Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal Stannum : Jurnal Sains dan Terapan Kimia
Ary Samsiar
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Nanoemulsi Fraksi Daun Pelawan (Tristaniopsis merguensis Griff) Sebagai Antidiabetes Ary Samsiar; Robby Gus Mahardika; Occa Roanisca
Stannum : Jurnal Sains dan Terapan Kimia Vol 3 No 2 (2021): Oktober 2021
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v3i2.2290

Abstract

Diabetes mellitus is an increased level of sugar in the blood and the secretion of glucose in the urine due to metabolic disorders of insulin secretion. Efforts to treat diabetes mellitus can be done with therapy and drugs, but this can cause side effects. Diabetes can also be treated using herbal ingredients from nature. This study aims to determine the potential of pelawan leaves as an antidiabetic in the form of nanoemulsion.The pelawan leaves were extracted with acetone, then partitioned using MeOH solvent: water, again partitioned with ethyl acetate, then partitioned with n-hexane solvent. The nanoemulsion was prepared using a homogenizer at a stirring speed of 8000 rpm for 30 minutes with a composition of 2.5 ml VCO, 10 ml tween 80 and 37.5 ml water. Nanoemulsion from the MeOH: water and ethyl acetate fraction had better characteristics than the n-hexane fraction nanoemulsion. MeOH fraction nanoemulsion: water has a particle size of 123.8 nm, while ethyl acetate has a particle size of 153.9 nm. Meanwhile, the n-hexane nanoemulsion preparation had the characteristics of a larger particle size, namely 361 nm, and had a polydispersity index of 0.625 nm. The antidiabetic test using ethyl acetate fraction can inhibit α-glucosidase by 1.075% at a concentration of 2.5 mg / ml.
Co-Authors Roanisca, Occa Robby Gus Mahardika