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Fika Aryati
Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis” Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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Optimasi Formula Spray Gel Ekstrak Bawang Tiwai (Eleutherine americana (Aubl) Merr) Maulidya Maulidya; Fika Aryati; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 11 (2020): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (461.435 KB) | DOI: 10.25026/mpc.v11i1.386

Abstract

The ethanolic extract from the bulb of Eleutherine americana has the potential for anti-inflammatory activity to be developed into a preparation that is a practical spray gel to use. The aim of this study is to made a spray gel containing ethanolic extract from the bulb of Eleutherine americana. Spray gel preparation was prepared by varying the concentration of Carbopol as a gelling agent with a concentration of F1 (0.4%), F2 (0.6%), and F3 (0.8%) with active substances and evaluated physical stability. Data from the results of physical stability testing in statistical analysis. Organoleptic test results and homogenity of ethanolic extract from the bulb of Eleutherine americana spray gel from all formulas showed stable, pH was in the range of 5.2-6.1 and Viscosity in formulas 1, 2, and 3 were respectively 0.65-1323 (Pa.s ) this condition is still within the range of viscosity of spray gel formulation, and have a spread pattern. While the formula 2 and 3, the viscosity is not eligible.
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Andong Merah terhadap Eschericia coli dan Staphylococcus aureus Reca Indiyen; Fika Aryati; Angga Cipta Narsa
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 11 (2020): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (442.396 KB) | DOI: 10.25026/mpc.v11i1.388

Abstract

Infection disease is one of the most common diseases in the world. Infection can be caused by bacteria Escherichia coli and Staphylococcus aureus which are now resistant to some antibiotics, so new agents are needed to overcome antibiotic resistance. Red andong leaves are empirically efficacious for treating wounds, hemorrhoids, inflammation, diarrhea and stopping bleeding (hemostasis). This study aims to determine the yield of ethanol extracts red andong leaves and determine the antibacterial activity of ethanol extracts of red andong leaves against Escherichia coli and Staphylococcus aureus. The research began with the process of extracting red andong leaves by maceration method, then carried out antibacterial testing by the well diffusion method. The results showed the extract concentrations of 10%, 30%, and 50% were able to inhibit the growth of Escherichia coli and Staphylococcus aureus. The biggest antibacterial activity of red andong extract was obtained at a concentration of 50% with a inhibition zone of 17,836 mm (Staphylococcus aureus) and 9,012 mm (Escherichia coli).
Co-Authors Angga Cipta Narsa Maulidya Maulidya Reca Indiyen Yurika Sastyarina