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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Journal of Innovative and Creativity
Layyinatul Fuadah
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Education Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Social Sciences Other

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EFEK ANTIDIARE EKSTRAK ETANOL DAUN PARIJOTO (Medinilla speciosa Blume) PADA MENCIT JANTAN GALUR BALB/C Yance Anas; Desi Rakhmawati; Layyinatul Fuadah; Nola Carina Rahayu
Jurnal Ilmu Farmasi dan Farmasi Klinik Jurnal Ilmu Farmasi & farmasi Klinik Vol 16 No 1 Juni 2019
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (537.364 KB) | DOI: 10.31942/jiffk.v16i01.2926

Abstract

ABSTRACTParijoto is one of a rare plant species in Indonesia, and its leaves have traditionally been utilized to treat diarrhea in the area of Kudus Regency, Indonesia. Parijoto leaves contain active compounds of tannin and flavonoid which have antidiarrheal properties. This investigation intends to demonstrate the antidiarrheal effect of parijoto leaf ethanol extract (EEDP) on male Balb/C mice castor oil-induced diarrheal and reveal its antidiarrheal mechanism through antimotility and antisecretory testing. EEDP made by maceration method. The antidiarrheal effects of three series level EEDP (500; 1,000 and 2,000) mg / Kg BB tested on diarrhea mice induced by castor oil. Concurrently, the antimotility and antisecretory effects of EEDP investigated with the intestinal transit method and castor oil-induced enteropooling. The data in this study were the onset of diarrhea, the weight of liquid-formless stools (for 8 hours), the ratio of digestion tracts passed by norit markers, and the volume of intestinal contents. These data were analyzed statistically at the 95% confidence level. The examination presumed that EEDP was able to respite the onset of diarrhea and diminish the formation of liquid-formless feces in male Balb/C mice induced by castor oil. The antidiarrheal mechanism of EEDP also exhibited in this study through its effects as antimotility and antisecretory.Keywords: Parijoto leaf ethanol extract, antidiarrheal, antimotility, antisecretory
Association Between Reproductive Health Knowledge and Menarche Preparedness Among Elementary School Girls in Bogor Regency, Indonesia Masluroh; Layyinatul Fuadah; Yuyun Sunarsih; Mega Aprilia; Lusiana Novita; Asih Handayani; Kusnanto
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.9070

Abstract

Menarche marks an essential stage in female reproductive maturity. However, many young girls lack adequate knowledge and emotional preparedness, which may lead to anxiety, confusion, and negative attitudes toward menstruation. This study aimed to analyze the relationship between reproductive health knowledge and menarche preparedness among elementary school girls in Bogor Regency, Indonesia. A cross-sectional study was conducted among 72 fifth- and sixth-grade students at SDN Sukamaju 01 Jonggol, Bogor Regency. Total sampling was employed, and data were collected using a validated and reliable questionnaire (Cronbach’s α = 0.82). Descriptive statistics and Spearman’s rank correlation test were used to examine the association between knowledge and readiness, with a 95% confidence level. The mean age of participants was 11.2 ± 0.7 years. Most respondents demonstrated high reproductive health knowledge (59.7%), while 92% were categorized as unprepared for menarche. The Spearman correlation test revealed no significant association between knowledge and preparedness (rₛ = 0.011, p = 0.924). Although students’ knowledge of reproductive health was generally high, emotional and practical readiness for menarche remained low. These findings indicate that increasing knowledge alone is insufficient to ensure preparedness. Comprehensive, school-based reproductive health education programs that integrate cognitive, affective, and psychomotor aspects—along with parental involvement—are strongly recommended.
Co-Authors Asih Handayani Desi Rakhmawati Kusnanto Lusiana Novita Masluroh Mega Aprilia Nola Carina Rahayu Yance Anas Yuyun Sunarsih