Mohammad Eko Prayogo
Department Of Ophthalmology, Faculty Of Medicine, Public Health, And Nursing, Universitas Gadjah Mada/ Dr. Sardjito General Hospital, Yogyakarta, Indonesia

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Progression of myopia among medical students: A one-year cohort study Agung Nugroho; Mohammad Eko Prayogo; Widyandana Widyandana; Sagung Indrawati; Suhardjo Suhardjo
Journal of Community Empowerment for Health Vol 3, No 1 (2020)
Publisher : Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jcoemph.42887

Abstract

Myopia is a common refractive disorder in literate countries related to educationand higher occupational groups. External factors affecting myopia and its progression remainquestionable. Myopia onset and progression occur during childhood and teenager. This studyaimed to determine the progression of myopia and its associated factors in the medical studentof Faculty of Medicine UGM, Yogyakarta, Indonesia, through a one-year cohort study. An initialobservational and cross-sectional survey conducted as baseline data. Correlation calculatedusing Chi-square and the Spearman correlation coefficient analysis. A longitudinal cohortstudy conducted 12 months later to the initial survey. Myopia determined with an autorefractorwithout cycloplegia. BMI, intraocular pressure, and corneal curvature evaluated as factorsrelated to progression. Five hundred five students (98%; 505 of 515; 317 from the school ofmedicine (SoM), 188 from the school of nursing and nutrition (SoNN)) age 15-20 years wereexamined. Prevalence of myopia among SoM students was 69.4% (n=220 of 317) and 41.4%(n=78 of 188) in SoNN. Myopia (SER ≥-0.5 D) found in 298 students, 81 boys (27.2%) and 217girls (72.8%). Chi-square test revealed that myopia more common in Chinese than Javaneseand other (p=0.006) but a similar proportion in gender (p = 0.785) and age (p=0.369). Theaverage change of myopic progression was -0.401 D and -0.094 D per year in SoM and SoNN,respectively (p = 0.000). The average change of myopia of boys and girls was -0.138 D and-0.117 D, respectively (p = 0.871). There was no statistically significant correlation betweensubjective refraction change and factors related to progression. The progression of myopia inYogyakarta relatively similar to Western countries. Progression in the school of medicine washigher than the school of nursing and nutrition, but similar between boys and girls. No relatedfactor correlated with the progression of myopia expects further studies.
Retinal involvement of coronavirus disease (COVID-19): A systematic review Mohammad Eko Prayogo; Angela Nurini Agni
Journal of Community Empowerment for Health Vol 4, No 1 (2021): Special Issue of COVID-19
Publisher : Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jcoemph.61560

Abstract

COVID-19 has wide-ranging manifestations which involve various organs. Although COVID-19 is known to affect mainly the respiratory system, many patients suffered from ocular manifestations following SARS-CoV-2 infection, especially conjunctivitis. However, there was some evidence of broader ocular involvement, which could involve the retinal layer. This review aims to analyze the possible explanation of retinal involvement in COVID-19 and whether comorbidities increase the risk of retinal involvement in COVID-19. We conducted a systematic literature search during September 2020 using the PUBMED database and other additional sources (e.g., Google Scholar). There was no year of publication nor language restriction. Six papers are used in this literature review: two studies reported retinal lesions in COVID-19 patients, one study detected SARS-CoV-2 RNA in retinal biopsies and three studies proposed possible mechanisms of retinal involvement in COVID-19. Ocular structures express ACE-2, such as the aqueous humor, pigmented epithelium, and retina. This is supported by the finding of SARS-CoV-2 nucleic acid in postmortem patients. Retinal involvement in COVID-19 patients includes hyperreflective retina lesions, subtle cotton wool spots, and microhemorrhage. However, these findings do not necessarily indicate the specificity of retinal involvement. Diabetes mellitus may be associated with disease severity in patients with COVID-19. Some evidence of retinal involvement in SARS-CoV-2 infection involves the detection of retinal lesions, the expression of ACE-2 in the retina, and the role of comorbidities.
Kadar Plasma 25-Hydroxyvitamin-D (25-OHD) pada Pasien Age-related Macular Degeneration (AMD) Stadium Akhir di Yogyakarta: Studi Korelasi Supanji Supanji; Dewi Fathin Romdhoniyyah; Ayudha Bahana Ilham Perdamaian; Anindita Dianratri; Muhammad Bayu Sasongko; Angela Nurini Agni; Tri Wahyu Widayanti; Firman Setya Wardhana; Dian Caturini Sulistyaningrum; Mohammad Eko Prayogo; Masashi Kawaichi; Chio Oka
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 13, No 3, (2022)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol13.Iss3.art3

Abstract

Background: Age-related Macular Degeneration (AMD) is a degenerative disease caused by multiple factors, including inflammation. This condition may lead to irreversible macular damage. Vitamin D has anti-inflammatory and immune-modulating qualities, therefore, is expected to protect against the development of AMD.Objective: This study aimed to evaluate the correlation between plasma 25-hydroxyvitamin D (plasma 25-OHD) levels and neovascular Age-Related Macular Degeneration (nAMD).Methods: This was a case-control study involving AMD and control subjects. All subjects underwent a standardized eye examination to check for eligibility by a retinal specialist. Blood samples were drawn for analysis using a DRG Elisa Kit to determine the plasma 25-OHD (Total). Plasma 25-OHD levels were categorized into deficiency (<12 ng/mL), insufficiency (12 - <20 ng/mL), adequate (20 – 50 ng/mL), and high (>50 ng/mL).Results: Total subjects were 39, which consisted of 20 AMD subjects and 19 controls. There were 17 male subjects (43.6%) and 22 female subjects (56.4%). The mean age for the case and control group was 69.35±7.04 and 68.26±6.83, respectively (p=0.612). Those in their 70s dominated the age distribution with a percentage of 56.41% of all participants. The mean plasma 25-OHD in the case group was 32.30±17.10 ng/mL, while the control group was 50.63±11.95 ng/mL (p=0.066). There was no significant association between AMD and plasma 25-OHD levels in all groups (p>0.05).Conclusion: Plasma 25-OHD levels did not correlate positively with nAMD in our study population.
Appropriateness of Antibiotics Prescription for Conjunctivitis in Primary Health Care: A Literature Review: Oral Presentation - Observational Study - General practitioner Belinda Liliana; Atrika Fitri Nur Cahyani; Azura Nabila Putri; Oriana; Mohammad Eko Prayogo
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/ed988s41

Abstract

Abstract Introduction & Objectives : Conjunctivitis is one of the most common diseases present in primary health care (PHC) settings. The most common causes of conjunctivitis are viral infections and allergies. Despite this, patients diagnosed with conjunctivitis are often given antibiotics as therapy. Therefore, this literature review will assess the appropriateness of antibiotics prescription for patients with conjunctivitis in PHC settings. Methods : The authors performed an electronic literature search on databases PubMed and Scopus for eligible articles, which showed antibiotic prescription for patients with conjunctivitis in PHC settings and published between 2012 and 2022, then further sorted based on the inclusion and exclusion criteria. Results : A total of 8 studies met the inclusion criteria. Five studies showed high rates of inappropriate antibiotic prescriptions for patients with conjunctivitis in PHC. Several factors that might cause inappropriate prescription include the difficulty in determining the exact etiology, the need to fulfill patients’ satisfaction, the amount of experience and training doctors have received, consultation’s duration, stigma, the socio-demographic factors of the patient, the availability of treatment guidelines, and the availability of drugs. Some of the consequences that are concerned include the rise of antimicrobial resistance, stigma revolving around the usage of antibiotics for every infectious disease, and economic burden. Delays in prescribing antibiotics and proper training for general practitioners can be a solution to reduce inappropriate prescribing of antibiotics. Conclusion : Prescribing antibiotics for patients with conjunctivitis in PHC settings is mostly inappropriate