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All Journal METAMORFOSA Journal of Biological Sciences Jurnal Farmasi Higea
Amri Bakhtiar
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Immunology & microbiology Medicine & Pharmacology

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Pengendalian Staphylococcus Aureus Dan Methicillin Resistant Staphylococcus Aureus Menggunakan Ramuan Obat Diare Masyarakat Maek Muthia Miranda Zaunit; Fuji Astuti Febria; Amri Bakhtiar
Metamorfosa: Journal of Biological Sciences Vol 6 No 1 (2019)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2019.v06.i01.p03

Abstract

The aims of this research are to analyze the phytochemical contents and to know the antibacterial potential of medicines herbs of Maek Society in controlling S. aureus and Methicillin Resistant Staphylococcus aureus (MRSA). This research is conducted on March – July 2017 in Biota Sumatera Laboratory and Microbiology Research Laboratory of Biology Departement, Andalas University. The method is experiment with five treatments of concentration against two bacterias test. The result showed that phytochemical test of medicine herbs extract contains alcaloids and phenol. All of the extracts concentration able to control S. aureus and MRSA. Antibacteria activity of the medicine herbs against S. aureus is stronger than againts MRSA. The highest diameter of the inhibitory zones extract against S. aureus is 12,98 ± 1,29 mm and against MRSA is 12,56 ± 0,38 mm. Key words: Staphylococcus aureus, MRSA, medicine herbs, phytocemical test, antibacteria
Potensi Pakih Sipasan (Blechnum orientale) sebagai Antibakteri Terhadap Staphylococcus aureus dan Methicillin Resistant Staphylococcus aureus Yossi Rahmadeni; Fuji Astuti Febria; Amri Bakhtiar
Metamorfosa: Journal of Biological Sciences Vol 6 No 2 (2019)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2019.v06.i02.p12

Abstract

Staphylococcus aureus is an opportunistic pathogenic bacteria. These bacteria can cause infections of the skin, bones, lungs, heart or systemic infections. Giving antibiotics does not fit the recommendations result in the emergence of resistant strains. Methicillin Resistant Staphylococcus aureus (MRSA) is one of the bacteria beta-lactam antibiotic resistant. Pakih Sipasan (Blechnum orientale) is a low level plants that is widely used Simanau villagers at Solok District in overcoming skin infections. The aims of this research are to determine the phytochemical content of B. orientale and to know antibacterial potential against S. aureus and MRSA. This research was conducted in March-July 2017 at Biota Laboratory of Sumatera and Microbiology Research Laboratory of Biology Department, Andalas University. Research method is experiment. The extracts were prepared with concentrations of 20 mg/ml, 40 mg/ml, 60 mg/ml, 80 mg/ml and 100 mg/ml. The data obtained are analyzed and presented in the form of tables and drawings are presented descriptively. The results showed that the B. orientale contain chemical compounds class of alkaloids, phenols and flavonoids. All treatments have potential as antibacterial to S. aureus and MRSA. The antibacterial activity of the B. orientale against S. aureus is stronger than against MRSA. The average diameter of inhibitory zone formed from concentrations of 20 mg/ml to 100 mg/ml of S. aureus ranged from 13.00 mm - 14.95 mm and to against MRSA between 11.31 mm - 14.48 mm. Key words: Staphylococcus aureus, MRSA, phytocemical test, antibacteria, Blechnum orientale
Optimasi Pengolahan Gambir Dengan Kempa Hidraulik Dan Kempa Ulir Hendri Satria Kamal Uyun; Deddi Prima Putra; Amri Bakhtiar
Jurnal Farmasi Higea Vol 13, No 1 (2021)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52689/higea.v13i1.392

Abstract

Gambir merupakan ekstrak daun dan ranting tanaman Uncaria gambir (Hunter) Roxb yang diolah dengan cara perebusan, pengempaan, penirisan pencetakan dan pengeringan. Tujuan penelitian adalah mengamati pengaruh kempa hidrolik dan kempa ulir pada proses pengolahan gambir dengan atau tanpa perajangan. Setiap metode dilakukan dua kali pengempaan. Analisis mutu berdasarkan SNI 01-3391-2000. Hasil penelitian menunjukkan rendemen gambir yang paling tinggi diperoleh dengan cara kempa ulir dengan perajangan yaitu (5,57 % ± 0,60) diikuti secara berturut turut kempa ulir tanpa perajangan  (4,37% ±0,78), kempa hidraulik dengan perajagan (3,56% ± 0,26) dan kempa hidraulik tanpa perajangan (3,08% ± 0,23). Rendemen gambir yang diperoleh pada kempa kedua ulir tanpa perajangan dan tanpa perajangan menunjukkan hasil yang sama (0,9% ± 0,32 dan 0,9% ± 0,19) yang diikuti  kempa hidraulik dengan perajagan (0,66% ± 0.09) dan kempa hidraulik tanpa perajangan (0,55%  ±0,20). Gambir yang diolah dengan kempa hidraulik dan kempa ulir pada kempa pertama baik yang tidak dirajang maupun dirajang demikian pula halnya dengan gambir yang diolah dengan kempa Hidraulik  kempa kedua baik yang tidak rajang maupun dirajang memenuhi standar SNI untuk mutu 1. Sedangkan gambir yang diolah dengan kempa ulir kempa kedua baik tidak dirajang maupun dirajang tidak memenuhi persyaratan SNI untuk mutu 1 maupun mutu 2.
Co-Authors Deddi Prima Putra Fuji Astuti Febria Kamal Uyun, Hendri Satria Yossi Rahmadeni Zaunit, Muthia Miranda