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Pengaruh Vitamin D3 Terhadap Kadar Hemoglobin Tikus Wistar yang Dipapar Asap Rokok Hetti Rusmini; Dita Fitriani; Dessy Hermawan; Diah Adelia Emilda
ARTERI : Jurnal Ilmu Kesehatan Vol 1 No 1 (2019): November
Publisher : Puslitbang Sinergis Asa Professional

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (456.211 KB) | DOI: 10.37148/arteri.v1i1.13

Abstract

Hemoglobin is a tetrametric erythrocyte protein that carries O2 to the tissues and returns CO2 and protons to the lungs. Cigarette smoke is proven that could reduce hemoglobin levels through oxidative stress which causes the erythrocyte membrane to be easily lysed. The lysis erythrocyte membrane causes hemoglobin levels to be low. Vitamin D is included in natural antioxidants which have a neuroprotective tendency through antioxidative mechanisms. To determine the effect of giving vitamin D3 on hemoglobin levels in white rats (Rattus norvegicus) male Wistar strain after being exposed by cigarette smoke. This type of pure experimental research (tue-experiment) used pre and post with control group design. Samples were white rats (Rattus norvegicus) male Wistar strain aged 10-12 weeks with the weight of around 150-200 grams in a total of 24 individuals. Samples were divided into four groups including K1 which is not exposed by cigarette smoke and not given of vitamin D3, K2 is a group exposed by cigarette smoke but not given of vitamin D3, K3 is a group that is not exposed by cigarette smoke but given of vitamin D3 a dose of 0.2 µgr /head, P1 is a group exposed by cigarette smoke and given a vitamin D3 dose of 0.2 µgr /head. The test of paired t-test showed a significant difference p <0.05 in the K2 group with p = 0.044, the K3 group with p = 0.013, and P1 group with p = 0.037. Whereas in group 1 there was no significant difference p = 0.932. The One-way Anova test obtained results with a value of p = 0.027 (p <0.05) which means that there were significant differences between groups. The Post Hoc LSD test showed a significant difference in group 1 whit group 2 p = 0.025 and in group 2 with group 3 p = 0.012.
Analisis Faktor Risiko Hipertensi Di Wilayah Provinsi Lampung (Analisis Data Riskesdas 2018) Diah Adelia Emilda; Achmad Farich; Agung Aji Perdana; Fitri Ekasari; Khoidar Amirus
Jurnal Penelitian Pendidikan IPA Vol. 9 No. 11 (2023): November
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i11.3782

Abstract

Hypertension is systolic blood pressure ≥ 140, and diastolic ≥ 90 mmHg (Unger et al., 2020). Indonesia showed an increase from the 2013 Riskesdas data (25.8%) and 2018 Riskesdas (34.11%). Lampung ranks 16th with the highest number of hypertension in Indonesia with a presentation reaching 29.94% (Kemenkes RI, 2019) and (Kementrian Kesehatan Republik Indonesia, 2018). This research aims to determine the risk factors for hypertension in the Lampung province community using 2018 Riskesdas data. Using secondary data with a quantitative research type and cross-sectional design. The research population was the total sample of the 2018 Riskesdas in Lampung Province, namely 22,345 individuals, and the sample excluding pregnant data and incomplete data resulted in a sample of 11,095 individuals. Data analysis used univariate, chi-square, and multiple logistic regression. Bivariate test results of gender, age, education, diabetes mellitus, salty consumption, smoking, physical activity, obesity p-value α<0.05 means there is a significant relationship between gender, age, education, diabetes mellitus, salty consumption, smoking, physical activity, obesity on the incidence of hypertension in Lampung Province. Obesity has a modifying effect on the relationship between age and the incidence of hypertension, in obese people aged ≥45 the risk of experiencing hypertension is 3,804 times higher than those aged <45 years after controlling for gender, education, history of diabetes mellitus, salt consumption, smoking, and physical activity.
Analisis Faktor Risiko Hipertensi Di Wilayah Provinsi Lampung (Analisis Data Riskesdas 2018) Diah Adelia Emilda; Achmad Farich; Agung Aji Perdana; Fitri Ekasari; Khoidar Amirus
Jurnal Penelitian Pendidikan IPA Vol 9 No 11 (2023): November
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i11.3782

Abstract

Hypertension is systolic blood pressure ≥ 140, and diastolic ≥ 90 mmHg (Unger et al., 2020). Indonesia showed an increase from the 2013 Riskesdas data (25.8%) and 2018 Riskesdas (34.11%). Lampung ranks 16th with the highest number of hypertension in Indonesia with a presentation reaching 29.94% (Kemenkes RI, 2019) and (Kementrian Kesehatan Republik Indonesia, 2018). This research aims to determine the risk factors for hypertension in the Lampung province community using 2018 Riskesdas data. Using secondary data with a quantitative research type and cross-sectional design. The research population was the total sample of the 2018 Riskesdas in Lampung Province, namely 22,345 individuals, and the sample excluding pregnant data and incomplete data resulted in a sample of 11,095 individuals. Data analysis used univariate, chi-square, and multiple logistic regression. Bivariate test results of gender, age, education, diabetes mellitus, salty consumption, smoking, physical activity, obesity p-value α<0.05 means there is a significant relationship between gender, age, education, diabetes mellitus, salty consumption, smoking, physical activity, obesity on the incidence of hypertension in Lampung Province. Obesity has a modifying effect on the relationship between age and the incidence of hypertension, in obese people aged ≥45 the risk of experiencing hypertension is 3,804 times higher than those aged <45 years after controlling for gender, education, history of diabetes mellitus, salt consumption, smoking, and physical activity.