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Produksi senyawa metabolit sekunder dari tumbuhan obat Aliefman Hakim; A. Wahab Jufri
Rengganis Jurnal Pengabdian Masyarakat Vol. 1 No. 1 (2021): Mei 2021
Publisher : Pendidikan Matematika, FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (330.501 KB) | DOI: 10.29303/rengganis.v1i1.25

Abstract

Secondary metabolites were needed by researchers as raw materials for drugs, raw materials for the synthesis of target molecules, bioactive compounds, and model compounds. But until now, there were no producers that supply secondary metabolite compounds in Indonesia, so it is very difficult to find them in the domestic market. The need for secondary metabolite compounds has been purchased from abroad at very high prices. On the other hand, Indonesia has a lot of plant diversity which is the source of secondary metabolite compounds. Modification of several procedures for isolation of secondary metabolites has been carried out in the framework of the production of secondary metabolites.
Solvent Optimization for Extraction Mesua ferrea L. Leaves As An Antioxidant Using Simplex Lattice Design Method Handa Muliasari; Luh Putu Intan Paramitha Sari; Aliefman Hakim
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 5 No 1 (2022)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v5i1.29302

Abstract

Mesua ferrea L. leaves methanol extract has the highest antioxidant activity than the other part of the plant. However methanol is toxic solvent, so the using of methanol for extraction may harmful for health and environment. The purpose of this study was to optimize the solvent combination of ethanol and water for extraction of Mesua ferrea L. leaves by using Simplex Lattice Design (SLD) method. The samples were extracted by Ultrasonic Assisted Extraction (UAE) using variation of solvents ethanol 96%, ethanol 50% and water. The solvent combination was optimized by using SLD method based on the Total Phenolic Content of all crude extract. The result showed that the TPC of ethanol 96%, ethanol 50% and water crude extracts were 574.7±66.97 mgGAE/g, 657.8±37.02 mgGAE/g and 524.23±14.48 mgGAE/g respectively. SLD was calculated and the optimal solvent obtained was ethanol 55% with TPC of 626.235± 23 mgGAE/g. The ethanol 55% extract of Mesua ferrea L. leaves has strong antioxidant activity (IC50 57.77) ppm using DPPH method.
Profile of Attitudes of Science Teacher Candidates Towards Indigenous Science-Based Science Learning Agus Muliadi; Joni Rokhmat; Aliefman Hakim; AA Sukarso
Prisma Sains : Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Vol 11, No 2: April 2023
Publisher : IKIP Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/j-ps.v11i2.8199

Abstract

The study aims to explore the attitudes of science teacher candidates towards indigenous science-based science learning. This study is an exploratory research conducted in three study programs that provide science teacher education, namely Biology, Chemistry, and Physics Education with 53 research subjects. This study uses a research instrument in the form of a closed questionnaire with answers using a Likert scale and has been validated by experts. The research data were analyzed using quantitative descriptive statistics and inferential statistics Anova test and t-test. The results of this study are (1) the attitude of students in the biology education study program has an average score of 3,29 in the Good category, physics education is 3,00 in the Good category, and chemistry education is 3,13 in the Good category; (2) the attitude of male students has an average score of 3,21 in the Good category and 3,28 for women in the Good category; (3) there is no significant difference in the attitudes of students of biology, chemistry, physics education study programs towards indigenous science-based science learning in songket cloth motifs, as evidenced by the significance value of the Anova test of 0,507>0,05; (4) there is no significant difference in the attitudes of male and female students towards indigenous science-based learning in the songket cloths motifs, as evidenced by the significance value of the t-test of 0,455>0,05.