Titi Sumanti
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UJI PREKLINIS VIRGIN COCONUT OIL TERHADAP PENINGKATAN KADAR KOLESTEROL BAIK HDL, PENURUNAN KADAR TRIGLISERIDA, PROFIL KIMIA ASAM LEMAK (C6-C18) DAN OMEGA-3 PADA SERUM DARAH TIKUS PUTIH (Mus musculus) Sumaryati Syukur; Rina Dahlyanti; Titi Sumanti; Yulia Murni; Zoni Hidayat; Helmi Arifin; Endang Purwati; Risfaheri -
Jurnal Riset Kimia Vol. 1 No. 1 (2007): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v1i1.79

Abstract

 ABSTRACT The Virgin Coconut Oil (VCO) products have different qualities and controversy effects of lipids metabolism. This research has been used one of VCO product that was produced by fermentation method using Lactobacillus sp. It has high amount of lauric acid (C12) up to 51 %, caprilic acid (C8) 8.9 %, capric acid (C10) 7 % include Omega-3, 6 and 9, vitamins A, D, E, K and three kinds of phytohormone. The ratio of Omega-3 and 6 was very proportional, therefore it is important to investigate the Pre Clinic Test of animal experiment. Pre Clinic Test of dietary VCO as food supplement has been determined by using 40 mice’s, which divided into 4 groups. Feeding on egg yolk to Group I (negative control), Group II (positive control) increased cholesterol level. The others were Group III (egg yolk and VCO 2 %) and group IV (egg yolk and VCO 4 %). It was determined the total of cholesterol, HDL at 10th, 20th and 30th day treated by using the enzymatic methods. The dietary of VCO 2-4 % resulted in significant increases in HDL levels from 32 % to 69 %. The dietary of VCO 4 % for four weeks did not toxic to mice metabolism. Triglycerides level decreased 50 % from 177 to 85 and similar resulted to cholesterol ratio. Feeding on VCO for 4 weeks, the SCFA and MCFA not detected in serum of mice. The LCFA (C16) palmitate in significant decreased from 0.96 to 0.1%. The significant level of Omega-3 increased more than three times in serum of mice dietary VCO 2-4 %.  Keywords: Coconut Oil, Lactobacillus
PBL-Based Online Worksheet on Green Chemistry to Enhance Students’ Literacy and Numeracy Skills Sumanti, Titi; Gani, Abdul; Yusrizal, Yusrizal; Khaldun, Ibnu; Winarni, Sri; Nabilah, Putri
Jurnal Pemberdayaan Masyarakat Vol 4, No 2 (2025)
Publisher : Yayasan Keluarga Guru Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46843/jpm.v4i2.487

Abstract

The limited availability of digital learning tools that effectively integrate green chemistry concepts while enhancing scientific literacy and numeracy presents a challenge in science education. Chemistry learning that integrates environmental issues, particularly the concept of green chemistry, requires contextual and innovative teaching materials to support the enhancement of students' scientific literacy and numeracy skills. This study aimed to develop a problem-based learning (PBL) online student worksheet on green chemistry to enhance students' scientific literacy and numeracy. The research employed a research and development (RD) approach using the ADDIE model and involved 24 randomly selected students from SMA Negeri 4 Lhokseumawe. Data were collected using expert validation sheets, student response questionnaires, and pre- and post-test instruments. The validation results indicated that the online worksheet was highly feasible (media: 96.88%, content: 96.39%, Aiken's V = 0.95). User responses were very positive (82.42%), and the questionnaire instruments demonstrated high validity (Aiken's V = 0.97). The N-Gain scores revealed moderate improvement in both scientific literacy (0.6061) and numeracy (0.6106), reflecting strengthened critical thinking, data interpretation, and problem-solving skills. This study contributes by providing a replicable model of an online worksheet that integrates environmental issues into chemistry learning, enriches digital learning resources, and supports the mastery of 21st-century competencies in science education. Therefore, the development of this PBL-based online student worksheet is considered feasible, practical, and effective in enhancing students' scientific literacy and numeracy skills.