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All Journal Program Kreativitas Mahasiswa - Pengabdian Kepada Masyarakat JFIOnline
Desy Fatmawati
Universitas Airlangga, Surabaya
Education Health Professions Medicine & Pharmacology

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PENINGKATAN KUALITAS HIDUP PASIEN KANKER RUMAH SINGGAH MELALUI PENDAMPINGAN KELUARGA PASIEN DI YAYASAN KANKER INDONESIA (YKI) CABANG JAWA TIMUR Fajariah, Isnaini; Fatmawati, Desy; Wahyuningtyas, Ellen; Reza, Chaerul
Program Kreativitas Mahasiswa - Pengabdian Kepada Masyarakat PKM-M 2013
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Indonesian Cancer Foundation (YKI) is a nonprofit organization that has the sole purpose of social and humanitarian field, especially in the fight against cancer that already have networks across the province in Indonesia. Halfway house is a place reserved for cancer patients who are undergoing outpatient care to facilitate the patient to reach the hospital patients who were referred for treatment. With the alternative activities that are beneficial to patients and their families, we propose a program " Improving the Quality of Life Patient Assistance Family Shelter Home through the Indonesian Cancer Foundation Patient In East Java branch ", with several objectives, namely to make cancer patients and families are always optimistic so motivated to improve their health status. Making cancer patients and families to be more productive despite the limitations physical condition. To change the behavior of the cancer patient and family so that they can always make up a healthy lifestyle. Also in this program is done by means of the method of implementation approaches, make a visit to the Indonesian Cancer Foundation to determine the condition and patient activity. Cooperation with related parties. Implementation of the program in accordance with the plans and design of program activities improved quality of life of cancer patients. Evaluation of the program and the possibility of improving the quality of the program ( program sustainability ).
Efektivitas Enhancer Natrium Lauril Sulfat Dalam Patch Topikal Antiinflamasi Ekstrak Etanol Kencur (Kaemferia Galanga L.) Terhadap Jumlah Neutrofil dan Makrofag Pada Mencit Fatmawati, Desy; Dermayati, Cyntia Zain; Hamid, Iwan Sahrial; Hendriati, Lucia
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 8, No 2 (2016)
Publisher : Indonesian Research Gateway

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Abstract

Ethanol extract Kencur (Kaempferia galanga L.) has been proven to have antiinflammatory effect as well as to decrease the side effect of NSAIDs drug use, to develop the formulation of ethanol extract of kencur, then made in the dosage form of topical patch. Topical patch preparations are expected to avoid effects on the gastrointestinal tract, first- pass metabolism, and facilitate the use of the patient thereby increasing patient compliance. In the patch formulation, the most important things to note is the penetration enhancer/ enhancer, and enhancer used in this study is sodium lauryl sulphate. This study aims to determine the effectiveness of sodium lauryl sulphate in the preparation of a topical patch of kencur extract as anti inflammatory on the number of neutrophils in the blood. The research method uses canrrageenan as an inflammation inductor and neutrophil count observation was conducted using blood smears, then was observed on the first, third and seventh. Group of treatment which was given sodium diclofenac gel as positive control, group of treatment which was without enhancer as the 1st group, groups of treatment which were givenenhancer 1%, 3%, and 5% as the 2nd, 3rd and 4th group. The result was analyzed by one way ANOVA, followed by Post Hoc Duncan. The experimental results prove that there was a significant difference between the number of neutrophils and macrophages in the negative control group who were not given enhancer and the treatment group were given enhancer sodium lauryl sulphate values ( p < 0.05 ). As well as the group treated with the addition of enhancer sodium lauryl sulfate showed a greater amount of decline compared to the treatment group that contains only ethanol extract kencur.
Efektivitas Enhancer Natrium Lauril Sulfat Dalam Patch Topikal Antiinflamasi Ekstrak Etanol Kencur (Kaemferia Galanga L.) Terhadap Jumlah Neutrofil dan Makrofag Pada Mencit Fatmawati, Desy; Dermayati, Cyntia Zain; Hamid, Iwan Sahrial; Hendriati, Lucia
Jurnal Farmasi Indonesia Vol 8, No 2 (2016)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1970.423 KB) | DOI: 10.35617/jfi.v8i2.517

Abstract

Ethanol extract Kencur (Kaempferia galanga L.) has been proven to have antiinflammatory effect as well as to decrease the side effect of NSAIDs drug use, to develop the formulation of ethanol extract of kencur, then made in the dosage form of topical patch. Topical patch preparations are expected to avoid effects on the gastrointestinal tract, first- pass metabolism, and facilitate the use of the patient thereby increasing patient compliance. In the patch formulation, the most important things to note is the penetration enhancer/ enhancer, and enhancer used in this study is sodium lauryl sulphate. This study aims to determine the effectiveness of sodium lauryl sulphate in the preparation of a topical patch of kencur extract as anti inflammatory on the number of neutrophils in the blood. The research method uses canrrageenan as an inflammation inductor and neutrophil count observation was conducted using blood smears, then was observed on the first, third and seventh. Group of treatment which was given sodium diclofenac gel as positive control, group of treatment which was without enhancer as the 1st group, groups of treatment which were givenenhancer 1%, 3%, and 5% as the 2nd, 3rd and 4th group. The result was analyzed by one way ANOVA, followed by Post Hoc Duncan. The experimental results prove that there was a significant difference between the number of neutrophils and macrophages in the negative control group who were not given enhancer and the treatment group were given enhancer sodium lauryl sulphate values ( p < 0.05 ). As well as the group treated with the addition of enhancer sodium lauryl sulfate showed a greater amount of decline compared to the treatment group that contains only ethanol extract kencur.
Co-Authors Chaerul Reza Dermayati, Cyntia Zain Dermayati, Cyntia Zain Ellen Wahyuningtyas Isnaini Fajariah Iwan Sahrial Hamid Lucia Hendriati