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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy)
Ulya Felasufah
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Medicine & Pharmacology

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AKTIVITAS ANTIJAMUR KRIM EKSTRAK ETANOL DAUN JAMBU MONYET (Anacardium occidentale L.) DAN KULIT BATANG RAMBUTAN (Nephelium lappaceum) TERHADAP Candida albicans Devi Nisa Hidayati; Ulya Felasufah; Amaliyah Ayu Nurfitriani; Mufrod Mufrod
Jurnal Ilmu Farmasi dan Farmasi Klinik Jurnal Ilmu Farmasi & Farmasi Klinik Vol 14 No 2 Desember 2017
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (322.849 KB) | DOI: 10.31942/jiffk.v14i2.2063

Abstract

ABSTRACT Ethanol extract of Anacardium occidentale and rambutan bark  (Nephelium lappaceum) proved to have antifungal activity agains Candida albicans. Efforts to improve comfort and ease of use then made in the form of cream formulation.The aim of study is to know the antifungal activity of cream with various concentration of  Anacardium occidentaleleaf extract and rambutan bark againstCandida albicans. Extraction of ethanol extractAnacardium occidentale leaf (EAOL) and  rambutan bark (ERB) used maceration method. Solvents used ethanol 70% and ethanol 96%, respectively. Formulation cream of EAOL and ERB was maked 3 formulation.  Formulation cream EAOL with concentration of variations extract are FI (10,5%), FII (12,5%), FIII (14,5%). Formulation cream ERB with concentration of varions extract  are FI (10%), FII (15%), FIII (20%).  Antifungal activity was determined in the cream using agar diffusion method and  zone of inhibitionwere analyzed using descriptive. The results showed that  antifungal activity against  Candida albicans  of cream EAOL concentration 14,5% with zone of inhibition is 7,16 ± 0,28 mm and cream ERB concentration 20% with zone of inhibition is 9,5 ± 0,5 mm.  Kata Kunci : Antifungal,  Anacardium occidentale, Nephelium lappaceum,  Formulation ofcream
Co-Authors Amaliyah Ayu Nurfitriani Devi Nisa Hidayati Mufrod Mufrod