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Produksi senyawa metabolit sekunder dari tumbuhan obat Aliefman Hakim; A. Wahab Jufri
Rengganis Jurnal Pengabdian Masyarakat Vol. 1 No. 1 (2021): Mei 2021
Publisher : Pendidikan Matematika, FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (330.501 KB) | DOI: 10.29303/rengganis.v1i1.25

Abstract

Secondary metabolites were needed by researchers as raw materials for drugs, raw materials for the synthesis of target molecules, bioactive compounds, and model compounds. But until now, there were no producers that supply secondary metabolite compounds in Indonesia, so it is very difficult to find them in the domestic market. The need for secondary metabolite compounds has been purchased from abroad at very high prices. On the other hand, Indonesia has a lot of plant diversity which is the source of secondary metabolite compounds. Modification of several procedures for isolation of secondary metabolites has been carried out in the framework of the production of secondary metabolites.
Solvent Optimization for Extraction Mesua ferrea L. Leaves As An Antioxidant Using Simplex Lattice Design Method Handa Muliasari; Luh Putu Intan Paramitha Sari; Aliefman Hakim
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 5 No 1 (2022)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v5i1.29302

Abstract

Mesua ferrea L. leaves methanol extract has the highest antioxidant activity than the other part of the plant. However methanol is toxic solvent, so the using of methanol for extraction may harmful for health and environment. The purpose of this study was to optimize the solvent combination of ethanol and water for extraction of Mesua ferrea L. leaves by using Simplex Lattice Design (SLD) method. The samples were extracted by Ultrasonic Assisted Extraction (UAE) using variation of solvents ethanol 96%, ethanol 50% and water. The solvent combination was optimized by using SLD method based on the Total Phenolic Content of all crude extract. The result showed that the TPC of ethanol 96%, ethanol 50% and water crude extracts were 574.7±66.97 mgGAE/g, 657.8±37.02 mgGAE/g and 524.23±14.48 mgGAE/g respectively. SLD was calculated and the optimal solvent obtained was ethanol 55% with TPC of 626.235± 23 mgGAE/g. The ethanol 55% extract of Mesua ferrea L. leaves has strong antioxidant activity (IC50 57.77) ppm using DPPH method.
Profile of Attitudes of Science Teacher Candidates Towards Indigenous Science-Based Science Learning Agus Muliadi; Joni Rokhmat; Aliefman Hakim; AA Sukarso
Prisma Sains : Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Vol 11, No 2: April 2023
Publisher : IKIP Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/j-ps.v11i2.8199

Abstract

The study aims to explore the attitudes of science teacher candidates towards indigenous science-based science learning. This study is an exploratory research conducted in three study programs that provide science teacher education, namely Biology, Chemistry, and Physics Education with 53 research subjects. This study uses a research instrument in the form of a closed questionnaire with answers using a Likert scale and has been validated by experts. The research data were analyzed using quantitative descriptive statistics and inferential statistics Anova test and t-test. The results of this study are (1) the attitude of students in the biology education study program has an average score of 3,29 in the Good category, physics education is 3,00 in the Good category, and chemistry education is 3,13 in the Good category; (2) the attitude of male students has an average score of 3,21 in the Good category and 3,28 for women in the Good category; (3) there is no significant difference in the attitudes of students of biology, chemistry, physics education study programs towards indigenous science-based science learning in songket cloth motifs, as evidenced by the significance value of the Anova test of 0,507>0,05; (4) there is no significant difference in the attitudes of male and female students towards indigenous science-based learning in the songket cloths motifs, as evidenced by the significance value of the t-test of 0,455>0,05.
Analysis Of Science Concepts On Physical And Chemical Changes In The Mamaq Tradition Of The Sasak Ethnic Group Fahmi Firdaus; Maulidatin Nanisfi; Siti Diniah; X Zardht Alex Hidayat; Yayuk Andayani; Aliefman Hakim; Saprizal Hadisaputra
Indonesian Journal of Educational Innovation Vol. 1 No. 1 (2025): April
Publisher : Yayasan Siti Widhatul Faeha Salahudin Syawal

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Mamaq is a traditional practice passed down through generations of the Sasak tribe. Analysing the idea of science in relation to the physical and chemical alterations in the Sasak tribe’s mamaq tradition is the goal of this study. This research uses a qualitative approach with a descriptive research type to explore in-depth knowledge about the mamaq tradition of the Sasak tribe. Direct observation and interviews were used to get data from community leaders and cultural figures, as well as secondary data from various relevant written sources. The analysis results found several scientific concepts in the mamaq tradition related to physical and chemical changes, including: 1) The betel nut that is cut, there is a physical change in the structure of the betel nut from a round shape to small pieces. 2) The betel leaves that are folded, there is a change in the shape of the leaves into a square fold. 3) There is a transition from a solid to a liquid texture in the ground mamaq substance. 4) The combination of mamaq components, where the chemicals in the finely ground substances generate a red colour. Thus, it may be said that the physical and chemical changes in the Sasak tribe’s mamaq tradition contain a scientific concept
Natural Science Mini Project Practicum through The Practical Instructions Module for Identifying Natural Chemicals in Medicinal Plants Bakhtiar Ardiansyah; Agus Ramdani; Aliefman Hakim; Muh Makhrus
International Journal of Contextual Science Education Vol. 1 No. 1 (2023): October - December 2023
Publisher : Postgraduate Program, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/ijcse.v1i1.552

Abstract

21st century learning includes achieving the ability to communicate, think critically, think and act creatively, and collaborate. One of the efforts recommended by experts to achieve this is through the application of project-based learning. Various forms of blending are implemented using project-based learning. One form of method in project-based learning is the practicum method. This literature review aims to describe various forms of project-based learning as well as the development of practical guide modules and their relationship to several practical activities that lead to the chemical identification of natural medicinal plant ingredients. The various results of this research will give birth to alternative project-based learning by developing practical guide modules that can strengthen students' understanding of high-level thinking skills related to the classification of living things, especially plants, as well as science process skills and scientific attitudes.
Analisis Kreativitas Ilmiah Mahasiswa pada Mata Kuliah Farmakognosi Berbasis Praktikum Sri Idawati; Aliefman Hakim; Agus Abhi Purwoko; Wahab Jufri; Joni Rokhmat; AA Sukarso
Jurnal Penelitian Pendidikan IPA Vol 11 No 8 (2025): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i8.11982

Abstract

Scientific creativity is an important competency in Higher Education, especially in the fields of science and technology. This research aims to analyze the level of scientific creativity of D-III Pharmacy students in practicum-based Pharmacognosy courses. In Torrance's indicators, there are four indicators used to measure the level of scientific creativity of students, namely fluency, flexibility, originality, and elaboration. The research method used is quantitative descriptive method with data collection through observation, and questionnaire forms. The research subjects were 3rd semester (odd) pharmacy D-III study program students with a total of 30 students. The results showed that the level of scientific creativity of students tended to be in the less category. As for the level of student creativity in each Torrance indicator, namely fluency is in the medium category (51%), originality is in the less category (23%), flexibility is in the less category (25%), and elaboration is in the less category (26%).
Ethnoscience-Project-Based Learning (E-PjBL) Model for Biology Education: Content and Construct Validity Analysis Agus Muliadi; Joni Rokhmat; Aliefman Hakim; AA Sukarso
Jurnal Penelitian Pendidikan IPA Vol 11 No 10 (2025): October
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i10.13055

Abstract

This study aims to analyze the content and construct validity of the Ethnoscience–Project-Based Learning (E-PjBL) model for biology education in higher education. The study employed a Research and Development (R&D) approach guided by Nieveen’s educational design framework, focusing on the initial validation stage of model development. The validation process involved six expert validators with expertise in biology education, ethnoscience, instructional model development, and educational research. Research instruments consisted of content validity and construct validity validation sheets using a five-point Likert scale. The collected data were analyzed using descriptive quantitative analysis by calculating mean validity scores and inter-rater reliability using the percentage of agreement method. The results of the study indicate that: (1) the content validity of the E-PjBL model is categorized as very valid, with an overall mean score of 4.97, indicating that the model is developed based on actual learning needs and supported by state-of-the-art theoretical and empirical foundations; (2) the construct validity of the E-PjBL model is also classified as very valid, with an overall mean score of 4.91, demonstrating strong internal consistency among model components, including instructional syntax, learning objectives and impacts, as well as the learning environment and social system. These findings provide empirical evidence that the E-PjBL model is conceptually sound and theoretically feasible for further testing at the stages of practicality and effectiveness in higher education biology learning