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Novita Maulidiyah
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Hospital, Surabaya, Indonesia.
Health Professions Medicine & Pharmacology Public Health

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Biomarker Pernapasan pada Penyakit Paru: [Respiratory Biomarker in Pulmonary Diseases] Novita Maulidiyah; Muhammad Amin
Jurnal Respirasi Vol. 1 No. 2 (2015): Mei 2015
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (184.341 KB) | DOI: 10.20473/jr.v1-I.2.2015.67-71

Abstract

Breath analysis provides a convenient and simple alternative to traditional specimen testing in clinical laboratory diagnosis. As such, substantial research has been devoted to the analysis and identification of breath biomarkers. Development of new analytes enhances the desirability of breath analysis especially for patients who monitor daily biochemical parameters. Elucidating the physiologic significance of volatile substances in breath is essential for clinical use. This review describes the use of breath biomarkers in diagnosis of asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), lung cancer, as well as other pulmonary diseases. A number of breath biomarkers in lung pathophysiology will be described including nitric oxide (NO), carbon monoxide (CO), hydrogen peroxide (H2O2) and other hydrocarbons.
Seorang Wanita dengan Pneumokoniosis yang Mengalami Komplikasi Trapped Lung dan Dilakukan Dekortikasi: [Decortication of Trapped Lung in Pneumoconiosis Patient: A Case Report] Tutik Kusmiati; Winariani Koesoemoprodjo; Novita Maulidiyah
Jurnal Respirasi Vol. 3 No. 3 (2017): September 2017
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1076.4 KB) | DOI: 10.20473/jr.v3-I.3.2017.74-80

Abstract

Background: Pneumoconiosis is an occupational lung disease caused by dust inhalation which deposit in lung parenchym and cause lung fibrosis. Trapped lung is impairment of compliance because of pleural inflammation. Case: We presented a diagnostic problem case of a woman, 37 years old who worked at coffee factory for 20 years as a coffee powder packer. Patient came in previous hospital with continous dispnea not relieved by rest or medication. She had been diagnosed with pneumothorax and already treated with chest tube for 2 weeks but there was no improvement. Patient was reffered to Dr. Soetomo hospital and treated with continous suction and chest physiotherapy for 2 months but there was no improvement. Patient then underwent thoracoscopy to find the cause of persistent collapsed lung. Thoracoscopy showed blackish leucoplaque pleural biopsy was done histopathological result showed pneumoconiosis. CT Scan showed fluidopneumothorax and severe lung restriction. The patient then underwent torachotomy and decortication which showed attachment of medial, inferior, and posterior lobe of left lung and organized pleural effusion. Post operation, the lung expanded completely and patient condition improved. Conclusion: Lung entrampment rarely become the complication of pneumoconiosis. Early diagnosis and appropriate treatment will avoid further complication.
Co-Authors Kusmiati, Tutik Muhammad Amin Winariani Koesoemoprodjo