Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal Journal of Clinical Pharmacy and Pharmaceutical Science
Esti Mediastini
Unknown Affiliation
Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Perbandingan Konsentrasi HPMC Terhadap Stabilitas Fisik Sediaan Gel Ekstrak Etanol Daun Sirsak (Annona Muricata L.) Any Khoirotuzzahra; Fajaryanti, Nita; Esti Mediastini; Pitarisa, Agustina Putri
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 4 No. 1 (2025): April : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v2i1.13

Abstract

The soursop leaves (Annona muricata L.) are one of the plants containing acetogenins compounds and some alkaloids muricolin, cauxine, couclamine, stepharine and reticulin. These compounds are able to act as antibacterial causes of acne namely Propionibacterium acnes and Staphylococcus aureus. The extraction of soursop leaves is obtained by extracting the leaves of the shingle using the maseration method. The extract is formulated into a gel set with a difference in HPMC base concentration(Hydroxy Propyl Methyl Cellulose). The use of different HPMC concentrations aims to know the base concentration of HPMC there are differences or not in the gel ready ethanol extract of the shingle leaves. Physical stability testing conducted includes organoleptic, homogeneity, protection power, scatter power, lystuff, pH and viscosity with storage room temperature of 25ºC - 30ºC for 4 weeks. The results of the gel-ready physical stability study at room temperature storage of 25ºC - 30ºC for 4 weeks showed stable results for organoleptic testing, homogeneity, protection power, scattering power, pH and 2% thness at HPMC concentrations, while unstable results in viscosity tests.
Co-Authors Any Khoirotuzzahra Itsna Diah Kusumaningrum Kionowati Kionowati Marti Candrasari Melani Dewi Nita Fajaryanti, Nita Pitarisa, Agustina Putri Ria Septiyana Zakiyah Karim Amrillah