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Hospital Acquired Bacterial Infection in Burns Unit at Cipto Mangunkusumo Hospital, Jakarta PRATIWI SUDARMONO; VERONICA WIWING
Microbiology Indonesia Vol. 1 No. 1 (2007): April 2007
Publisher : Indonesian Society for microbiology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (54.867 KB) | DOI: 10.5454/mi.1.1.6

Abstract

Burn injury causes mechanical disruption to the skin, which allows environmental microbes to invade the deeper tissues. A prospective study of infections in burn patients has shown that the incidence of hospital acquired bacterial infection in burn wounds was high. In the Burns Unit, Cipto Mangunkusumo Hospital, Jakarta, 94 patients were hospitalized from January to July 2004. The objective of this study was to evaluate the hospital acquired infections in burn wounds. Using a cross sectional study, 49 patients were included. The specimens for bacterial investigation were obtained from clean eschar which has healthy tissue taken at day 1, day 5 and day 10. At the same time, bacterial investigations were conducted from the air and the water, as well as from the hand and nasal swabs of hospital personnel. The results show that Klebsiella pneumoniae is the most prominent bacterium found in the wounds, but it is also found in the air. Pseudomonas aeruginosa was the number two causative bacteria which caused a change of the bacterial infectivity on day 5 and 10. These bacteria were always found when we conducted bacterial investigations from the water resource of the burns unit. Methicillin Resistant Staphylococcus aureus is also found in the nasal swab of hospital personnel. Using the antibiogram pattern, there were similarities between bacteria found in the wounds and in bacteria found in the air and water. In conclusion, hospital acquired burn wound infection in Burns Unit, Cipto Mangunkusumo Hospital is as high as 62%. The surveillance data are very important for developing good clinical practice guidelines in burn injury treatment and management
In Vitro Susceptibility Of Tigecycline Among Acinetobacter Baumanii Clinical Isolates From a Hospital in Indonesia Veronica Wiwing; Cucunawangsih Cucunawangsih
Medicinus Vol 7, No 1 (2017): October 2017 - January 2018
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i1.1436

Abstract

Acinetobacter baumanii (A. baumanii) has arisen as the most important cause of nosocomial infection, typically in severely ill patients with many comorbidities and medical supportive devices. Tigecycline is a therapeutic option for treating this infection because of its potential ability against wide spectrum of bacterias, including multi-drug resistance A. baumannii (MDRAB). Our study determine the in vitro susceptibility of tigecycline against A. baumanii isolates and the emergence of MDRAB. The frequency of isolates that were not inhibited at MIC ≤ 0.5 µg/ml was 50.46%, at MIC = 1µg/ml was 2.38%, and at MIC = 2 µg/ml was 19.07%. The susceptibility rate of tigecycline against A. baumanii was 68.27% in 2015, 79.58% in 2016, and 67.87% in 2017. In vitro result demonstrated that tigecycline had good value of MIC against A. baumanii at the range of 0.5 to 2 µg/ml.
Comparison of 2009 and 2011 WHO Guidelines, and Scoring Models for Adult Hospitalized Dengue Infection: A Single Observation in Tangerang, Indonesia Wiwing, Veronica; Japutri, Josephine; Suryadinata, Neneng
Medicinus Vol 13, No 2 (2024): February
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v13i2.8104

Abstract

Background: World Health Organization (WHO) published a dengue guideline in 2009 and in 2011 by WHO-SEARO. However, many of dengue cases in early phase do not meet all the criteria by WHO classification. Because of this condition there is a scoring model that was published in 2015, that might help in primary health care. Therefore, a study to compare those diagnostic tools especially in adult dengue patients in Banten is needed.Aims: This study is to know the comparison between 2009 version and 2011 version of dengue diagnostic guidelines by WHO and scoring model version.Methods and Material: This study used a descriptive method with a cross-sectional design at 60 adult dengue patients. Each patient is grouped according to diagnostic tools’ classification and will be analyzed using Chi-square.Results: Results are grouped according to the WHO diagnosis from 2009 and 2011, presumptive model and probable models where there are 46 (77%), 48 (78%), 31(52%), and 15 (25%) of patients diagnosed with dengue infection. Overall, the diagnosis made by the 2009 WHO and the probable models has the most superior sensitivity and specificity values of 84,6% and 25%, and 82,4% and 97,7% respectively compared to other diagnostic tools. However, from the results of positive predictive values, probable models have a higher percentage than the 2009 WHO diagnosis.Conclusions: The probable model is more sensitive and specific than other diagnostic results. These conclude that probable model is best tool for dengue infection screening in early phase of infection.
A Case Report: Combined Sciatic Nerve and Lumbar Plexus Nerve Block in A Patient with Acute Decompensated Heart Failure Undergoing Lower Extremity Surgical Debridement Tantri, Irma Lusiana; Saroso, Natalia Frederika Darmawan Adji; Domini, Marielle Ancilla; Wiwing, Veronica
Medicinus Vol 12, No 3 (2023): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v11i1.7366

Abstract

Background: Peripheral nerve block for lower extremity surgeries requires a minimum of two block injections. Although the combination of the lumbar plexus block and the sciatica block is a procedure that requires large doses of local anesthetic, which may induce cardiotoxicity, a recent study suggests that change in the hemodynamic system is not clinically significant.Case Description: We report a case of a 53-year-old male presenting with a worsened shortness of breath two days before hospital admission. He also experienced a sudden high fever and pain on his right thigh. The patient had a history of Heart Failure (EF 28%) and Congestive liver disease and was diagnosed with right femur cellulitis with right phlegmon. Surgical debridement was planned to treat sepsis. Right lumbar plexus block and right sciatica block were performed as surgical anesthesia. The surgery duration was one hour, and the patient was transferred to the PACU. The patient was treated in ICU before being admitted to the general ward and was discharged on day three post-surgery.Conclusion: The combination of Sciatic nerve and lumbar plexus nerve block is an effective anesthesia and analgesia technique for lower limb surgery in individuals with a severe heart condition. 
In Vitro Susceptibility Of Tigecycline Among Acinetobacter Baumanii Clinical Isolates From a Hospital in Indonesia Wiwing, Veronica; Cucunawangsih, Cucunawangsih
Medicinus Vol. 7 No. 1 (2017): October 2017 - January 2018
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i1.1436

Abstract

Acinetobacter baumanii (A. baumanii) has arisen as the most important cause of nosocomial infection, typically in severely ill patients with many comorbidities and medical supportive devices. Tigecycline is a therapeutic option for treating this infection because of its potential ability against wide spectrum of bacterias, including multi-drug resistance A. baumannii (MDRAB). Our study determine the in vitro susceptibility of tigecycline against A. baumanii isolates and the emergence of MDRAB. The frequency of isolates that were not inhibited at MIC ‰¤ 0.5 µg/ml was 50.46%, at MIC = 1µg/ml was 2.38%, and at MIC = 2 µg/ml was 19.07%. The susceptibility rate of tigecycline against A. baumanii was 68.27% in 2015, 79.58% in 2016, and 67.87% in 2017. In vitro result demonstrated that tigecycline had good value of MIC against A. baumanii at the range of 0.5 to 2 µg/ml.
A Case Report: Combined Sciatic Nerve and Lumbar Plexus Nerve Block in A Patient with Acute Decompensated Heart Failure Undergoing Lower Extremity Surgical Debridement Tantri, Irma Lusiana; Saroso, Natalia Frederika Darmawan Adji; Domini, Marielle Ancilla; Wiwing, Veronica
Medicinus Vol. 12 No. 3 (2023): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v11i1.7366

Abstract

Background: Peripheral nerve block for lower extremity surgeries requires a minimum of two block injections. Although the combination of the lumbar plexus block and the sciatica block is a procedure that requires large doses of local anesthetic, which may induce cardiotoxicity, a recent study suggests that change in the hemodynamic system is not clinically significant.Case Description: We report a case of a 53-year-old male presenting with a worsened shortness of breath two days before hospital admission. He also experienced a sudden high fever and pain on his right thigh. The patient had a history of Heart Failure (EF 28%) and Congestive liver disease and was diagnosed with right femur cellulitis with right phlegmon. Surgical debridement was planned to treat sepsis. Right lumbar plexus block and right sciatica block were performed as surgical anesthesia. The surgery duration was one hour, and the patient was transferred to the PACU. The patient was treated in ICU before being admitted to the general ward and was discharged on day three post-surgery.Conclusion: The combination of Sciatic nerve and lumbar plexus nerve block is an effective anesthesia and analgesia technique for lower limb surgery in individuals with a severe heart condition. 
Comparison of 2009 and 2011 WHO Guidelines, and Scoring Models for Adult Hospitalized Dengue Infection: A Single Observation in Tangerang, Indonesia Wiwing, Veronica; Japutri, Josephine; Suryadinata, Neneng
Medicinus Vol. 13 No. 2 (2024): February
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v13i2.8104

Abstract

Background: World Health Organization (WHO) published a dengue guideline in 2009 and in 2011 by WHO-SEARO. However, many of dengue cases in early phase do not meet all the criteria by WHO classification. Because of this condition there is a scoring model that was published in 2015, that might help in primary health care. Therefore, a study to compare those diagnostic tools especially in adult dengue patients in Banten is needed.Aims: This study is to know the comparison between 2009 version and 2011 version of dengue diagnostic guidelines by WHO and scoring model version.Methods and Material: This study used a descriptive method with a cross-sectional design at 60 adult dengue patients. Each patient is grouped according to diagnostic tools’ classification and will be analyzed using Chi-square.Results: Results are grouped according to the WHO diagnosis from 2009 and 2011, presumptive model and probable models where there are 46 (77%), 48 (78%), 31(52%), and 15 (25%) of patients diagnosed with dengue infection. Overall, the diagnosis made by the 2009 WHO and the probable models has the most superior sensitivity and specificity values of 84,6% and 25%, and 82,4% and 97,7% respectively compared to other diagnostic tools. However, from the results of positive predictive values, probable models have a higher percentage than the 2009 WHO diagnosis.Conclusions: The probable model is more sensitive and specific than other diagnostic results. These conclude that probable model is best tool for dengue infection screening in early phase of infection.