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Aurelia Stephanie
Rumah Sakit Otorita Batam, Sekupang, Batam, Indonesia
Health Professions Medicine & Pharmacology Public Health

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Sindrom Stevens-Johnson Diduga Akibat Fenitoin Aurelia Stephanie; Eny Susilowati
Cermin Dunia Kedokteran Vol 45, No 4 (2018): Cedera Kepala
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i4.666

Abstract

Sindrom Stevens-Johnson (SSJ) merupakan bagian dari nekrolisis epidermis (NE) yaitu sindrom reaksi mukokutan akut yang ditandai dengan nekrosis dan pengelupasan epidermis yang luas. Diaporkan seorang perempuan, usia 21 tahun, datang ke UGD rumah sakit dengan keluhan demam dan timbul ruam-ruam merah yang kemudian berisi air sejak 3 hari. Setelah konsumsi fenitoin, timbul bercak merah disertai gatal di daerah paha, tungkai dan punggung. Dua hari kemudian bercak merah tersebut mulai berisi cairan berdinding kendur dan menyebar ke seluruh tubuh. Pada hari ke-9 perawatan, pasien mengalami perbaikan klinis dan boleh pulang.Stevens-Johnson Syndrome (SJS) is a type of epidermal necrolysis (NE) , a syndrome of acute mucocutaneus reaction recognized by widespread necrosis and epidermal lysis. A case of 21 year-old female, presented in emergency with fever and reddish rash followed by vesicles since 3 days. After phenytoin consumption, reddish spots with urticaria were observed in thigh, legs and back. Two days later, they were followed with vesicles spreading to whole body. Clinical improvement was observed after 9 days, and the patient was discharged.
Sindrom Stevens-Johnson Diduga Akibat Fenitoin Aurelia Stephanie; Eny Susilowati
Cermin Dunia Kedokteran Vol 45 No 4 (2018): Neurologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i4.801

Abstract

Pendahuluan: Sindrom Stevens-Johnson (SSJ) merupakan bagian dari nekrolisis epidermis (NE), yaitu sindrom reaksi mukokutan akut yang ditandai dengan nekrosis dan pengelupasan epidermis yang luas. Dilaporkan seorang perempuan, usia 21 tahun, datang ke UGD rumah sakit dengan keluhan demam dan timbul ruam-ruam merah yang kemudian berisi air sejak 3 hari. Setelah konsumsi fenitoin, timbul bercak merah disertai gatal di daerah paha, tungkai, dan punggung. Dua hari kemudian bercak merah tersebut mulai berisi cairan berdinding kendur dan menyebar ke seluruh tubuh. Pada hari ke-9 perawatan, pasien mengalami perbaikan klinis dan boleh pulang.   Introduction: Stevens - Johnson syndrome (SJS) is a type of epidermal necrolysis (NE), a syndrome of acute mucocutaneus reaction recognized by widespread necrosis and epidermal lysis. A case of 21 year-old female, presented in emergency with fever and reddish rash followed by vesicles since 3 days. After phenytoin consumption, reddish spots with urticaria were observed in thigh, legs and back. Two days later, they were followed with vesicles spreading to whole body. Clinical improvement was observed after 9 days, and the patient was discharged.
Sindrom Stevens-Johnson Diduga Akibat Fenitoin Aurelia Stephanie; Eny Susilowati
Cermin Dunia Kedokteran Vol 45 No 4 (2018): Neurologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i4.801

Abstract

Pendahuluan: Sindrom Stevens-Johnson (SSJ) merupakan bagian dari nekrolisis epidermis (NE), yaitu sindrom reaksi mukokutan akut yang ditandai dengan nekrosis dan pengelupasan epidermis yang luas. Dilaporkan seorang perempuan, usia 21 tahun, datang ke UGD rumah sakit dengan keluhan demam dan timbul ruam-ruam merah yang kemudian berisi air sejak 3 hari. Setelah konsumsi fenitoin, timbul bercak merah disertai gatal di daerah paha, tungkai, dan punggung. Dua hari kemudian bercak merah tersebut mulai berisi cairan berdinding kendur dan menyebar ke seluruh tubuh. Pada hari ke-9 perawatan, pasien mengalami perbaikan klinis dan boleh pulang.   Introduction: Stevens - Johnson syndrome (SJS) is a type of epidermal necrolysis (NE), a syndrome of acute mucocutaneus reaction recognized by widespread necrosis and epidermal lysis. A case of 21 year-old female, presented in emergency with fever and reddish rash followed by vesicles since 3 days. After phenytoin consumption, reddish spots with urticaria were observed in thigh, legs and back. Two days later, they were followed with vesicles spreading to whole body. Clinical improvement was observed after 9 days, and the patient was discharged.
Co-Authors Eny Susilowati