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Tjitjik Tjahjandarie
Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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Senyawa Alkaloid Furokuinolin dari Kulit Batang Zanthoxylum acanthopodium DC Tjitjik Tjahjandarie; Alfiah Nur Irza Gunawan; Ratih Dewi Saputri; Mulyadi Tanjung
Jurnal Sains dan Kesehatan Vol. 2 No. 2 (2019): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v2i2.121

Abstract

Dua senyawa alkaloid furokuinolin, diktammin (1) dan skimmianin (2) telah berhasil diisolasi dari kulit batang Zanthoxylum acanthopodium DC. Penentuan struktur kedua senyawa alkaloid ditetapkan berdasarkan analisis spektrum UV, IR, MS, 1D dan 2D NMR. Uji aktivitas antikanker senyawa 1–2 terhadap sel murine leukemia P-388 memperlihatkan nilai IC50 10,41 dan 4,85 µg/ml.
Co-Authors Alfiah Nur Irza Gunawan Mulyadi Tanjung Ratih Dewi Saputri