Garuda - Garba Rujukan Digital

Novita Eka Kartab Putri

Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Author-ID : 4295737

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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Uji Aktivitas Antibakteri Ekstrak Kombinasi Umbi Bawang Tiwai dan Kulit Buah Lemon Terhadap Pertumbuhan Staphylococcus aureus dan Escherichia coli: Antibacterial Activity Test of Combination of Tiwai Onion Bulbs and Lemon Peel on the Growth of Staphylococcus aureus and Escherichia coli Adinda Niti Meilaningrum; Novita Eka Kartab Putri; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Tiwai onion (Eleutherine americana (Aubl.) Merr) is a plant that contains several groups of secondary metabolites, one of which is the alkaloid group. Lemon rind (Citrus limon) is a plant that contains more than 2.5% essential oil and hesperidin. Several classes of secondary metabolite compounds from these two plants have antibacterial activity. This study aims to determine the characteristics of the extract and the antibacterial activity of the extract combination. The extract characteristics were tested in the form of organoleptic, pH and solubility. Meanwhile, the antibacterial activity test was carried out by using the well diffusion method. The results obtained were the characteristics of the tiwai bulb extract and lemon peel in the form of organoleptic (color: blackish red and yellow, thick texture, distinctive aroma of onion bulbs and lemon peel); pH (6.4 and 4.8); solubility (soluble in ethanol, methanol and aquades) and antibacterial activity at a concentration of 12: 3 with an average of 8.75mm (S. aureus) and 7mm (E.coli); 12: 6 with a mean of 11mm (S.aureus) and 7.25mm (E.coli); 12: 8 with an average of 12.25mm (S.aureus) and 13.75mm (E.coli). It can be concluded that at a concentration of 12: 8 the combination of these extracts had the highest average inhibition zone in inhibiting the two bacteria.

Uji Aktivitas Antibakteri Asap Cair Daun Mangga Kuweni (Mangifera odorata) terhadap Propionibacterium acnes: Antibacterial Activity Test of Liquid Smoked Leaves of Mango Kuweni (Mangifera odorata) against Propionibacterium acnes Bagaskara Adi Nugroho; Adam M. Ramadhan; Novita Eka Kartab Putri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Liquid smoke is the result of condensation or vapor condensation produced by direct or indirect combustion of materials containing cellulose, lignin, hemicellulose, and other carbon compounds. The function of liquid smoke is as an antioxidant and antibacterial. The purpose of this study was to determine the percent yield obtained, the secondary metabolites contained in the liquid smoke, and the bacterial inhibitory activity of the liquid smoke of the leaves of Mango Kuweni (Mangifera odorata). The method used in this research is pyrolysis and distillation for the manufacture of liquid smoke. As for the antibacterial test using the agar diffusion method with paper discs. The results showed that the yield obtained from the manufacture of liquid smoke grade 3 was 26.87%, grade 2 was 17.91%, and grade 1 was 14.33%. Secondary metabolites contained in the liquid smoke of the leaves of Mango Kuweni (Mangifera odorata) are Flavonoids, Alkaloids, and Phenols. The results of antibacterial testing using the bacteria Propionibacterium acnes showed inhibitory activity of 20% concentration of 4.4 mm (weak), 30% concentration of 4.76 mm (weak), 40% concentration of 5.21 mm (weak) and positive control, namely clindamycin of 15.27 mm (strong).

Optimasi Basis Formulasi Sediaan Handsanitizer Gel Ekstrak Daun Sirih Hitam (Piper betle var nigra) Sebagai Antibakteri: Optimization of the Hand Sanitizer Gel Preparation Base for Black Betel Leaf Extract (Piper betle var nigra) as an antibacterial Felina Alfiany; Novita Eka Kartab Putri; Fajar Prasetya
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Black betel leaf (Piper betle var. nigra) is one of the plants that has the potential as an antibacterial. This research is a laboratory experiment and aims to determine the optimum concentration of hand sanitizer gel base which will then be used in the formulation of hand sanitizer gel preparations with the active ingredient of black betel leaf. Optimization was carried out for 7 days by looking at the physical properties of the gel preparation, namely organoleptic, homogeneity, pH test, viscosity, and spreadability test. Handsanitizer gel was made in three formulas with three different concentrations of Carbopol 940, namely A, B, and C. The results obtained in the evaluation of the organoleptic test were observed in clear color, semisolid dosage form and smelled of Carbopol 940. Homogeneity test was indicated by the absence of granules. rough on the preparation. The pH test is the pH of the gel preparation which is stable at pH 7. The dispersion test of 5-7 cm shows a semisolid consistency which is very comfortable to use. The viscosity test showed that the gel viscosity was in the range of 1,206 cps - 1,820 cps. The results of the evaluation of the optimum hand sanitizer gel base are obtained if it has good physical quality and meets the criteria for gel preparation. Based on the evaluation results on the optimization of the hand sanitizer gel base, it was obtained that the Carbopol 940 gel base with a concentration of A had met the criteria for making gel preparations.

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