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DIAGNOSIS DAN TATA LAKSANA ENSEFALITIS HERPES SIMPLEKS Yuliantini, Tri; Suwarba, IGN Made; Kari, Komang; Mahalini, Dewi Sutriani
Medicina Vol 44 No 3 (2013): September 2013
Publisher : Medicina

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Abstract

Infeksi Herpes simpleks pada susunan saraf pusat (SSP) merupakan infeksi SSP yang paling beratdan sering berakibat fatal. Angka kejadiannya diperkirakan 1 kasus per 250 000 sampai 500 000orang per tahun, sepertiganya terjadi pada anak-anak. Gejala dan tanda klinis pada fase awal sangattidak khas. Pemberian terapi yang terlambat membawa dampak terjadinya kecacatan permanen.Deteksi virus Herpes simpleks (VHS) di dalam cairan serebrospinal dengan polymerase chain reactionmerupakan modalitas pilihan untuk diagnosis ensefalitis herpes simpleks (EHS). Asiklovir intravenamerupakan obat pilihan pertama. Pengobatan segera diberikan kepada pasien yang dicurigai menderitaEHS, kemudian pengobatan dapat dilanjutkan atau dihentikan sesuai konfirmasi laboratorium atauhasil biopsi otak. Pasien yang tidak diberikan antivirus atau pengobatannya terlambat angkakematiannya cukup tinggi.
A 44-DAY OLD MALE INFANT WITH THORACOABDOMINAL ECTOPIA CORDIS OF PENTALOGY CANTRELL’S SYNDROME Yuliantini, Tri; Gunawijaya, Eka; Putu Yasa, Ketut
Medicina Vol 44 No 1 (2013): Januari 2013
Publisher : Medicina

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Abstract

Ectopia cordis is a rare and impressive congenital abnormality, occurring in 5.5 to 7.9 per 1 million live births. The defect is characterized by partial or complete displacement of the heart out of the thoracic cavity. This defect require a staged procedure to achieve a complete repair. We reported a 44-day-old male infant presented with symptoms of tachypnea and mild cyanosis since birth. On physical examination, the child looked lethargic with a weak cry. The midline defect extended from the lower margin of the neck to the umbilicus. The sternum was completely bifid, with an inter-ridge distance of 6 cm, through which the heart was protruded for 4-5 cm and the apex pointed anteriorly. The first and second heart sounds were normal with ejection holosystolic murmur. The diagnosis was ectopia cordis. A two dimensional echocardiography showed complete atrioventricular septal defect, which was known as a group of cyanotic congenital heart defect. The infant was referred subsequently to the neonatal intensive care unit with the ventilator support. Historically, the prognosis of this condition is poor. Our patient died before surgery being performed.
Co-Authors Dewi Sutriani Mahalini Eka Gunawijaya I Gusti Ngurah Made Suwarba Ketut Putu Yasa Komang Kari