Article Per Year (5 Year)
p-Index From 2020 - 2025
0.817
P-Index
This Author published in this journals
All Journal Tirtayasa Medical Journal Bioma : Jurnal Ilmiah Biologi JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia
Desak Gede Budi Krisnamurti
Department Of Medical Pharmacy, Faculty Of Medicine Universitas Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Hubungan antara Kecerdasan Emosional dengan Efektivitas Diskusi PBL secara Online Mahasiswa Kedokteran FKIK Untirta Trisnasari, Erni; Krisnamurti, Desak Gede Budi; Nugraha, Ummu Zakiyatun Nisa
Tirtayasa Medical Journal Vol 3, No 2 (2024): May
Publisher : Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/tmj.v3i2.25478

Abstract

Lack of learning motivation in discussion group members will cause students to contribute only little and less actively during discussion. Given the importance of group discussion learning method (PBL) in achieving medical learning CPL, the author is interested in conducting research into the relationship between emotional intelligence and the effectiveness of group discussions online in FKIK Untirta medical students. Research design method using cross sectional design, quantitative observational research. The researchers used a stratified random sampling technique on a medical student. The reseach uses two types of questionnaires; the adoption questionnaire of the Emotional Competence Inventory of Ini Kadek’s research, and the Tutorial Group Effectiveness Instrument (TGEI). Based on the results of the study, the majority of emotional intelligence were in the middle category with 50 respondents (53,2%), in the high category 44 respondents (46,8%), and no respondents in the low emotional intelligence category. PBL discussions conducted by medical students of FKIK Untirta have been conducted effectively (98,9%). Bivariate analysis using Fisher Exact Test, showed no relationship (p>0,05) between emotional intelligence and discussion effectiveness. The category of emotional intelligence in students is at a moderate leel, the PBL discussions are already running effectively. There was no relationship between emotional intelligence and effectiveness of PBL discussions.
T HELPER 17 (Th17) AND REGULATORY T (Treg) CELLS PROFILE IN TYPE-2 DIABETES MELLITUS (T2DM) DWIKARJANTI, INDRANITA; KRISNAMURTI, DESAK GEDE BUDI; KODARIAH, RIA
BIOMA : Jurnal Ilmiah Biologi Vol. 14 No. 1 (2025): April 2025
Publisher : LPPM Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/bioma.v14i1.1208

Abstract

One of metabolic disorder disease is Type 2 Diabetes mellitus (DM), leading to increased glucose, cholesterol, and lipid levels in the blood. Type 2 DM results in insulin resistance within the body. Glycolysis, oxidative phosphorylation, and fatty acid are the three main metabolic pathways which provide energy for T cells. T cells will ploriferate, differentiate and become active into T Helper-17 and T regulator (Treg) cells because of these pathways. The profile of TH-17 cells and Treg cells in type 2 diabetes will be opposite in terms of the number of their populations caused by metabolic disorders in the body. Type 2 diabetes make an immunology response with increasingly number of TH-17 cells, while lack of Treg cells. Many studies have shown that diabetes mellitus as a metabolic disease effect populations of T Helper-17 and regulatory T cells. Glycolysis is the main energy metabolism becomes important factor that stimulate the proliferation and differentiation of Th-17 cells. The energy produced from this metabolism is in the form of ATP, which is the result of glucose synthesis using the Glucose transporter (GLUT). Glucose transporters (GLUT-1) are most dominantly expressed by Th-17 cells and Treg cells. Metabolic disorder causes an imbalance in the population of TH-17 cells with Treg cells. This review will explain the profiles of TH-17 and regulatory T cells in Diabetes mellitus and their relationship with body metabolism disease.
Chelating Effect of Water Extract of Mangifera foetida L. Leaf in Serum of Thalassemia Patient by Ex Vivo Test Dessy Framita Sari; Erni Hernawati Purwaningsih; Desak Gede Budi Krisnamurti
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 1 No 2 (2012): JIMKI : Jurnal Ilmiah Mahasiswa Kedokteran Indonesia
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Thalassemia is a genetic disorder, which is caused by the diminshed synthesis of globin polypeptide chains. In Indonesia, 3-5% of cases are beta-thalassemia and 2.6 to 11% are alpha-thalassemia. Regular blood transfusion is neede but iron overload is the consequence. That's why Deferoxamine is used as a chelating agent which function is bind iron and excrete them. Unfortunately, Deferoxamine needs high cost with high side effects. Therefore, an alternative natural medicine is required, that is mangiferin derived from aqueous extract of Mangifera foetida L. leaf. The aim of this research is to utilize the natural substance as a chelating agent of feritin in thalassemia patient's serum. This was an experimental study, which used serum of patient with thalassemia. One Way ANOVA statistical test proved that the aqueous ectract of Mangifera foetida L. dose of 0.375 mg and 0.75 mg has a chelating effect compared with negative control (p=0.005). However, when subsequently tested with post hoc, 0.375 mg extract doesn't show a chelating effect compared with mangiferin (p=0.018). In the other hand, 0.75 mg extract has shown a chelating effect but not as good as mangiferin (p=0.259). It is consiered that the low doses of extract and a possibility that the extract doesn't bind the iron directly are the facttors which influence the result. That's why manfigerin still has better effectiveness in binding iron compared with aqueous extract of Mangifera foetida L. leaf dose of 0.375 mg and 0.75 mg.
Co-Authors Ani Retno Prijanti Dalilati, Annia Zhafarina Dessy Framita Sari DWIKARJANTI, INDRANITA Erni Hernawati Purwaningsih, Erni Hernawati Nugraha, Ummu Zakiyatun Nisa Ria Kodariah Trisnasari, Erni