Yardi Saibi
Program studi Farmasi Fakultas Ilmu Kesehatan UIN Syarif Hidayatullah Jakarta

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Potensi Interaksi Obat Pada Resep Pasien Diabetes Melitus Rawat Jalan di RS X Jakarta Pusat Khalida Handayani; Yardi Saibi
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 1, No 1 (2019)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (186.883 KB) | DOI: 10.15408/pbsj.v1i1.12853

Abstract

 Interaksi obat merupakan bagian dari masalah terkait obat yang dapat mempengaruhi terapi pasien. Kemungkinan interaksi obat meningkat 2,5 kali lipat untuk setiap obat yang ditambahkan dalam resep pasien. Pasien diabetes melitus termasuk yang rentan terhadap kejadian interaksi obat. Penelitian ini bertujuan  untuk mengetahui gambaran potensi interaksi obat pada peresepan obat antidiabetik oral di RS X Jakarta Pusat periode Januari sampai Maret 2014. Desain penelitian ini adalah cross sectional dengan rancangan deskriptif dan data diambil secara retrospektif. Seluruh resep yang yang mengandung obat antidiabetes oral dijadikan populasi. Besaran sampel dihitung dengan rumus Slovin. Pengambilan sampel dilakukan secara acak. Analisa data dilakukan secara univariat untuk mendeskripsikan persentase kejadian interaksi obat dan analisa bivariat dilakukan dengan menggunakan uji statistik kai kuadrat . Dari total 310 resep yang menjadi sampel, terdapat 56,13% resep yang berpotensi mengalami interaksi obat dengan 79,24% interaksi terdapat pada resep dengan ≥5 obat. Mekanisme interaksi secara farmakodinamik mendominasi dengan 214 kasus (40,30%). Uji statistik memperlihatkan terdapat hubungan bermakna antara jumlah obat yang ada dalam resep dengan potensi  interaksi obat yang teridentifikasi (p<0,05). Hasil odds ratio menunjukan bahwa pasien yang menerima jumlah obat ≥5 beresiko 10,278 kali lebih tinggi mengalami potensi interaksi obat (95% CI, 5.933-17.806). Potensi interaksi obat pada resep pasien rawat jalan di RS X Jakarta masih cukup tinggi. Apoteker perlu melakukan skrining terhadap resep pasien diabetes melitus sebagai bagian dari pelaksanaan standar pelayanan kefarmasian khususnya dalam mendeteksi potensi interaksi obat   
Profil Pemberian Informasi ObatTerhadap Pasien dengan Resep Antidiabetes di Apotek Tangerang Selatan Nelly Suryani; Yardi Saibi; Vidia Arlaini Anwar
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 2, No 1 (2020)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (198.016 KB) | DOI: 10.15408/pbsj.v2i1.15280

Abstract

Providing drug information is very important to be conducted by pharmacists for patients who redeem drugs at their pharmacy, especially patients who fall into the priority category for counseling such as patients undergoing diabetes mellitus treatment. This study aimed to create a profile of drug / counseling information given by pharmacies in the South Tangerang area to patients with prescription of antidiabetic drugs. This was a descriptive cross sectional study. Data were collected by the simulation patient method played by 6 seniorundergraduate pharmacy students. Simple random sampling was used in taking 100 pharmacies from the population of pharmacies registered at the city health office. The scenario was in the form of a new prescription contained of 5 mg of glibenclamide without repetition which was intended for family member of the simulated patient. To identify officers who provided drug information, simulation patients asked confirmation questions to ascertain whether they were pharmacists or not. The results showed that as many as 88.65% of officers who provided drug information to simulated patients were non-pharmacists. The most commonly given information by the pharmacist was the frequency of drug use followed by the time of use and the purpose of use (indications) which were 100%, 90.91% and 54.55%, respectively. While the information items provided by non-pharmacists were the frequency of drug use followed by the intended use and time of use associated with meal times which were 83.72%, 61.63% and 40.70% respectively. It can be concluded that more the drug information provided to patients is carried out by unappropriate professionals namely pharmacists. Drug information delivered to patients both by pharmacists and by non-pharmacists is not maximally done. The role of pharmacists in providing drug information to DM patients needs to be increased