Ita Muharram Sari
National Brain Center Hospital Prof. Dr. dr. Mahar Mardjono, Jakarta, Indonesia

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

Role of Procalcitonin in Intracerebral Hemorrhage Stroke with COVID-19 Ita Muharram Sari; Iswandi Erwin; Fiizhda Baqarizky; Puspa Oktaviani; Sardiana Salam; Anna Mardiana Ritonga
AKSONA Vol. 2 No. 1 (2022): JANUARY 2022
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (288.835 KB) | DOI: 10.20473/aksona.v2i1.219

Abstract

Introduction: As COVID-19 has rapidly spread worldwide, it is an urgent health problem. Some evidence suggests that SARS-CoV-2 also affects the central nervous system. Stroke is the most common disease of the central nervous system. In contrast to ischemic stroke, which can occur due to the hypercoagulation effect of COVID-19, the study of Intracerebral Hemorrhage (ICH) associated with COVID-19 is still unclear. Objective: This paper investigated the characteristics of an inflammatory biomarker and compared the outcomes of ICH patients with COVID-19 and ICH patients without COVID-19. Methods: We conducted a retrospective, observational analysis case-control of patients (n = 42) admitted with ICH with positive COVID-19 and ICH with negative COVID-19 at the National Brain Center Hospital Prof.Dr.dr. Mahar Mardjono from March 2020 to August 2021. We took blood samples and COVID-19 swab PCR on the first day of admission, and GOS was measured when the patients were discharged. Results: There were 21 ICH patients with positive COVID-19 who had a significantly procalcitonin (p < 0.05) compared  to control patients. From Spearman’s correlational analysis, there is a significant value between early procalcitonin and the Barthel Index (rs = -0,374, p < 0.05), early CRP and GOS (rs =- 0.329, p < 0.05), which indicates weak-inverse correlation, and between early PCT and GOS (rs = -0.438, p < 0.05) which indicates moderate-inverse correlation. Conclusion: The level of procalcitonin was increased in ICH patients with COVID-19. Maybe PCT could be a predictor of outcome in ICH patients with COVID-19.
Comparison of Oxygen Saturation Dynamics Between Types of Acute Stroke in Early Hospitalization Period Naura Waliya Maharani; Ita Muharram Sari; Patwa Amani
Biomedical Journal of Indonesia Vol. 10 No. 1 (2024): Vol 10, No 1, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i1.181

Abstract

Introduction. Stroke is the number one cause of death and disability in Indonesia. It was found that the incidents of stroke were higher at ages over 45 years. The use of pulse oximeter is an efficient step in monitoring oxygenation in stroke patients. Decreased oxygen levels can cause neurological deficits such as cognitive impairment, causing patients to have problems in attention and executive functions. This study aims to determine the relationship between the type of acute stroke and oxygen saturation in early hospitalization period. Methods. This research was carried out from November to December 2023 at the National Brain Center Hospital, Jakarta, using a cross sectional approach. Information on diagnosis and oxygen saturation values were obtained through medical records, with a total of 70 patients as subjects. Subjects selected through simple random sampling with patients age over 45 years. Statistical analysis used the Mann Whitney test with a significantly different p value <0.05. Results. A total of 68.6% of the subjects were male with ages of 45-59 dominated the subjects at 51.4%. Statistical tests on the type of acute stroke with oxygen saturation values produced a value of p = 0.044 (p < 0.05) on the 3rd day of hospitalization. These results indicate a significant relationship between the type of acute stroke and the oxygen saturation value on the 3rd day of hospitalization. Conclusion. There is a significant correlation between the type of acute stroke and oxygen saturation in the 3rd day of hospitalization.