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Saryono Saryono
Fakultas FMIPA Universitas Riau Kampus Bina widya Panam KM 12.5 Pekanbaru
Earth & Planetary Sciences Environmental Science

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Uji Bioaktivitas Antibakteri Senyawa murni dari Jamur Endofit Sporothrix sp Terhadap Bakteri Escherichia coli dan Staphylococcus aureus Dewi Yudiana Shinta; Yusmarini Yusmarini; Herix Sonata MS; Hilwan Yuda Teruna; Saryono Saryono
Dinamika Lingkungan Indonesia Vol 6, No 1 (2019)
Publisher : Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (118.154 KB) | DOI: 10.31258/dli.6.1.p.37-44

Abstract

Modern medicines that are developing now come from active ingredients isolated from plants that require large amounts of plants. The development of new drugs from endophytic fungi found obstacles in the amount of pure compounds produced. Therefore further research is needed by using endophytic fungi as a new antimicrobial producer. This study aims to see the ability or activity of pure compounds produced by Sporothrix sp endophytic fungi from Dahlia tuber (Dahlia variabilis). Test the activity of pure compounds produced by Sporothrix sp. Endophytic fungi on E. coli and Staphylococcus aureus determined by disc diffusion method. With doses of 10, 30 and 50μg/disk. In Escherichia coli bacteria doses 10 and 50μg/disk gave significant inhibition of pure compounds from isolation compared to the positive control of ciprofloxacin, which was marked by a statistically significant test result (p <0.05). In contrast to Staphylococcus aureus there was no significant difference in doses of both doses of 10.30 and 50μg/disk. Determination of pure compounds was carried out by HPLC and Infra Red Spectrophotometry.
Co-Authors Herix Sonata MS Hilwan Yuda Teruna Shinta, Dewi Yudiana Yusmarini Yusmarini