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Formulasi Sediaan Tablet Parasetamol dengan Pati Buah Sukun (Artocarpus communis) Sebagai Pengisi Dwi Elfira Kurniati; Mirhansyah Ardana; Rolan Rusli
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 5 (2017): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (687.907 KB) | DOI: 10.25026/mpc.v5i1.224

Abstract

Penggunaan pati sebagai bahan pengisi umum digunakan dalam pembuatan tablet guna menyempurnakan bentuk tablet. Penelitian ini bertujuan untuk memformulasi dan mengevaluasi kualitas granul dan sifat fisik sediaan tablet parasetamol menggunakan pati sukun sebagai bahan. Pati dibuat dengan cara dekantasi dan pengeringan. Empat formula sediaan tablet (F1, F2, F3, dan F4) dibuat menggunakan metode granulasi basah dengan bobot 575mg (F1), 600mg (F2), 650mg (F3), dan 700mg (F4) dengan menggunakan pati sebesar 4,3% (F1), 8,3% (F2), 15,3% (F3), dan 21,4% (F4). Evaluasi kualitas granul, meliputi pengujian laju alir, sudut istirahat, densitas dan indeks kompresibilitas. Sedangkan evaluasi sifat fisik tablet meliputi pengujian keseragaman ukuran, keseragaman bobot, waktu hancur dan friabilitas. Hasil penelitian menunjukkan bahwa evaluasi kualitas granul memenuhi persyaratan laju alir, sudut istirahat, dan indeks kompresibilitas, tetapi tidak memenuhi syarat distribusi ukuran partikel. F1 dan F2 dapat dikempa. F2 tidak memenuhi syarat friabilitas namun memenuhi syarat keseragaman bobot, ukuran dan waktu hancur. F1 memenuhi semua syarat uji sifat fisik tablet
GAMBARAN PENGGUNAAN OBAT TRADISIONAL UNTUK PENYAKIT HIPERTENSI PADA MASYARAKAT KELURAHAN BUDAYA PAMPANG KECAMATAN SAMARINDA UTARA Septiana Dewi; Dwi Elfira Kurniati; Lizma Febrina
Jurnal Ilmiah Manuntung Vol 10 No 2 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i2.866

Abstract

The Budaya Pampang community still adheres to the tradition of using traditional medicine. This is interesting to study, especially in hypertension which has a high prevalence. This study aims to determine the characteristics of the Budaya Pampang Village community who use traditional medicine for hypertension and the pattern of using traditional medicine for hypertension in the community. This research is a descriptive study with total sampling technique. Data collection was carried out using a questionnaire given to 48 respondents. Data were analyzed by descriptive statistics using SPSS. The results showed that the characteristics of the most respondents were male (54.2%), aged >45 years (81.2%), elementary school education (41.7%), housewife occupation (39.6%), duration of hypertension >1 year (77.1%), and duration of taking traditional medicine >1 year (64.6%). The most widely used plant type was bay leaf (16.7%), the most common dosage form was fresh preparation (91.7%), the most common processing method was boiling (68.7%), the frequency of use was 2x a day (43.8%). The reason for using traditional medicine is because it is cheaper (89.6%), easy to obtain or grow yourself (81.3%), and easy to prepare or mix (79.2%). Based on the results of the study, there are 16 species of medicinal plants with antihypertensive properties that can be the basis for drug development in the future.