Article Per Year (5 Year)
p-Index From 2020 - 2025
0.817
P-Index
This Author published in this journals
All Journal EduChemia: Jurnal Kimia dan Pendidikan Pharmaceutical And Biomedical Sciences Journal (PBSJ)
Marvel Marvel Marvel
Department Of Pharmacy, Faculty Of Health Sciences, UIN Syarif Hidayatullah Jakarta, Banten, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Gambaran Karakteristik Pasien dan Penggunaan Obat Dispepsia Di Klinik A Daerah Bekasi Timur Intan Suri; Marvel Marvel; Nurmeilis Nurmeilis
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 2, No 2 (2020)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (259.486 KB) | DOI: 10.15408/pbsj.v2i2.19141

Abstract

Perubahan gaya hidup dan pola makan menjadi salah satu penyebab terjadinya gangguan saluran pencernaan. Gangguan pencernaan yang paling banyak diderita adalah dispepsia. Dalam hal ini banyak faktor risiko yang menyebabkan terjadinya kekambuhan dispepsia. Penelitian ini bertujuan untuk mengetahui gambaran karakteristik pasien dan penggunaan obat dispepsia di klinik A daerah Bekasi Timur. Penelitian ini dilakukan dengan metode cross sectional dengan metode pengambilan data secara retrospektif melalui rekam medik pasien. Pemilihan sampel dengan menggunakan teknik total sampling dimana terdapat 200 sampel yang memenuhi kriteria inklusi dalam penelitian. Hasil penelitian menunjukkan Karakteristik pasien dispepsia di Klinik A Daerah Bekasi Timur yang dominan adalah berjenis kelamin perempuan (60%), berada pada rentang umur ≥ 56 tahun (27,5%), tanpa ada penyakit penyerta (76,5%), jenis penyakit penyerta hipertensi (46,42%), frekuensi kedatangan pasien 1 kali (64,5%), dan penggunaan obat dispepsia dengan 3 kombinasi (57%). Dari hasil uji statistik dihasilkan pernyataan bahwa jenis kelamin, umur tidak mempunyai hubungan yang bermakna dengan frekuensi dispepsia (p > 0,05). Penyakit penyerta mempunyai hubungan yang bermakna dengan frekuensi dispepsia (p < 0,05). Jenis kelamin, umur, penyakit penyerta tidak mempunyai hubungan yang bermakna dengan penggunaan obat dispepsia (p > 0,05). Frekuensi dispepsia mempunyai hubungan yang bermakna dengan obat dispepsia (p < 0,05).
Analisis Hubungan Petugas Apotek Terhadap Pelayanan Informasi Obat Kontrasepsi Oral Marvel Marvel
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.28108

Abstract

The successful implementation of the Family Planning (Keluarga Berencana) program assists the government in developing reproductive health. The acceptors' knowledge about oral contraceptive drugs may be influenced by drug information conveyed by pharmacy staff, namely pharmacists and their assistants. Therefore, this study aimed to measure relationship between pharmacy staff and information services for oral contraceptives at the South Tangerang Regional Pharmacy using a cross-sectional design. This study used trained simulated patients. The samples surveyed were 152 pharmacies with 132 pharmaceutical technical personnel, and 20 pharmacists as respondent. In terms of drug information services, this study found 94 subjects in the poor category (value of 69.9%), 44 subjects (26.4%) in the moderate category (value between 70-79.9%), and 14 subjects (7.9%) in the good category (value of 80%). There was a significant relationship between the pharmacy staff variable with the total value of drug information services (Pelayanan Informasi Obat) variable (p = 0.016). The result showed that pharmacists provide information services for oral contraceptives better than pharmacy technicians.
Antidiabetic Activities In Vitro and In Silico of Nonpolar Compounds in Patat Leaves (Phrynium capitatum) Wijayanti, Laras; Marvel, Marvel; Ma’arif, Samsul; Fathoni, Ahmad
EduChemia: Jurnal Kimia dan Pendidikan Vol 9, No 1 (2024)
Publisher : Department of Chemical Education Faculty of Teacher Training and Education Universitas Su

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30870/educhemia.v9i1.21935

Abstract

One form of Indonesian cultural wisdom is the use of leaves as food packaging. In addition to being used as a packaging material, patat leaves are also believed to have antidiabetic benefits. Antidiabetic activity can be assessed through the enzyme α-glucosidase inhibitory activities. In this research, an in vitro and in silico analysis of antidiabetic activity was conducted for the first time on nonpolar extracts of patat leaves. In vitro analysis was conducted using the α-glucosidase enzyme inhibition method, compound analysis was conducted using GC‒MS/MS, and an in silico study was conducted via the molecular docking method to the α-glucosidase receptor (PDB: 3W37). The results showed that the nonpolar extract (n-hexane) had very weak antidiabetic activity (with an IC50 >> 100 ppm). However, the sample inhibited α-glucosidase enzyme activity by up to 86.91%. GC‒MS/MS analysis confirmed the presence of 19 compounds in the nonpolar extract of the patat leaves. Straight-chain hydrocarbons dominate the compounds. The compound with the greatest abundance was Octadecyl 2,2,2-trifluoroacetate (RT 33.908; 9.53% area). An in silico test revealed that the compound with the greatest potential as an antidiabetic agent was γ-methylionone (40.78 μM). On the basis of the results of this theoretical approach, the compound can be further analyzed to validate its activity.
Analisis Hubungan Petugas Apotek Terhadap Pelayanan Informasi Obat Kontrasepsi Oral Marvel Marvel
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.28108

Abstract

The successful implementation of the Family Planning (Keluarga Berencana) program assists the government in developing reproductive health. The acceptors' knowledge about oral contraceptive drugs may be influenced by drug information conveyed by pharmacy staff, namely pharmacists and their assistants. Therefore, this study aimed to measure relationship between pharmacy staff and information services for oral contraceptives at the South Tangerang Regional Pharmacy using a cross-sectional design. This study used trained simulated patients. The samples surveyed were 152 pharmacies with 132 pharmaceutical technical personnel, and 20 pharmacists as respondent. In terms of drug information services, this study found 94 subjects in the poor category (value of 69.9%), 44 subjects (26.4%) in the moderate category (value between 70-79.9%), and 14 subjects (7.9%) in the good category (value of 80%). There was a significant relationship between the pharmacy staff variable with the total value of drug information services (Pelayanan Informasi Obat) variable (p = 0.016). The result showed that pharmacists provide information services for oral contraceptives better than pharmacy technicians.
Co-Authors Agusdini Banun Saptaningsih Anton Bahtiar Bahtiar Fathoni, Ahmad Intan Suri Ma’arif, Samsul Nurmeilis Nurmeilis Wijayanti, Laras