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All Journal Indonesian Journal of Urology Mutiara Medika: Jurnal Kedokteran dan Kesehatan MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Journal of Comprehensive Science
Yuningtyaswari Yuningtyaswari
Department of Histology, Faculty of Medicine and Health Science/Muhammadiyah University, Yogyakarta.
Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Electrical & Electronics Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Medicine & Pharmacology Public Health

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Journal : Journal of Comprehensive Science

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Pengaruh Ekstrak Rambut Jagung (Zea mays L.) Terhadap Gambaran Histologi Ginjal Tikus Putih yang Diinduksi Alkohol (Studi in vivo pada Rattus norvegicus) Yuningtyaswari, Yuningtyaswari; Fitria Hidayati, Ashfi
Journal of Comprehensive Science Vol. 4 No. 2 (2025): Journal of Comprehensive Science (JCS)
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v4i2.3006

Abstract

Alcoholic beverages contain ethanol, which is toxic and can increase oxidative stress, potentially damaging the kidneys. Corn silk contains flavonoids with antioxidant effects. This study aims to examine the effect of corn silk extract on the kidney histology of alcohol-induced white rats. This experimental study used a post-test only control group design with 36 rats divided into 9 groups: control (C), negative control (P) receiving 1 ml/day of alcohol, positive control (J1, J2, J3) receiving corn silk extract at doses of 50, 100, and 150 mg/KgBW, treatment groups (PJ1, PJ2, PJ3) induced with alcohol and then given corn silk extract, and the comparator group (S) induced with alcohol and given 1 ml of vitamin C. Kidney histological damage was assessed based on glomerular and tubular damage scores. Data were analyzed using One Way ANOVA and post hoc Duncan tests. The results showed the average kidney damage scores for groups C = 43.35; P = 54.55; J1 = 46.75; J2 = 47.20; J3 = 46.45; PJ1 = 50.75; PJ2 = 46.35; PJ3 = 47.20; and S = 46.90. The glomerular and tubular damage scores of group C differed significantly from P but were not significantly different from other groups. Thus, the administration of corn silk extract (Zea mays L.) does not have a significant effect on the histological appearance of the glomerulus and renal tubules in alcohol-induced white rats (Rattus norvegicus). However, there is a tendency indicating that this extract has the potential to reduce alcohol-induced damage, although the observed differences are not statistically significant.
The Effect of Using Absorbent Carbon on Air Exposed to Air Fresheners on The Histology of The Cornea of The White Rat (Rattus Novergicus) Yuningtyaswari, Yuningtyaswari; Susanti, Tisa
Journal of Comprehensive Science Vol. 3 No. 8 (2024): Journal of Comprehensive Science (JCS)
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v3i8.854

Abstract

Air freshener contain hazardous chemical such as formaldehyde. Absorbent carbon is used as an adsorbent to reduce air pollution. The goal of this research is to know the use of absorbent carbon to cornea histology on Rattus novergicus that was induced with air freshener. This research was an experimental study with a post-test only control group. The subjects were 28 one-month old male Rattus novergicus Wistar strains divide into 4 groups: Control (K), air freshener (P1), absorbent carbon (P2) and air freshener plus absorbent carbon (P3).The treatment was performed 8 hours/day for 35 days. Data of anterior epithelial thickness were analyzed by One Way Anova test. Data of the overall thickness of the corneal layer and keratocyte number were analyzed by Kruskal Wallis test. The overall thickness of the corneal layer and anterior epithelial thickness showed that there were not significant difference between subject groups (p>0,05). Anterior epithelial thickness showed that there were not significant difference between subject groups (p>0,05). Keratocyte number showed significant difference between subject groups (p<0,05), Mann Whitney test for Keratocyte number showed results P1>P3>K>P2 Absorbent carbon gives postitive effect to reduce cornea damage on Rattus novergicus that induced by air freshener.
Co-Authors Ahmad Hamim Sadewa Fitria Hidayati, Ashfi Haryani, Asti Marsetyawan HNE Soesatyo Muhartiningsih, Sitilia Susanti, Tisa Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati