoracic Echocardiography showed PCWP of 12,25 mmHg. Patient was diagnosed with moderate Acute Respiratory Distress Syndrome but there was no improvement after definitive antibiotic therapy. Based on clinical judgment, patients suspected of having tuberculosis and given anti tuberculosis drugs with a regimen of rifampicin, isoniazid, ethambutol, pyrazinamide, and streptomycin along with methylprednisolone and supportive therapy. Microscopic examination of acid-fast bacilli sputum shows positive result one day after the treatment started. Patient was showing significant improvement and declare cured after completed 6 month of therapy. Conclusions: Although the incidence is rare, tuberculosis can act as the primary cause of ARDS. Early diagnosis of tuberculosis is the key point of this case. Initial therapy along with good supportive therapy should be given to ARDS patient while the underlying cause is treated.
Seorang Penderita Siliko Tuberkulosis dengan Penyulit Pneumotoraks: [Pneumothorax in a Silico-Tuberculosis Patient: A Case Report] Winariani Koesoemoprodjo; Vinodini Merinda
Jurnal Respirasi Vol. 2 No. 3 (2016): September 2016
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (570.309 KB) | DOI: 10.20473/jr.v2-I.3.2016.76-81

Abstract

Background: Silicosis is a lung disease caused by the work because of respirable crystalline silica. Often occurs in workers mining gold, iron, tin, granite, sandstone, slate, foundries, cement, ceramics and glass. The risk of silicosis develop into lung tuberculosis (TB) is higher than patients without silicosis. Another complication of silicosis is secondary spontaneous pneumothorax. Case : A man, 45 years old with a history of work as a bricklayer for 5 years with complaints shortness of breath since three days before admitted to the hospital, chest pain in the right hemithorax, and had chronic cough. Patients is on ATD therapy. From radiographic there is collapse lung, it was shown collapse line on the right hemithorax, and fibroinfiltrat with multiple cavities on both hemithorax. Patients then got chest tube insertion and evaluation for 3 weeks, but the lung has not expanded. From thoracoscopy, there is fibrotic band on the pleural space with conclution right trapped lung. From forcep biopsy on visceral pleura showed a widened alveolar epithelial layer coated with a pile of inflammatory lymphocytes and dust pigments. From broncoscopy, there is chronic lung inflamation. Spectrophotometric analysis from BAL specimens results showed a silica content of 4.25 ppm SiO2 from left BAL an 14.34 ppm SiO2 on the right BAL. Furthurmore, this patient got pleurodesis using betadine agent and continue the ATD. Evaluation the lung is fully expanded. Conclusion : This case illustrates the secondary spontaneous pneumothorax as a complication of silicotuberkulosis. No drug has proven effective for silicosis. Treatment is aimed to the disease complications that occur, in this case is secondary spontaneous pneumothorax and lung TB. Prevention at workplaces that have a risk of silicosis is very important.
Seorang Wanita dengan Pneumokoniosis yang Mengalami Komplikasi Trapped Lung dan Dilakukan Dekortikasi: [Decortication of Trapped Lung in Pneumoconiosis Patient: A Case Report] Tutik Kusmiati; Winariani Koesoemoprodjo; Novita Maulidiyah
Jurnal Respirasi Vol. 3 No. 3 (2017): September 2017
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1076.4 KB) | DOI: 10.20473/jr.v3-I.3.2017.74-80

Abstract

Background: Pneumoconiosis is an occupational lung disease caused by dust inhalation which deposit in lung parenchym and cause lung fibrosis. Trapped lung is impairment of compliance because of pleural inflammation. Case: We presented a diagnostic problem case of a woman, 37 years old who worked at coffee factory for 20 years as a coffee powder packer. Patient came in previous hospital with continous dispnea not relieved by rest or medication. She had been diagnosed with pneumothorax and already treated with chest tube for 2 weeks but there was no improvement. Patient was reffered to Dr. Soetomo hospital and treated with continous suction and chest physiotherapy for 2 months but there was no improvement. Patient then underwent thoracoscopy to find the cause of persistent collapsed lung. Thoracoscopy showed blackish leucoplaque pleural biopsy was done histopathological result showed pneumoconiosis. CT Scan showed fluidopneumothorax and severe lung restriction. The patient then underwent torachotomy and decortication which showed attachment of medial, inferior, and posterior lobe of left lung and organized pleural effusion. Post operation, the lung expanded completely and patient condition improved. Conclusion: Lung entrampment rarely become the complication of pneumoconiosis. Early diagnosis and appropriate treatment will avoid further complication.
Sidero-Siliko Tuberkulosis pada Penderita Efusi Pleura Masif Dekstra yang Awalnya Dicurigai Keganasan: [Malignant Suspicion of Massive Pleural Effusion in Sidero-Silico Tuberculosis Patient] Winariani Koesoemoprodjo; Hapsari Paramita Narendrani
Jurnal Respirasi Vol. 3 No. 3 (2017): September 2017
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (726.238 KB) | DOI: 10.20473/jr.v3-I.3.2017.81-88

Abstract

Background: Pneumoconiosis defined as the accumulation of dust in the lungs and causes tissue reactions to mineral materials from various industries that affect the respiratory system. Among the causes of pneumoconiosis are silica dust (silicosis) and iron dust (ciderosis). Pneumoconiosis provides a pathological reaction in lung tissue due to inhaled deposition of mineral particulate dust or persistent fiber material. The risk of infection with tuberculosis is higher in patients with pneumoconiosis, especially silicosis. Most cases of pleural effusion are found in malignancies or infections such as tuberculosis but can also be a complication of pneumoconiosis. Case: A man, 55 years old, reported with a 2-week congested complaint that was getting worse, with a cough for almost 1 month. Patients with work history as iron lathers for 25 years with comorbid diabetes mellitus. From the results of our chest x-rays we get a picture of massive pleural effusion with a total evacuation of approximately 9 liters, whereas on the chest CT scan get a solid mass picture in the right lung field with multiple nodules in the liver. The results of bronkoalveolar rinses obtained silica and iron content, and obtained Mycobacterium tuberculosis culture in pleural fluid culture. Conclusion: Illustration of a case report of a 55-year-old man diagnosed as a sidero-silico-tuberculosis with a periodic picture of tuberculosis and pleural effusion in the right lung undergoing resolution with OAT treatment.
Pneumotoraks Bilateral dan Transaminitis Non Spesifik pada Silikosis: [Bilateral Pneumothorax and Transaminitis in Silicosis Patient: A Case Report] Sahrun Sahrun; Winariani Koesoemoprodjo; Ariani Permatasari
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (529.871 KB) | DOI: 10.20473/jr.v4-I.3.2018.76-85

Abstract

Background: Silicosis is a fibrosis in the lung caused by inhalation, retention, and reaction to crystalline silica. The prevalence rate is potentially increasing throughout the world. Cases of bilateral spontaneous pneumothorax and transaminitis due to complications of silicosis are very rare. In this case, the patient was presented with bilateral secondary spontaneous pneumothorax as well as in the development of the diagnosis of silicosis, liver dysfunction, and pneumonia. Case: A 36-year-old male was admited to hospital with shortness of breath, the patient was once stone artisans for 7 years, rarely using PPE. Bilateral pneumothorax was established based on the results of clinical and radiological examinations. HRCT showed that it supported silicosis, left fluidopneumothorax, and right pneumothorax. Bronchoscopy was not possible due to the incompatible conditions and subsequently the patient was examined for silica levels from both plueral fluid with significant pleural silica. Summary: Diagnosis of pulmonary silicosis was done by clinical, radiological, and silica analysis of bronchial rinses, but certain conditions of silica could be found from pleural fluid. Silicosis therapy with complications until recently is only symptomatic, definitive therapy has not been found. Silicosis complications can be from pneumothorax bilateral (rarely), tuberculosis, transaminitis, and pneumonia. Conclusion: Pulmonary silicosis can be found from pleural fluid when the amount is large enough, fibrosis and extensive lung damage occurred. Silicosis can have an impact on pneumothorax, liver disorders, pneumonia, tuberculosis, and respiratory problems.