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RETINOBLASTOMA FAMILIAL IN A 3-YEAR-OLD GIRL Wini Mardewi, Kadek; Ariawati, Ketut
Medicina Vol 44 No 2 (2013): Mei 2013
Publisher : Medicina

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (174.201 KB)

Abstract

Retinoblastoma is the commonest intraocular tumor in childhood. About one thirds  of all cases are bilateral. It is recognized that bilateral and familial retinoblastoma are cause by germline mutation and are thus a heritable tumor. We reported a case, 3-year-old girl showing proptosis of the right eye since six months before admission. She had family history (his father) of retinoblastoma. Physical examination showed mass of the righ eye and leucorea of the left eye. Computed tomography scan showed  retinoblastoma extraoccular of the right eye and retinoblastoma intraoccular of the left eye without spread to the pinealis gland or Parsellar. Bone marrow aspration showed non hemopoitic cell (metastatic tumor). Patient was diagnosed with bilateral retinoblastoma familial grade V. Despite the management of this patient is chemotherapy and still on treatment chemotherapy continuous phase, the prognosis still worse. [MEDICINA 2013;44:128-134]
Low serum zinc and short stature in children Kadek Wini Mardewi; I Gusti Lanang Sidiartha; Eka Gunawijaya
Paediatrica Indonesiana Vol 56 No 3 (2016): May 2016
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.774 KB) | DOI: 10.14238/pi56.3.2016.171-5

Abstract

Background Short stature/stunting is common in developing countries, and has been used as an indicator of a nation’s general health condition. Short stature increases the risk of metabolic disease, disturbances in cognitive development, infection prevalence, physical as well as functional deficits, and even death. Nutritional factors that frequently cause stunting are low intake of energy, protein, or micronutrients such as iron, vitamin A, and zinc. The role of zinc supplementation in children with short stature has not been well defined. In addition, zinc supplementation should be evaluated in the setting of specific conditions and regions.Objective To assess the association between low serum zinc level and short stature in children.Methods This cross-sectional study was done in a primary health care center at Klungkung I, Klungkung District, from August to September 2013. Children with short and normal stature (as reference group) were enrolled and their serum zinc level was measured, Other risk factors were inquired by questionnaire. Association between low serum zinc level (<65 µg/dL) and short stature was analyzed by stepwise multivariable regression analysis; degree of association was presented as odds ratio (OR) and its corresponding confidence interval.Results The prevalence of low serum zinc level in our subjects was 71%. Low serum zinc level was significantly associated with short stature [adjusted OR 16.1; 95%CI 3.1 to 84.0; (P=0.001)]. In addition, the occurrence of low serum zinc was higher in the short stature group (88.5%) compared to the normal stature group (53.8%). We also found that low calorie intake was associated with short stature [adjusted OR 29.4; 95%CI 2.76 to 314.7; (P=0.001)].Conclusion Low serum zinc level appears to be associated with short stature. [Paediatr Indones. 2016;56:171-5.].
Description Of Nutritional Status And Differences In Stunting Incidence In Acute And Chronic Diseases In Childhood Inpatients At RSUD Klungkung Putu Wiliska Wilasitha; I Gede Catur Wira Natanagara; Kadek Wini Mardewi
Jurnal sosial dan sains Vol. 1 No. 12 (2021): Jurnal Sosial dan Sains
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1632.548 KB) | DOI: 10.59188/jurnalsosains.v1i12.286

Abstract

Latar belakang: Stunting adalah gangguan pertumbuhan linier yang ditunjukkan dengan nilai Z-score tinggi badan menurut usia (TB/U) kurang dari -2 standar deviasi (SD) berdasarkan standar World Health Organization (WHO). Stunting tetap menjadi salah satu masalah gizi utama di dunia dan mencerminkan efek kumulatif dari malnutrisi kronis selama 1.000 hari pertama kehidupan. Penelitian ini bertujuan mengetahui perbedaan kejadian stunting pada penyakit akut dan kronis pada pasien rawat inap di RSUD Klungkung. Metode: Desain penelitian analitik cross sectional. Pengumpulan data melalui rekam medik anak yang di rawat di RSUD Klungkung periode 1 Januari sampai 31 Desember 2018 dengan metode total sampling yang dipilih berdasarkan kriteria inklusi dan eksklusi yaitu anak usia 0-60 bulan. Data dianalisis univariat dan bivariat menggunakan uji chi square. Hasil: Selama periode penelitian tercatat 404 orang anak dirawat di RSUD Klungkung dengan 356 anak (88,1%) menderita penyakit akut dan 48 anak (11,9%) menderita penyakit kronis. Gambaran status gizi anak berdasarkan BB per TB/PB sebagai berikut: status gizi kurus (<-2SD) sebanyak 45 (11,1%) dan status gizi normal (≥ -2SD) sebanyak 359 (88,9%). Sedangkan gambaran TB/PB per Usia: status gizi pendek (<-2SD) sebanyak 45 (11,1%) dan status gizi normal (≥-2SD) sebanyak 359 (88,9%) anak. Hasil pengolahan data bivariat menunjukkan bahwa tidak terdapat perbedaan bermakna terhadap kejadian stunting pada penyakit akut dan kronis pasien rawat inap di RSUD Klungkung. (p=0,074) OR=2,051 (95% CI 0,919 – 4,577). Kesimpulan: Tidak terdapat perbedaan kejadian stunting pada penyakit akut dan kronis pasien rawat inap di RSUD Klungkung.